Guidance Framework For Testing Genetically Modified Mosquitoes
DOWNLOAD
Download Guidance Framework For Testing Genetically Modified Mosquitoes PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Guidance Framework For Testing Genetically Modified Mosquitoes book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Guidance Framework For Testing Genetically Modified Mosquitoes
DOWNLOAD
Author :
language : en
Publisher: World Health Organization
Release Date : 2021-05-18
Guidance Framework For Testing Genetically Modified Mosquitoes written by and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-18 with Medical categories.
Genetically Modified And Other Innovative Vector Control Technologies
DOWNLOAD
Author : Brij Kishore Tyagi
language : en
Publisher: Springer Nature
Release Date : 2022-01-01
Genetically Modified And Other Innovative Vector Control Technologies written by Brij Kishore Tyagi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-01 with Medical categories.
This book comprehensively covers the latest development in developing and deploying the genetically modified vectors, particularly Anopheles and Aedes mosquitoes responsible for transmitting malaria parasites and dengue viruses, the most deadly and/or debilitating among all the vector-borne diseases. It is considered timely and commensurate to bring about a book dealing with the various ecological, biological and social as well as regulatory aspects for the deployment of genetically modified vectors in special context with the biosafety of humans, his associates, and the environment. Written by an array of specialists and experts in various subjects of genetically modified organisms, this book centrally addresses the (i) basic principles of the genetic manipulation of vectors and they are potential impact on human and the environment, (ii) ecological, biological, ethical, legal and social implications of the use of genetically modified vectors, (iii) identification of potential hazards; assessment and management of risks for human and environment; risk/benefit analysis, (iv) principles and practices for the assessment and management of biosecurity and biosafety in laboratories (and in the field), (v) guiding principles for creation and management of institutional or national biosafety review boards and ethics review committees, and (vi) development and application of a biosafety regulatory framework and its related legal principles at national levels for securing the development and use of vector control methods based on genetic modification strategies. This publication will be useful to researchers, scientists, and professionals engaged in academic and research institutions, government or non-government, as well as students in universities and medical colleges.
Transgenic Insects 2nd Edition
DOWNLOAD
Author : Mark Q. Benedict
language : en
Publisher: CABI
Release Date : 2022-10-31
Transgenic Insects 2nd Edition written by Mark Q. Benedict and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-31 with Science categories.
Technology for modifying the genotypes and phenotypes of insects and other arthropods has steadily progressed with the development of more precise and powerful methods, most prominently transgenic modification. For many insect pests, there is now almost unlimited ability to modify phenotypes to benefit human health and agriculture. Precise DNA modifications and gene drive have the power to make wild-type populations less harmful in ways that could never have been performed with previous transgenic approaches. This transition from primarily laboratory science to greater application for field use has also necessitated greater development of modeling, ethical considerations and regulatory oversight. The 2nd Edition of Transgenic Insects contains chapters contributed by experts in the field that cover technologies and applications that are now possible. This edition includes increased attention to associated challenges of risk assessment, regulation, and public engagement. This book will be very valuable to students and researchers in entomology, molecular biology, genetics, public health and agriculture, and will also appeal to practitioners who are implementing the technology, and to regulators, stakeholders and ethicists.
Gene Drives On The Horizon
DOWNLOAD
Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2016-08-28
Gene Drives On The Horizon written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-28 with Science categories.
Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Hl 68 Genetically Modified Insects
DOWNLOAD
Author : The Stationery Office
language : en
Publisher: The Stationery Office
Release Date : 2015
Hl 68 Genetically Modified Insects written by The Stationery Office and has been published by The Stationery Office this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Business & Economics categories.
The problems caused by infectious disease and agricultural pests are real. Genetically modified (GM) insects have the potential to address both these problems. The UK is a world leader in the development of this technology. The European Union's regulatory process, however, is likely to hold back progress. There is a moral duty to test the potential of the technology. We therefore support further research and call for action to test the efficiency of the EU process via a trial which should also be used to drive public engagement. A recent study estimated there to be 390 million dengue infections per year. In 2015 there have been approximately 214 million cases of malaria and 438,000 deaths. Sub-Saharan Africa is particularly affected; so far this year, the region has been home to 89% of malaria cases and 91% of malaria deaths. Malaria is both preventable and curable, and increased efforts have seen significant reductions in malaria incidence (the rate of new cases) and deaths. Nevertheless, about 3.2 billion people, nearly half of the world's population, live in countries, territories and areas where malaria is endemic. By 2050 the world's population will likely increase by more than a third to over 9 billion people. World food production will be required to increase by 70% to feed this larger, more urban and richer population. Insect pests affect all aspects of food production, storage, transport and waste. The application of GM insect technology, together with advances in the broad area of biotechnology, has the potential to provide additional tools for the control of insect-borne diseases and crop pests. The conceivable prize is enormous and the opportunity must not be squandered. Our concern is that unless there is change, and an injection of momentum and urgency, it will be.
Rethinking Clinical Trials And Redefining Responsibility For Research Participants
DOWNLOAD
Author : Ike Iyioke
language : en
Publisher: Ethics International Press
Release Date : 2023-11-25
Rethinking Clinical Trials And Redefining Responsibility For Research Participants written by Ike Iyioke and has been published by Ethics International Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-25 with Medical categories.
This is a new treatment of clinical research ethics in an African context, and an indispensable resource for researchers, students, policy makers and research institutions interested in African research ethics. In re-appraising the African philosophical notion of selfhood, it argues for the need to re-conceptualize responsibility in clinical trials, pushing researchers to go beyond autonomy-based considerations based on the individual only, and to develop clinical trials that appropriately embed research subjects within their community and their environment. The African standpoint stresses communalism and communitarianism. As such, responsibility for, and by, the individual can only make sense through the community in which the individual is rooted. The book emphasizes the African viewpoint by making explicit the importance of the self in the re-contextualized arena of the community. It forces research ethicists to go beyond autonomy-based considerations for the individual only, and to appropriately embed research subjects within their community and their environment.
Genetic Control Of Insect Pest Species Achievements Challenges And Perspectives
DOWNLOAD
Author : Irina Häcker
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-01
Genetic Control Of Insect Pest Species Achievements Challenges And Perspectives written by Irina Häcker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-01 with Science categories.
Embedding New Technologies Into Society
DOWNLOAD
Author : Diana M. Bowman
language : en
Publisher: CRC Press
Release Date : 2017-09-01
Embedding New Technologies Into Society written by Diana M. Bowman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-01 with Law categories.
The embedding of any new technologies in society is challenging. The evolving state of the scientific art, often-unquantifiable risks and ill-defined developmental trajectories have the potential to hinder innovation and/or the commercial success of a technology. The are, however, a number of tools that can now be utilized by stakeholders to bridge the chasm that exists between the science and innovation dimensions on the one hand, and the societal dimensions on the other. This edited volume will draw together leading researchers from the domains of law, philosophy, political science, public administration and the natural sciences in order to demonstrate how tools such as, for example, constructive technology assessment, regulatory governance and societal scenarios, may be employed by stakeholders to assist in successfully embedding new technologies into society. This volume will focus primarily on the embedding of two emergent and emerging technologies: nanotechnologies and synthetic biology. Government, industry and the epistemic community continue to struggle with how best to balance the promised benefits of an emerging technology with concerns about its potential impacts. There is a growing body of literature that has examined these challenges from various cultural, scientific and jurisdictional dimensions. There is, however, much work that still needs to be done; this includes articulating the successes and failures of attempts to the societal embedding of technologies and their associated products. This edited volume is significant and timely, as unlike other books currently on the market, it shall draw from real work experiences and experiments designed anticipate the societal embedding of emerging technologies. This empirical work shall be supported by robust theoretical underpinnings.
The Deadly Air
DOWNLOAD
Author : Christian Jennings
language : en
Publisher: Guardian Books
Release Date :
The Deadly Air written by Christian Jennings and has been published by Guardian Books this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.
Hundreds of thousands of people die every year from malaria. No one’s quite sure of the exact number. It’s just too difficult to keep track of the disease as it tears through more than 200 million cases each year, many of them in countries wracked by war and blighted by other problems. What is certain is that it is people living in these situations and, more specifically, children aged under five, who suffer disproportionately. It is for these areas that universities and NGOs, drugs companies, governments and philanthropists from around the world are united in an ongoing battle against the disease. Malaria has been with us for thousands of years. The Ancient Egyptians had it; Chinese dynasties before them. One of the first treatments for the disease was quinine, brought to Europe from Peru in the mid-fifteenth century. In some arenas during the second world war, more soldiers were hospitalised by malaria than by injuries sustained during fighting. Today, malaria remains one of the most resilient and most adaptive diseases out there, constantly mutating as it finds ways around the drugs deployed to combat it. One of the key parts of the problem is the method by which malaria transmits itself from person to person: mosquito bites. Breeding, feeding and transmitting at an incredible rate, mosquitoes are unavoidable in whatever environment they live. Now, cutting edge science is being called upon to help save lives lost to malaria. By genetically modifying the mosquitoes, scientists are aiming to turn the disease’s vector against itself, severing the link that enables malaria to spread. In The Deadly Air, Christian Jennings mixes together his own experiences of suffering from malaria with a history of mankind’s struggle with the disease and an account of the scientists engaged in the modification of the mosquito’s genome. Rich in detail and scientific intrigue, The Deadly Air is the story of malaria and of the millions of lives at stake in our fight against it.
Genetic Control Of Malaria And Dengue
DOWNLOAD
Author : Zach N. Adelman
language : en
Publisher: Academic Press
Release Date : 2015-10-15
Genetic Control Of Malaria And Dengue written by Zach N. Adelman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-15 with Medical categories.
Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. - Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission - Provides a summary of the concepts of both population suppression and population replacement - Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies