Glutathione
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Glutathione In Health And Disease
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Author : Pinar Erkekoglu
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-10-31
Glutathione In Health And Disease written by Pinar Erkekoglu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-31 with Science categories.
Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia. This book is mainly focused on GSH in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book.
The Glutathione Revolution
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Author : Nayan Patel
language : en
Publisher: Hachette UK
Release Date : 2020-09-08
The Glutathione Revolution written by Nayan Patel and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-08 with Health & Fitness categories.
Ward off life-threatening disease and symptoms of aging with this guide to boosting your levels of glutathione (GSH), the "master antioxidant." The body has a remarkable ability to ward off disease and heal itself--and it does it with the help of the most important antioxidant you've never heard of: glutathione (GSH), the "master antioxidant." This indispensable molecule--which we make ourselves--holds the key to immunity, vitality, and lifelong health, helping to flush out toxins, fight DNA-damaging free radicals, and rebuild other essential antioxidants like Vitamins C and E. It's been linked to longevity in centenarians, and it protects against diseases like cancer, diabetes, and Alzheimer's. It plays a role in lesser ailments too: low glutathione levels could be the culprit behind your fatigue, aches, and pains. At the forefront of the latest GSH research, Dr. Nayan Patel shares all the information you need to boost your glutathione levels, revitalize your body, and transform your life with this naturally-occurring super antioxidant. In The Glutathione Revolution, he addresses the most important questions about GSH: What exactly is glutathione? What happens when your GSH levels are low? What diseases does GSH ward off? How can you naturally increase the amount of GSH your cells produce? What foods should you eat--and not eat? What are the safest and most effective GSH supplements? With a wealth of practical information and three easy, accessible action plans that you can tailor to your own life and health concerns, you too can harness the power of glutathione.
Glutathione System And Oxidative Stress In Health And Disease
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-08-26
Glutathione System And Oxidative Stress In Health And Disease written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Science categories.
The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.
Glutathione And Sulfur Amino Acids In Human Health And Disease
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Author : Roberta Masella
language : en
Publisher: John Wiley & Sons
Release Date : 2009-08-06
Glutathione And Sulfur Amino Acids In Human Health And Disease written by Roberta Masella and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-06 with Technology & Engineering categories.
The complex roles of glutathione and sulfur amino acids in human health Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids. The twenty-two chapters explore such topics as: Chemistry, absorption, transport, and metabolism of GSH and sulfur amino acids Antioxidant and detoxification properties of GSH and sulfur amino acids, highlighting the enzymatic systems involved in antioxidant defenses Biological activities of GSH and sulfur amino acids and their role in modulating cell processes Role of GSH and sulfur amino acid deficiency and alteration in the onset of diseases and in aging Protective effects exerted by GSH and sulfur amino acids when used as drugs, functional foods, and nutraceuticals in humans and animals Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities, as well as the nutritional and therapeutic significance of dietary sulfur amino acids as shown in human and animal models. With more than 2,000 scientific references, this book provides food scientists, nutritionists, biochemists, food technologists, chemists, molecular biologists, and public health professionals with a comprehensive and up-to-date examination of glutathione and sulfur amino acids in human health and disease.
Glutathione
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Author : Leopold Flohe
language : en
Publisher: CRC Press
Release Date : 2018-08-29
Glutathione written by Leopold Flohe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-29 with Medical categories.
This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses. Other chapters review glutathione transport systems and glutathione peroxidases and their differences in substrate specificities and localization. Further contributions center on the diversified roles of different glutathione-S-transferases and the roles of nitrosoglutathione and glutaredoxins - a subfamily of redoxins. The book closes with discussions of the analogous or homologous thiol metabolism in pathogens and the potential suitability of involved enzymes as drug targets. Key selling features: Summarizing the way glutathione is involved in stress responses Compiling the multiple ways glutathione affects inflammatory responses Disclosing how glutathione dampens programmed cell death such as ferroptosis Exploring the enigma of how enzymes accelerate glutathione-dependent processes Discussing how detoxification and redox regulation is mediated by glutathionylation Reviewing the ways glutaredoxins catalyze protein disulfide reduction Highlighting the medical impact of glutathione-related metabolic pathways Illustrating the role thiol metabolism of pathogens might play in drug discovery Chapter 11 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution (CC-BY) 4.0 license.
Glutathione Centennial
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Author : Naoyuki Taniguchi
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Glutathione Centennial written by Naoyuki Taniguchi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Glutathione Centennial: Molecular Perspectives and Clinical Implications is a collection of papers presented at the international symposium by the same titles, held in Osaka, Japan on December 1-4, 1988. This symposium concentrates on the developments is glutathione field, especially those related to molecular and clinical problems. This book is organized into five parts encompassing 30 chapters. Part I deals with the metabolic regulation, thermodynamic and kinetic properties, and enzyme regulation of glutathione. Part II examines the gene expression and molecular mechanism of glutathione-related enzymes, while Part III explores the association between carcinogenesis, xenobiotic compounds, and glutathione. Part IV highlights the clinical implications of glutathione, particularly its effect on vasospasm in subarachnoid hemorrhage and experimental hepatitis. Part V discusses the mechanism and regulation of biological transport of glutathione. This book will be of great value to glutathione enthusiasts and to many scientists in the brad fields of biology and medicine, and to their students.
Glutathione S Transferases
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Author : Gerard J. Mulder
language : en
Publisher: CRC Press
Release Date : 1996-05-23
Glutathione S Transferases written by Gerard J. Mulder and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-05-23 with Science categories.
Glutathione s-transferases (GSTs) constitute the most important enzymes protecting human and many other organisms from potentially toxic chemicals, including drugs and carcinogens. This book reviews scientific developments in research of this enzyme
Glutathione
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Author : S. Colowick
language : en
Publisher: Elsevier
Release Date : 2014-05-12
Glutathione written by S. Colowick and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.
Glutathione: A Symposium covers the proceedings of the symposium held in Ridgefield, Connecticut in November 1953. The book focuses on the chemistry, characteristics, reactions, and properties of glutathione (GSH). The selection first offers information on mercaptans and disulfides, reactivity of the sulfhydryl group in GSH and related peptides, and chemistry and properties of GSH. Discussions focus on isolation and occurrence of GSH, properties of GSH, general chemistry of acidity, oxidation, and disulfides, and application to the structure of GSH. The text then examines thiol-thiolester complex formation, methods of GSH assay, and paper chromatography of GSH and its hydrolysis products. The publication takes a look at histochemical experiments on sulfhydryls and disulfides, enzymatic oxidation and reduction of GSH, and biosynthesis of GSH. Topics include synthesis of GSH from the constituent amino acids, enzymatic oxidation of GSH, and methods for demonstrating protein-bound sulfhydryl and disulfide groups in tissues. The selection is a dependable reference for researchers interested in the chemistry, reactions, and properties of glutathione.
Toxicology Of Glutathione Transferases
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Author : Yogesh C. Awasthi
language : en
Publisher: CRC Press
Release Date : 2006-07-27
Toxicology Of Glutathione Transferases written by Yogesh C. Awasthi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-27 with Medical categories.
Since the discovery of Glutathione S-Transferase (GST) or Glutathione transferase, studies have probed important questions about its pharmacological and physiological significance. Toxicology of Glutathione Transferases is the only text that details the methods used in GST research. With chapters written by experts who have been involved in
Glutathione
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Author : Ashley Wilber
language : en
Publisher: Nova Science Publishers
Release Date : 2014-12
Glutathione written by Ashley Wilber and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12 with Glutathione categories.
Glutathione is a widely mentioned biochemical molecule in present clinical biochemistry. There is no doubt that glutathione has several advantages to human bodies. Hence, there are many applications of glutathione products in present biomedicine. Glutathione plays a critical role in cell signalling and antioxidant defences. It plays a significant role in subjects with periodontitis and associated systemic comorbidities. Its depletion leads to oxidative damage. This book discusses dietary sources of glutathione as well as the role it plays in cellular functions, and its therapeutic effects.