Green Techniques For Organic Synthesis And Medicinal Chemistry


Green Techniques For Organic Synthesis And Medicinal Chemistry
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Green Techniques For Organic Synthesis And Medicinal Chemistry


Green Techniques For Organic Synthesis And Medicinal Chemistry
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Author : Wei Zhang
language : en
Publisher: John Wiley & Sons
Release Date : 2018-03-19

Green Techniques For Organic Synthesis And Medicinal Chemistry written by Wei Zhang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-19 with Science categories.


An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.



Green Sustainable Process For Chemical And Environmental Engineering And Science


Green Sustainable Process For Chemical And Environmental Engineering And Science
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Author : Inamuddin
language : en
Publisher: Elsevier
Release Date : 2021-11-17

Green Sustainable Process For Chemical And Environmental Engineering And Science written by Inamuddin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-17 with Technology & Engineering categories.


Green Sustainable Process for Chemical and Environmental Engineering and Science: Switchable Solvents explores the preparation, properties, chemical processes and applications of this class of green solvents. The book provides an in-depth overview on the area of switchable solvents in various industrial applications, focusing on the purification and extraction of chemical compounds utilizing green chemistry protocols that include liquid-liquid, solid-liquid, liquid-gas and lipids separation technologies. In addition, it includes recent advances in greener extraction and separation processes. This book will be an invaluable guide to students, professors, scientists and R&D industrial specialists working in the field of sustainable chemistry, organic, analytical, chemical engineering, environmental and pharmaceutical sciences. Provides a broad overview of switchable solvents in sustainable chemical processes Compares the use of switchable solvents as greener solvents over conventional solvents Outlines eco-friendly organic synthesis and chemical processes using switchable solvents Lists various industrial separations/extraction processes using switchable solvents



Green Approaches In Medicinal Chemistry For Sustainable Drug Design


Green Approaches In Medicinal Chemistry For Sustainable Drug Design
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Author : Bimal Krishna Banik
language : en
Publisher: Elsevier
Release Date : 2024-05-31

Green Approaches In Medicinal Chemistry For Sustainable Drug Design written by Bimal Krishna Banik and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-31 with Science categories.


Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. Highlights the need for adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability



Organic Synthesis


Organic Synthesis
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Author : Belakatte Parameshwarappa Nandeshwarappa
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-05-27

Organic Synthesis written by Belakatte Parameshwarappa Nandeshwarappa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-27 with Science categories.


The book ‘Organic Synthesis - A Nascent Relook’ is a compendium of the recent progress in all aspects of organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic, green chemistry and medicinal chemistry, polymer chemistry, as well as analytical methods in organic chemistry. The book presents the latest developments in these fields. The chapters are written by chosen experts who are internationally known for their eminent research contributions. Organic synthesis is the complete chemical synthesis of a target molecule. In this book, special emphasis is given to the synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels.



Green Synthetic Approaches For Biologically Relevant Heterocycles


Green Synthetic Approaches For Biologically Relevant Heterocycles
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2021-03-20

Green Synthetic Approaches For Biologically Relevant Heterocycles written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-20 with Science categories.


Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability



Green Synthetic Approaches For Biologically Relevant Heterocycles


Green Synthetic Approaches For Biologically Relevant Heterocycles
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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2021-02-26

Green Synthetic Approaches For Biologically Relevant Heterocycles written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-26 with Science categories.


Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field with an emphasis on sustainability Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts Collates the experience of a global team of expert contributors



Contemporary Chemical Approaches For Green And Sustainable Drugs


Contemporary Chemical Approaches For Green And Sustainable Drugs
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Author : Marianna Torok
language : en
Publisher: Elsevier
Release Date : 2022-08-26

Contemporary Chemical Approaches For Green And Sustainable Drugs written by Marianna Torok and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-26 with Medical categories.


Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs Presents individual chapters written by renowned experts with diverse backgrounds Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project



Protecting Group Free Organic Synthesis


Protecting Group Free Organic Synthesis
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Author : Rodney A. Fernandes
language : en
Publisher: John Wiley & Sons
Release Date : 2018-05-25

Protecting Group Free Organic Synthesis written by Rodney A. Fernandes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-25 with Science categories.


Presents a comprehensive account of established protecting-group-free synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protecting-group-free synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protecting-group-free synthesis. Following this, the book presents information on protecting-group-free synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protecting-group-free synthesis using carbohydrates and of glycosyl derivatives, glycol-polymers and glyco-conjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protecting-group-free synthesis. A comprehensive account of established protecting-group-free (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical Protecting-Group-Free Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.



Green Chemistry Strategies For Drug Discovery


Green Chemistry Strategies For Drug Discovery
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Author : Emily A. Peterson
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015-06-30

Green Chemistry Strategies For Drug Discovery written by Emily A. Peterson and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-30 with Medical categories.


The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry. The necessary metrics are more difficult to obtain in drug discovery due to the diversity of reactions conducted. However, pharmaceutical companies are realizing that incorporation of green chemistry techniques at earlier stages of drug development can speed the development of a drug candidate. Edited by experts who have pioneered green chemistry efforts within their own institutions, this book provides a practical guide for both academic and industrial labs wanting to know where to start with introducing greener approaches for greatest return on investment. The Editors have taken a comprehensive approach to the topic covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case studies where green chemistry strategies have been implemented. Currently employed as well as emerging techniques for performing greener drug discovery chemistry are addressed as well as cutting-edge topics like biologics discovery. Moreover, important surrounding issues such as intellectual property are included. This book will serve as a practical guide for both academic and industrial chemists who work across the breadth of the drug discovery discipline. Ultimately, readers will learn how to incorporate green chemistry strategies into their everyday workflow without slowing down their science.



Applications Of Nanotechnology For Green Synthesis


Applications Of Nanotechnology For Green Synthesis
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Author : Inamuddin
language : en
Publisher: Springer Nature
Release Date : 2020-07-02

Applications Of Nanotechnology For Green Synthesis written by Inamuddin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-02 with Science categories.


Traditional methods in synthetic chemistry produce chemical waste and byproducts, yield smaller desired products, and generate toxic chemical substances, but the past two centuries have seen consistent, greener improvements in organic synthesis and transformations. These improvements have contributed to substance handling efficiency by using green-engineered forerunners like sustainable techniques, green processes, eco-friendly catalysis, and have minimized energy consumption, reduced potential waste, improved desired product yields, and avoided toxic organic precursors or solvents in organic synthesis. Green synthesis has the potential to have a major ecological and monetary impact on modern pharmaceutical R&D and organic chemistry fields. This book presents a broad scope of green techniques for medicinal, analytical, environmental, and organic chemistry applications. It presents an accessible overview of new innovations in the field, dissecting the highlights and green chemistry attributes of approaches to green synthesis, and provides cases to exhibit applications to pharmaceutical and organic chemistry. Although daily chemical processes are a major part of the sustainable development of pharmaceuticals and industrial products, the resulting environmental pollution of these processes is of worldwide concern. This edition discusses green chemistry techniques and sustainable processes involved in synthetic organic chemistry, natural products, drug syntheses, as well various useful industrial applications.