Glutathione Gsh
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Glutathione In Health And Disease
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Author : Pinar Erkekoglu
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-10-31
Glutathione In Health And Disease written by Pinar Erkekoglu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-31 with Science categories.
Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia. This book is mainly focused on GSH in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book.
The Glutathione Revolution
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Author : Nayan Patel
language : en
Publisher: Hachette UK
Release Date : 2020-09-08
The Glutathione Revolution written by Nayan Patel and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-08 with Health & Fitness categories.
Ward off life-threatening disease and symptoms of aging with this guide to boosting your levels of glutathione (GSH), the "master antioxidant." The body has a remarkable ability to ward off disease and heal itself--and it does it with the help of the most important antioxidant you've never heard of: glutathione (GSH), the "master antioxidant." This indispensable molecule--which we make ourselves--holds the key to immunity, vitality, and lifelong health, helping to flush out toxins, fight DNA-damaging free radicals, and rebuild other essential antioxidants like Vitamins C and E. It's been linked to longevity in centenarians, and it protects against diseases like cancer, diabetes, and Alzheimer's. It plays a role in lesser ailments too: low glutathione levels could be the culprit behind your fatigue, aches, and pains. At the forefront of the latest GSH research, Dr. Nayan Patel shares all the information you need to boost your glutathione levels, revitalize your body, and transform your life with this naturally-occurring super antioxidant. In The Glutathione Revolution, he addresses the most important questions about GSH: What exactly is glutathione? What happens when your GSH levels are low? What diseases does GSH ward off? How can you naturally increase the amount of GSH your cells produce? What foods should you eat--and not eat? What are the safest and most effective GSH supplements? With a wealth of practical information and three easy, accessible action plans that you can tailor to your own life and health concerns, you too can harness the power of glutathione.
Glutathione In Health And Disease
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Author : Belma Kocer-Gumusel
language : en
Publisher:
Release Date : 2018
Glutathione In Health And Disease written by Belma Kocer-Gumusel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Biology (General) categories.
Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia. This book is mainly focused on GSH in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book.
Glutathione System And Oxidative Stress In Health And Disease
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-08-26
Glutathione System And Oxidative Stress In Health And Disease written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Science categories.
The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.
Glutathione
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Author : S. Colowick
language : en
Publisher: Elsevier
Release Date : 2014-05-12
Glutathione written by S. Colowick and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.
Glutathione: A Symposium covers the proceedings of the symposium held in Ridgefield, Connecticut in November 1953. The book focuses on the chemistry, characteristics, reactions, and properties of glutathione (GSH). The selection first offers information on mercaptans and disulfides, reactivity of the sulfhydryl group in GSH and related peptides, and chemistry and properties of GSH. Discussions focus on isolation and occurrence of GSH, properties of GSH, general chemistry of acidity, oxidation, and disulfides, and application to the structure of GSH. The text then examines thiol-thiolester complex formation, methods of GSH assay, and paper chromatography of GSH and its hydrolysis products. The publication takes a look at histochemical experiments on sulfhydryls and disulfides, enzymatic oxidation and reduction of GSH, and biosynthesis of GSH. Topics include synthesis of GSH from the constituent amino acids, enzymatic oxidation of GSH, and methods for demonstrating protein-bound sulfhydryl and disulfide groups in tissues. The selection is a dependable reference for researchers interested in the chemistry, reactions, and properties of glutathione.
Glutathione And Sulfur Amino Acids In Human Health And Disease
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Author : Roberta Masella
language : en
Publisher: John Wiley & Sons
Release Date : 2009-08-06
Glutathione And Sulfur Amino Acids In Human Health And Disease written by Roberta Masella and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-06 with Technology & Engineering categories.
The complex roles of glutathione and sulfur amino acids in human health Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids. The twenty-two chapters explore such topics as: Chemistry, absorption, transport, and metabolism of GSH and sulfur amino acids Antioxidant and detoxification properties of GSH and sulfur amino acids, highlighting the enzymatic systems involved in antioxidant defenses Biological activities of GSH and sulfur amino acids and their role in modulating cell processes Role of GSH and sulfur amino acid deficiency and alteration in the onset of diseases and in aging Protective effects exerted by GSH and sulfur amino acids when used as drugs, functional foods, and nutraceuticals in humans and animals Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities, as well as the nutritional and therapeutic significance of dietary sulfur amino acids as shown in human and animal models. With more than 2,000 scientific references, this book provides food scientists, nutritionists, biochemists, food technologists, chemists, molecular biologists, and public health professionals with a comprehensive and up-to-date examination of glutathione and sulfur amino acids in human health and disease.
Glutathione
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Author : Pal Perjesi
language : en
Publisher:
Release Date : 2019-02-15
Glutathione written by Pal Perjesi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-15 with Glutathione categories.
Glutathione (GSH) is a ubiquitous tripeptide (γ-L-gluatamyl-Lcysteinyl-glycin) playing an important role in cellular redox homeostasis, defence against electrophilyc reactive species, and control of several cellular events, among others. Most of these cellular functions are related to its tiol (SH) function of the cysteine moiety. With increasing knowledge on the molecular basis of its cellular functions, use of GSH as a nutritional supplement is receiving increasing interest. The present book summarizes the recent literature and new develeopments on three distinct, but closely related topics: Production, biochemical functions, implications and applications of glutathione. The topics cover comprehensive reviews on physico-chemical characterization, pharmacopoeal qualification, biotechnological production, surveys on different analytical methods for its quantitation, and the role of several physiological abnormalities (e.g., cardiac disfunctions, neurological disorders, kidney injuries and different types of cancer) related to non-appropriate biosynthesis and/or metabolism of endogeneous GSH. The information presented represents a valuable source for advanced students, scholars, teachers and scientists (academic and industrial) interested or already engaged in research that involves glutathione.
Glutathione In Plant Growth Development And Stress Tolerance
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Author : Mohammad Anwar Hossain
language : en
Publisher: Springer
Release Date : 2017-11-21
Glutathione In Plant Growth Development And Stress Tolerance written by Mohammad Anwar Hossain and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-21 with Science categories.
Glutathione (γ-glutamyl-cysteinyl-glycine) is a ubiquitously distributed sulfurcontaining antioxidant molecule that plays key roles in the regulation of plant growth, development, and abiotic and biotic stress tolerance. It is one of the most powerful low-molecular-weight thiols, which rapidly accumulates in plant cells under stress. Recent in-depth studies on glutathione homeostasis (biosynthesis, degradation, compartmentalization, transport, and redox turnover) and the roles of glutathione in cell proliferation and environmental stress tolerance have provided new insights for plant biologists to conduct research aimed at deciphering the mechanisms associated with glutathione-mediated plant growth and stress responses, as well as to develop stress-tolerant crop plants. Glutathione has also been suggested to be a potential regulator of epigenetic modifications, playing important roles in the regulation of genes involved in the responses of plants to changing environments. The dynamic relationship between reduced glutathione (GSH) and reactive oxygen species (ROS) has been well documented, and glutathione has been shown to participate in several cell signaling and metabolic processes, involving the synthesis of protein, the transport of amino acids, DNA repair, the control of cell division, and programmed cell death. Two genes, gamma-glutamylcysteine synthetase (GSH1) and glutathione synthetase (GSH2), are involved in GSH synthesis, and genetic manipulation of these genes can modulate cellular glutathione levels. Any fluctuations in cellular GSH and oxidized glutathione (GSSG) levels have profound effects on plant growth and development, as glutathione is associated with the regulation of the cell cycle, redox signaling, enzymatic activities, defense gene expression, systemic acquired resistance, xenobiotic detoxification, and biological nitrogen fixation. Being a major constituent of the glyoxalase system and ascorbate-glutathione cycle, GSH helps to control multiple abiotic and biotic stress signaling pathways through the regulation of ROS and methylglyoxal (MG) levels. In addition, glutathione metabolism has the potential to be genetically or biochemically manipulated to develop stress-tolerant and nutritionally improved crop plants. Although significant progress has been made in investigating the multiple roles of glutathione in abiotic and biotic stress tolerance, many aspects of glutathione-mediated stress responses require additional research. The main objective of this volume is to explore the diverse roles of glutathione in plants by providing basic, comprehensive, and in-depth molecular information for advanced students, scholars, teachers, and scientists interested in or already engaged in research that involves glutathione. Finally, this book will be a valuable resource for future glutathione-related research and can be considered as a textbook for graduate students and as a reference book for frontline researchers working on glutathione metabolism in relation to plant growth, development, stress responses, and stress tolerance.
Glutathione S Transferases
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Author : Gerard J. Mulder
language : en
Publisher: CRC Press
Release Date : 1996-05-23
Glutathione S Transferases written by Gerard J. Mulder and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-05-23 with Science categories.
Glutathione s-transferases (GSTs) constitute the most important enzymes protecting human and many other organisms from potentially toxic chemicals, including drugs and carcinogens. This book reviews scientific developments in research of this enzyme
Glutathione In The Nervous System
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Author : Christopher Ari Shaw
language : en
Publisher: Routledge
Release Date : 2018-10-08
Glutathione In The Nervous System written by Christopher Ari Shaw and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-08 with Medical categories.
The goal of this text is to focus readers attention on three major areas; the origin and localization of GSH in the nervous system; the multiple effects of GSH on neural health activity; and the potential for alterations on GSH status to lead to neurological damage of the type observed in amyotrophic lateral sclerosis, Parkinson's disease and other neurological disorders. The text also touches upon the additional roles of the antoxidant GSH, including possible neurotransmitter action, redox modulation of ionotropic receptor function, and neuroprotection against exicitoxic actions of glutamate.