Gut Microbiome Related Diseases And Therapies

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Gut Microbiome Related Diseases And Therapies

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Author : Maria Gazouli
language : en
Publisher: Springer Nature
Release Date : 2021-04-24

Gut Microbiome Related Diseases And Therapies written by Maria Gazouli and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-24 with Medical categories.

This book reviews recent knowledge of the role of gut microbiome in health and disease. It covers extensive topics for several diseases, including metabolic-related diseases, allergies, gastrointestinal diseases, psychiatric diseases, and cancer, while also discussing therapeutic approaches by microbiota modification. Comprehensive and cutting-edge, Gut Microbiome-Related Diseases and Therapies deepens a reader’s theoretical expertise in gut microbiome. Graduate and postdoctoral students, medical doctors, and biomedical researchers will benefit from this book.

The Interplay Of Microbiome And Immune Response In Health And Diseases

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Author : Gwendolyn Barcel´o-Coblijn
language : en
Publisher: MDPI
Release Date : 2019-11-06

The Interplay Of Microbiome And Immune Response In Health And Diseases written by Gwendolyn Barcel´o-Coblijn and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Medical categories.

[Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various—even distant—areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut–brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.]

Bugs As Drugs

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Author : Robert A. Britton
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-02

Bugs As Drugs written by Robert A. Britton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-02 with Medical categories.

Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

Human Microbiota In Health And Disease

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Author : Bryan Tungland
language : en
Publisher: Academic Press
Release Date : 2018-05-25

Human Microbiota In Health And Disease written by Bryan Tungland and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-25 with Science categories.

Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease

Microbiome Therapeutics

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Author : Nar Singh Chauhan
language : en
Publisher: Elsevier
Release Date : 2023-05-17

Microbiome Therapeutics written by Nar Singh Chauhan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-17 with Science categories.

Microbiome Therapeutics: Personalized Therapy Beyond Conventional Approaches addresses the current knowledge and landscape of microbiome therapeutics, providing an overview of existing applications in health and disease as well as potential future directions of microbiome modulations and subsequent translation to the global industry and market. This important reference provides the most current status of microbiome therapeutics as well as possible future perspectives through coverage of topics including the application of microbiome therapeutics; various additive, subtractive and modulatory approaches; microbiome composition of health and diseases, insights into live bio-therapeutics and the clinical data supporting their efficacy. Case studies are provided throughout the book to further define, describe and evaluate microbiome therapeutics success and failure. Provides chapters focused on illness types to address the potential of microbiome therapeutics in several significant disorders Offers human gut microbiome explorations that have enriched the understanding of microbiome colonization, maturation, and dysbiosis in health and disease subsets Addresses important concepts like economic potential in the global therapeutics market as well as ethical, technical, and regulatory aspects

The Gut Microbiome

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Author : Gyula Mozsik
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-11-02

The Gut Microbiome written by Gyula Mozsik and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-02 with Medical categories.

In the last decades, the importance of gut microbiome has been linked to medical research on different diseases. Developments of other medical disciplines (human clinical pharmacology, clinical nutrition and dietetics, everyday medical treatments of antibiotics, changes in nutritional inhabits in different countries) also called attention to study the changes in the gut microbiome. This book contains five excellent review chapters in the field of gut microbiome, written by researchers from the USA, Canada, China, and India. These chapters present a critical review about some clinically important changes in the gut microbiome in the development of some human diseases and therapeutic possibilities (liver disease, cardiovascular diseases, brain diseases, gastrointestinal diseases). The book brings to attention the essential role of gut microbiome in keeping our life healthy. This book is addressed to experts of microbiology, podiatrists, gastroenterologists, internists, nutritional experts, cardiologists, basic and clinical researchers, as well as experts in the field of food industry.

The Gut Microbiome In Health And Disease

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Author : Dirk Haller
language : en
Publisher: Springer
Release Date : 2018-07-27

The Gut Microbiome In Health And Disease written by Dirk Haller and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-27 with Medical categories.

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Probiotic Research In Therapeutics

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Author : Kanwaljit Chopra
language : en
Publisher: Springer Nature
Release Date : 2022-05-04

Probiotic Research In Therapeutics written by Kanwaljit Chopra and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-04 with Medical categories.

This volume focuses on the potential use of probiotics in treating metabolic disorders such as diabetes mellitus, metabolic acidosis, and gut dysbiosis. Chapters draw an association between gut microbiota and its diversity with metabolic diseases like diabetes, obesity, related liver and gut disorders; gut-brain axis; increased inflammation, and a compromised immune system resulting from these manifestations and scope of intervention with probiotics. Special attention is laid on describing the mechanisms of action of such beneficial effects of probiotic administration. The ability of probiotics to decrease metabolic endotoxemia by restoring the disrupted intestinal mucosal barrier is also included. The volume is a comprehensive compilation describing the scope and application of probiotic and prebiotic therapy in treating metabolic disorders. Readers will discover how probiotics are not just confined to the microbiology industry but are showing promising results in the medical and pharmaceutical sectors.

Microbiome Immunity Digestive Health And Nutrition

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Author : Debasis Bagchi
language : en
Publisher: Academic Press
Release Date : 2022-07-21

Microbiome Immunity Digestive Health And Nutrition written by Debasis Bagchi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-21 with Technology & Engineering categories.

Microbiome, Immunity, Digestive Health and Nutrition: Epidemiology, Pathophysiology, Prevention and Treatment addresses a wide range of topics related to the role of nutrition in achieving and maintaining a healthy gut microbiome. Written by leading experts in the field, the book outlines the various foods, minerals, vitamins, dietary fibers, prebiotics, probiotics, nutritional supplements, phytochemicals and drugs that improve gut health. It specifically addresses molecular and cellular mechanisms and pathways by which these nutritional components contribute to the physiology and functionality of a healthy gut microbiome and gut health. Intended for nutrition researchers and practitioners, food experts, gastroenterologists, nurses, general practitioners, public health officials and health professionals, this book is sure to be a welcomed resource. Outlines the nutritional guidelines and healthy lifestyle that is important to boost gut health Demonstrates the effects of diverse environmental stressors in the disruption of the gastrointestinal ecology Discusses the molecular and immunological mechanisms associated with healthy gut microbiome functions Addresses how to boost healthy gut microflora and microbiome Suggests areas for future research of microbiome-based nutrition and therapies

The Gut Microbiota In Health And Disease

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Author : Nimmy Srivastava
language : en
Publisher: John Wiley & Sons
Release Date : 2023-09-06

The Gut Microbiota In Health And Disease written by Nimmy Srivastava and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-06 with Medical categories.

The Gut Microbiota in Health and Disease An accessible overview of the varied microorganisms of the gut The human gut contains an extraordinary array of microorganisms existing in intricate symbiosis with the body. The gut microbiota plays a crucial role in maintaining overall gut health and warding off disease. With up to 15% of the global population suffering from Irritable Bowel Syndrome (IBS) caused by improper composition of gut microbiota, understanding these organisms and their vital contribution to human health has never been more important. The Gut Microbiota in Health and Disease provides a concise, accessible introduction to gut microbiota and their contribution to human health. It offers not only an overview of the relevant microorganisms and their roles in the body, but also extended discussion of diseases caused by gut dysbiosis. It presents a crucial window into this growing body of research into a critical area of overall human health. The Gut Microbiota in Health and Disease, readers will also find: Detailed analysis of dysbiotic health conditions including obesity, diabetes, and more Thorough treatment of molecular techniques for the analysis gut microbial composition Discussion of the lowering diversity of bacteria in the gut and the corresponding impact on global health The Gut Microbiota in Health and Disease is essential for researchers and clinicians working in immunology, gastroenterology, clinical microbiology, and related fields, as well as for clinical dieticians and postgraduate or medical students studying in these areas.