Germline Maintenance And Regeneration In The Amphipod Crustacean Parhyale Hawaiensis
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Germline Maintenance And Regeneration In The Amphipod Crustacean Parhyale Hawaiensis
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Author : Angela N. Kaczmarczyk
language : en
Publisher:
Release Date : 2014
Germline Maintenance And Regeneration In The Amphipod Crustacean Parhyale Hawaiensis written by Angela N. Kaczmarczyk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Because the germline eventually gives rise to gametes, which have the potential to become the next generation, it is arguably one of the most important cell types and understanding how the germline is specified and maintained throughout an organism's lifetime is a fundamental question in biology. This dissertation investigates the underlying mechanisms of germline specification, maintenance, and regeneration in the amphipod crustacean Parhyale hawaiensis. First I identified additional germline markers, Ph-piwi1, Ph-piwi2, Ph-tudor, and Ph-gustavus in Parhyale. Then I characterized the Parhyale adult germline stem cell (GSC) niche by using a combination of molecular markers (for germline and stem cell niche components) and using cell proliferation assays. I generated an antibody to Parhyale Vasa, which was instrumental in confidently identifying germline cells. In the Parhyale adult ovaries, this GSC niche likely resides within the germline ridge. Understanding where the putative GSC niche is important for evolutionary comparisons and can give clues as to how germline regeneration occurs. Finally, I investigate the potential role of bone morphogenetic protein (BMP) signaling in Parhyale germline maintenance and regeneration. This study provides insight into germline specification, the GSC niche, and adult regeneration in the amphipod crustacean, Parhyale hawaiensis.
Germ Line And Mesoderm Specification In The Amphipod Crustacean Parhyale Hawaiensis And Their Evolution In Anthropods
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Author : Günes Özhan-Kizil
language : en
Publisher:
Release Date : 2009
Germ Line And Mesoderm Specification In The Amphipod Crustacean Parhyale Hawaiensis And Their Evolution In Anthropods written by Günes Özhan-Kizil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Germ Line And Mesoderm Specifikation In The Amphipod Crustacean Parhyale Hawaiensis And Their Evolution In Arthropode
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Author : Günes Özhan-Kizil
language : en
Publisher:
Release Date : 2009
Germ Line And Mesoderm Specifikation In The Amphipod Crustacean Parhyale Hawaiensis And Their Evolution In Arthropode written by Günes Özhan-Kizil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Germ Line And Mesoderm Specifikation In The Amphipod Crustacean Parhyale Hawaiensis And Their Evolution In Arthropods
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Author : Günes Özhan-Kizil
language : en
Publisher:
Release Date : 2009
Germ Line And Mesoderm Specifikation In The Amphipod Crustacean Parhyale Hawaiensis And Their Evolution In Arthropods written by Günes Özhan-Kizil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Early Germline And Germ Layer Specification And Cuticle Differentiation In The Amphipod Crustacean Parhyale Hawaiensis
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Author : Johanna Havemann
language : en
Publisher:
Release Date : 2010
Early Germline And Germ Layer Specification And Cuticle Differentiation In The Amphipod Crustacean Parhyale Hawaiensis written by Johanna Havemann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Early Cells Fate Specification In The Amphipod Crustacean Parhyale Hawaiensis
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Author : Melinda Sue Modrell
language : en
Publisher:
Release Date : 2007
Early Cells Fate Specification In The Amphipod Crustacean Parhyale Hawaiensis written by Melinda Sue Modrell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
How Does Germline Regenerate
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Author : Kate MacCord
language : en
Publisher: University of Chicago Press
Release Date : 2024-01-05
How Does Germline Regenerate written by Kate MacCord and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-05 with categories.
A concise primer that complicates a convenient truth in biology--the divide between germ and somatic cells--with far-reaching ethical and public policy ramifications. Scientists have long held that we two have kinds of cells--germ and soma. Make a change to germ cells--say using genome editing--and that change will appear in the cells of future generations. Somatic cells are "safe" after such tampering; modify your skin cells, and your future children's skin cells will never know. And, while germ cells can give rise to new generations (including all of the somatic cells in a body), somatic cells can never become germ cells. How did scientists discover this relationship and distinction between somatic and germ cells--the so-called Weismann Barrier--and does it actually exist? Can somatic cells become germ cells in the way germ cells become somatic cells? That is, can germ cells regenerate from somatic cells even though conventional wisdom denies this possibility? Covering research from the late nineteenth century to the 2020s, historian and philosopher of science Kate MacCord explores how scientists came to understand and accept the dubious concept of the Weismann Barrier and what profound implications this convenient assumption has for research and policy, from genome editing to stem cell research, and much more.
What Is Regeneration
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Author : Jane Maienschein
language : en
Publisher: University of Chicago Press
Release Date : 2022-04-06
What Is Regeneration written by Jane Maienschein and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-06 with Science categories.
The idea of regeneration -- Observations and experiments -- Mechanisms of regeneration -- Living systems and different scales.
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Author : 珍．梅恩沙茵、凱特．麥蔻
language : zh-TW
Publisher: 時報文化出版
Release Date : 2023-03-31
written by 珍．梅恩沙茵、凱特．麥蔻 and has been published by 時報文化出版 this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-31 with Science categories.
一本好讀的入門書 介紹再生的歷史、哲學與科學 以及再生在醫學到生態學的應用 這本書展現許多非凡傑出之處，也提出一種獨特的途徑，不僅讓廣大讀者受益，也是應對人類與全球生態發展當前挑戰所必需的。這是一項重要的貢獻。 ──沃爾利切克（Hanna Lucia Worliczek），奧地利維也納大學 一本真正發人深省的書，不只適合學生與科學家，也適合政治人物與一般大眾。 ──羅廷格（Eric Röttinger），法國蔚藍海岸大學癌症與老化研究所 有些器官、組織，甚至生物在某些條件下，可以重新長出一部分或整個生命系統，然而有些器官、組織或生物，在任何條件下都無法再生。用正確的方式把蚯蚓切成兩半，你可能會遇到兩條扭動的蠕蟲。切除水螅的頭部，牠可能會長出新的頭，但切掉人類的一隻手臂，這個人會永遠少一隻手。 為何有如此差異？有哪些因子和哪些規則主導再生過程？真的有一套再生邏輯，也就是一組規則，貫穿生物學的各個領域以及生命的各種尺度嗎？從每一種生命系統內的再生，我們能學到什麼，又如何把這些知識轉譯到其他系統並做比較？此外，我們可以應用再生醫學治癒帕金森氏症、脊髓損傷、多種神經退化疾病的病人嗎？ 這是一本探討生物再生的入門書籍，簡短易讀，環顧從細菌、神經、幹細胞，到生物個體與複雜系統的各種尺度，提出一系列啟發思考的深刻問題，不論是政策制訂者、生物學家、歷史學家、哲學家、學生、教師及一般讀者，若能了解再生並想像這種過程怎樣在生命各尺度運作，都能從中獲益。並幫助讀者建立新觀點，把再生視為生命系統的一種過程，了解與幹細胞有關的科學和倫理問題。這種新觀點也會讓讀者體認到，所有生命系統是如何交織相連且互相影響。
Handbook Of Marine Model Organisms In Experimental Biology
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Author : Agnes Boutet
language : en
Publisher: CRC Press
Release Date : 2021-12-13
Handbook Of Marine Model Organisms In Experimental Biology written by Agnes Boutet and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-13 with Science categories.
The importance of molecular approaches for comparative biology and the rapid development of new molecular tools is unprecedented. The extraordinary molecular progress belies the need for understanding the development and basic biology of whole organisms. Vigorous international efforts to train the next-generation of experimental biologists must combine both levels – next generation molecular approaches and traditional organismal biology. This book provides cutting-edge chapters regarding the growing list of marine model organisms. Access to and practical advice on these model organisms have become a conditio sine qua non for a modern education of advanced undergraduate students, graduate students and postdocs working on marine model systems. Model organisms are not only tools they are also bridges between fields – from behavior, development and physiology to functional genomics. Key Features Offers deep insights into cutting-edge model system science Provides in-depth overviews of all prominent marine model organisms Illustrates challenging experimental approaches to model system research Serves as a reference book also for next-generation functional genomics applications Fills an urgent need for students Related Titles Jarret, R. L. & K. McCluskey, eds. The Biological Resources of Model Organisms (ISBN 978-1-1382-9461-5) Kim, S.-K. Healthcare Using Marine Organisms (ISBN 978-1-1382-9538-4) Mudher, A. & T. Newman, eds. Drosophila: A Toolbox for the Study of Neurodegenerative Disease (ISBN 978-0-4154-1185-1) Green, S. L. The Laboratory Xenopus sp. (ISBN 978-1-4200-9109-0)
