Guanylate Cyclase
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Guanylate Cyclase
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Author : Rameshwar K. Sharma
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Guanylate Cyclase written by Rameshwar K. Sharma and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
From somewhat enigmatic beginnings 40 years ago, guanylate cyclase research has emerged to occupy a position of prominence in the study of signal transduction. Guanylate cyclase has several intriguing features, including existence in two major forms, membrane and soluble, each independently regulated by distinct mechanisms. The membrane form gives rise to a fascinating signal transduction story important to both peptide hormones and sensory neurons. This volume covers the evolution of the field, peptide hormone receptor work, membrane guanylate cycles, related retinal diseases, and the biochemistry and physiology of the soluble form. The 16 chapters are written by leaders in the field.
Guanylate Cyclase And Cyclic Gmp
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Author : Thomas Krieg
language : en
Publisher: Humana
Release Date : 2016-08-23
Guanylate Cyclase And Cyclic Gmp written by Thomas Krieg and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Science categories.
Recently, many ground-breaking steps have been made towards better understanding NO/cGMP/PKG pathways, its components, substrates, and their localization within a given cell. These advances were only possible due to the development of sophisticated new techniques in the field. In Guanylate Cyclase and Cyclic GMP: Methods and Protocols expert researchers in the field seek to provide an overview of novel techniques to identify various elements of the NO/cGMP/PKG pathway and further characterize their function, signaling, localization, and importance on a cellular level and in whole animal models providing a higher patho-/physiological integration and relevance. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Guanylate Cyclase and Cyclic GMP: Methods and Protocols seeks to provide scientist current methods and a useful guide towards the possibility to apply these techniques to their own research.
Ca2 And Ca2 Interlocked Membrane Guanylate Cyclase Modulation Of Neuronal And Cardiovascular Signal Transduction
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Author : Rameshwar K Sharma
language : en
Publisher: Frontiers Media SA
Release Date : 2015-05-01
Ca2 And Ca2 Interlocked Membrane Guanylate Cyclase Modulation Of Neuronal And Cardiovascular Signal Transduction written by Rameshwar K Sharma and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-01 with Guanylate cyclase categories.
The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.
Multi Limbed Membrane Guanylate Cyclase Cellular Signaling Pathways
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Author : Rameshwar K. Sharma
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-03
Multi Limbed Membrane Guanylate Cyclase Cellular Signaling Pathways written by Rameshwar K. Sharma and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-03 with Science categories.
Tonic And Acute Nitric Oxide Signaling Through Soluble Guanylate Cyclase
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Author : Stephen Patrick Lewis Cary
language : en
Publisher:
Release Date : 2005
Tonic And Acute Nitric Oxide Signaling Through Soluble Guanylate Cyclase written by Stephen Patrick Lewis Cary and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Activation And Deactivation Of Soluble Guanylate Cyclase
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Author : Jonathan Alvin Winger
language : en
Publisher:
Release Date : 2004
Activation And Deactivation Of Soluble Guanylate Cyclase written by Jonathan Alvin Winger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
Identification And Characterization Of A Conserved Soluble Guanylate Cyclase Like Heme Domain That Discriminates Between Nitric Oxide And Oxygen
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Author : David Stanley Karow
language : en
Publisher:
Release Date : 2004
Identification And Characterization Of A Conserved Soluble Guanylate Cyclase Like Heme Domain That Discriminates Between Nitric Oxide And Oxygen written by David Stanley Karow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
Activation Of Soluble Guanylate Cyclase By Nitric Oxide
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Author : James Robert Stone
language : en
Publisher:
Release Date : 1997
Activation Of Soluble Guanylate Cyclase By Nitric Oxide written by James Robert Stone and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.
Cyclic Gmp Synthesis Metabolism And Function
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Author :
language : en
Publisher: Academic Press
Release Date : 1994-05-18
Cyclic Gmp Synthesis Metabolism And Function written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-18 with Medical categories.
This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed. Isoforms of guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis Cyclic GMP-dependent protein kinase Hormones and ligands that regulate GMP formation and/or metabolism Effects of cyclic GMP on other second messengers and some functions such as smooth muscle relaxation and ion transport Clinical studies with cyclic GMP and atrial natriuretic peptide Important questions and experiments for the future
Cgmp Generators Effectors And Therapeutic Implications
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Author : Harald H. H. W. Schmidt
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-17
Cgmp Generators Effectors And Therapeutic Implications written by Harald H. H. W. Schmidt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-17 with Science categories.
After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.