Guide To Cytochromes P450
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Guide To Cytochromes P450
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Author : David F. V. Lewis
language : en
Publisher: CRC Press
Release Date : 2001-04-12
Guide To Cytochromes P450 written by David F. V. Lewis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-04-12 with Medical categories.
Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. Due to the extensive nature of this subject, which is an area of intense scientific interest, the field is rapidly advancing and there is a need for new textbooks to keep abreast of the latest developments. The book fulfils that role in providing a fast-track approach for those coming into the P450 field, either at postgraduate level or in particular within the pharmaceutical industry. A Guide to Cytochrome P450 Structure and Function acts as an adjunct to the previous book Cytochromes P450: Structure, Function and Mechanism. It reviews the current status of the P450 field in terms of our present knowledge and understanding of the enzymes structure and function, including their multiplicity of forms, diversity of substrates, and selectivity. This is brought together with the latest research topics, including pharmacogenetics, regulation, human DMEs, toxicity screening and molecule modeling, to provide a fast-track approach for those new to the field.
Guide To Cytochromes
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Author : David F.V. Lewis
language : en
Publisher: CRC Press
Release Date : 1996-07-03
Guide To Cytochromes written by David F.V. Lewis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-03 with Science categories.
This guide to the structure, function and mechanism of the cytochromes P450 focuses on the role of P450s in xenobiotic metabolism and toxicity. Colour illustrations show how modelling of P450s can rationalize their substrate specificity for the metabolism of both endogenous and exogenous chemicals.
Guide To Cytochrome P450 Structure And Function
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Author : D. F. V. Lewis
language : en
Publisher:
Release Date : 2001
Guide To Cytochrome P450 Structure And Function written by D. F. V. Lewis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with MEDICAL categories.
Concise Guide To The Cytochrome P450 System
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Author : Kelly L. Cozza
language : en
Publisher: American Psychiatric Publishing
Release Date : 2001
Concise Guide To The Cytochrome P450 System written by Kelly L. Cozza and has been published by American Psychiatric Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
Adverse medication reactions account for up to 7,000 deaths annually in the United States. In today's era of polypharmacy, busy clinicians - especially those who practice in medical/surgical settings - must be able to quickly find and even anticipate psychiatric drug interactions.
Cytochrome P450
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Author :
language : en
Publisher:
Release Date : 2021
Cytochrome P450 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Cytochrome P-450 categories.
Cytochrome P450
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Author : Paul R. Ortiz de Montellano
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-05
Cytochrome P450 written by Paul R. Ortiz de Montellano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-05 with Medical categories.
Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.
Guide To Cytochromes
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Author : David F. V. Lewis
language : en
Publisher: CRC Press
Release Date : 2001-08-23
Guide To Cytochromes written by David F. V. Lewis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-23 with Medical categories.
Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. Due to the extensive nature of this subject, which is an area of intense scientific interest, the field is rapidly advancing and there is a need for new textbooks to keep abreast of the latest developments. The book fulfils that role in providing a fast-track approach for those coming into the P450 field, either at postgraduate level or in particular within the pharmaceutical industry. A Guide to Cytochrome P450 Structure and Function acts as an adjunct to the previous book Cytochromes P450: Structure, Function and Mechanism. It reviews the current status of the P450 field in terms of our present knowledge and understanding of the enzymes structure and function, including their multiplicity of forms, diversity of substrates, and selectivity. This is brought together with the latest research topics, including pharmacogenetics, regulation, human DMEs, toxicity screening and molecule modeling, to provide a fast-track approach for those new to the field.
Guide To Cytochromes P450
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Author : David F.V. Lewis
language : en
Publisher: CRC Press
Release Date : 1996-07-03
Guide To Cytochromes P450 written by David F.V. Lewis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-03 with Science categories.
This book covers the relevant aspects of cytochromes P450 for understanding their structure, function and mechanisms of action, such as physicochemical characterization methods, redox interactions, evolution and genetics, experimental and theoretical models, induction, inhibition and metabolism.
Lexi Comp S Drug Interactions Handbook
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Author : Kenneth A. Bachmann
language : en
Publisher:
Release Date : 2004
Lexi Comp S Drug Interactions Handbook written by Kenneth A. Bachmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cytochrome P-450 categories.
Concise Guide To Drug Interaction Principles For Medical Practice
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Author : Kelly L. Cozza
language : en
Publisher: American Psychiatric Publishing
Release Date : 2003
Concise Guide To Drug Interaction Principles For Medical Practice written by Kelly L. Cozza and has been published by American Psychiatric Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
An understanding of drug interactions has become essential to the practice of medicine. Since publication of the first edition of this Concise Guide in 2001, our increasing pharmacopoeia—coupled with prolonged human life spans—has made polypharmacy commonplace. Like the first edition of this unique pocket reference, the Second Edition is written expressly for clinicians. With four new contributors, this bestseller includes expanded sections on both phase I and phase II metabolism, updates of existing chapters and tables, new graphics, and extensive Web site references. Brand-new chapters discuss P-glycoproteins, "minor" cytochrome P450 enzymes, pain management with narcotic and nonnarcotic analgesics, prescribing guidelines, and medicolegal issues. This exceptionally practical guide is divided into four parts: 1. An easy-to-read, succinct review of pharmacology, written with clinicians in mind, explaining the importance of understanding our metabolic system and pharmacokinetics and P-glycoprotein drug interactions. 2. Thorough, carefully referenced reviews of the most clinically relevant phase I and phase II metabolic enzymes highlighted with newly expanded tables and study cases. 3. A section unique to this book on drug interactions by medical specialty, with drug tables arranged by how they are used in specialties such as gynecology, infectious diseases, internal medicine, neurology, oncology, psychiatry, and pain medicine. 4. Chapters on practical matters: prescribing guidelines, how to identify drug interaction patterns, strategies for reviewing the current literature, and medicolegal concerns. Enhanced by detailed descriptions and clinically based explanations, and complemented by a unique pocket guide to the most common and potent inhibitors and inducers of drug metabolism, this updated concise "how-to" guide will prove indispensable for busy students, teachers, and practitioners in all medically specialties.