Genotoxicology Of N Nitroso Compounds
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Genotoxicology Of N Nitroso Compounds
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Author : T. Rao
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Genotoxicology Of N Nitroso Compounds written by T. Rao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Toph's in Chemical Mutagenesis is a new series dedicated to studies in the areas of environmental chemical mutagenesis and genetic toxicology. In this series we will explore some of many topics that are emerging in these rapidly developing fields. The purpose of the present volume is to attempt to organize and compare the genotoxic properties of the N-nitroso compounds. This is a particularly interesting class of compounds because of the problems encountered with the Salmonella assay of Ames in generating both false positive and false negative results. The battery approach using a number of assay systems seems more appropriate to evaluate chemicals in this class. Topics to be discussed in other volumes in this series include single-cell mutation monitoring systems, the detection of genetic damage in mammalian germ cells, the mutagenicity of pesticides, problems in monitoring human populations in genetic toxicology, and a glossary of terms in genetic toxicology. All of these books are in various stages of development and should appear within the next few years. Frederick J. de Serres Series Editor vii Preface During the past ten years there has been an explosive development in the number of short-term tests to predict the biological risks, especially risks of cancer, in exposure to xenobiotic chemicals. The number of published articles in this area has reached many thousands a year and there are several new journals devoted almost entirely to the presentation of the results obtained in these tests.
Genotoxicology Of N Nitroso Compounds
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Author : T. Rao
language : en
Publisher:
Release Date : 2014-01-15
Genotoxicology Of N Nitroso Compounds written by T. Rao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
Nitrosamines And Related N Nitroso Compounds
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Author : Richard N. Loeppky
language : en
Publisher:
Release Date : 1994
Nitrosamines And Related N Nitroso Compounds written by Richard N. Loeppky and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Investigates the compound formation, bioactivation, and detoxification of the N-nitroso group of compounds, which increasingly appears to be implicated in human carcinogenesis. The topics include exposure, formation, and blocking; nitric oxide; nitrosamine; toxic, mutagenic, and carcinogenic effects; and reactive intermediates. The 45 papers largely report on research rather than review the literature. The symposium that occasioned them was in Washington, DC, in August 1992. Annotation copyright by Book News, Inc., Portland, OR
Chemistry And Biology Of N Nitroso Compounds
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Author : William Lijinsky
language : en
Publisher: Cambridge University Press
Release Date : 1992-04-23
Chemistry And Biology Of N Nitroso Compounds written by William Lijinsky and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-04-23 with Medical categories.
Originally published in 1992, this volume looks in depth at the carcinogenic properties of N-nitroso compounds. These compounds occur widely in smoked foods and in meat and fish cured with nitrates; they are also formed in some industrial processes and in addition are found in cosmetics, tobacco and tobacco smoke. By focusing on the chemical and biological properties, the volume attempts to explain how these compounds exert their carcinogenic potential and, furthermore, goes on to explain how apparently harmless precursors such as nitrates and amines are transformed to produce carcinogens.
Mycotoxins N Nitroso Compounds
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Author : Ronald C. Shank
language : en
Publisher: CRC Press
Release Date : 1981-10-16
Mycotoxins N Nitroso Compounds written by Ronald C. Shank and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-10-16 with Medical categories.
N Nitroso Compounds
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Author :
language : en
Publisher:
Release Date : 1990
N Nitroso Compounds written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Carcinogenesis categories.
Environmental Carcinogens
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Author :
language : en
Publisher:
Release Date : 1983
Environmental Carcinogens written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Carcinogens categories.
Environmental N Nitroso Compounds
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Author :
language : en
Publisher:
Release Date : 1976
Environmental N Nitroso Compounds written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Cancer categories.
Nitrosamines
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Author : M. J. Hill
language : en
Publisher: Wiley-Blackwell
Release Date : 1988-10-15
Nitrosamines written by M. J. Hill and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-10-15 with Technology & Engineering categories.
Interest in the role of N-nitroso compounds in human cancer has magnified due to the widespread use of these compounds in all branches of carcinogenesis research. Here, a knowledge of the chemistry of N-nitrosation is necessary in order to understand the association between N-nitrosamines and human disease. This book opens with a discussion of the problems associated with the analysis of volatile N-nitrosamines, of the various groups of non-volatile N-nitroso compounds and of the apparent total N-nitroso compounds. This is followed by chapters on the chemistry of N-nitroso compounds and of N-nitrosation, on the mechanisms of the endogenous formation of N-nitroso compounds and on the occurrence of N-nitroso-amines and their precursors in the human environment. The next chapter reviews the toxico- logy of N-nitroso compounds in animals or in vitro assay systems considering acute and chronic toxicity, carcinogenicity and teratogenicity of N-nitroso-peptides and N-nitroso bile acids. The penultimate chapter deals with the evidence implicating N- nitroso compounds in human cancer, particularly of the stomach and urinary bladder but also of other sites. The final chapter is concerned with prospects for the future, particularly of N- nitroso compounds and human cancer.
Energy Research Abstracts
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Author :
language : en
Publisher:
Release Date : 1984
Energy Research Abstracts written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Power resources categories.