Hadron Therapy Physics And Simulations
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Hadron Therapy Physics And Simulations
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Author : Marcos d’Ávila Nunes
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-01
Hadron Therapy Physics And Simulations written by Marcos d’Ávila Nunes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-01 with Science categories.
This brief provides an in-depth overview of the physics of hadron therapy, ranging from the history to the latest contributions to the subject. It covers the mechanisms of protons and carbon ions at the molecular level (DNA breaks and proteins 53BP1 and RPA), the physics and mathematics of accelerators (Cyclotron and Synchrotron), microdosimetry measurements (with new results so far achieved), and Monte Carlo simulations in hadron therapy using FLUKA (CERN) and MCHIT (FIAS) software. The text also includes information about proton therapy centers and carbon ion centers (PTCOG), as well as a comparison and discussion of both techniques in treatment planning and radiation monitoring. This brief is suitable for newcomers to medical physics as well as seasoned specialists in radiation oncology.
Hadron Therapy Physics And Simulations
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Author : Marcos d'Ávila Nunes
language : en
Publisher: Springer
Release Date : 2013-10-02
Hadron Therapy Physics And Simulations written by Marcos d'Ávila Nunes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-02 with Science categories.
This brief provides an in-depth overview of the physics of hadron therapy, ranging from the history to the latest contributions to the subject. It covers the mechanisms of protons and carbon ions at the molecular level (DNA breaks and proteins 53BP1 and RPA), the physics and mathematics of accelerators (Cyclotron and Synchrotron), microdosimetry measurements (with new results so far achieved), and Monte Carlo simulations in hadron therapy using FLUKA (CERN) and MCHIT (FIAS) software. The text also includes information about proton therapy centers and carbon ion centers (PTCOG), as well as a comparison and discussion of both techniques in treatment planning and radiation monitoring. This brief is suitable for newcomers to medical physics as well as seasoned specialists in radiation oncology.
Proton Therapy Physics
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Author : Harald Paganetti
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Proton Therapy Physics written by Harald Paganetti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.
Proton Therapy Physics Second Edition
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Author : Harald Paganetti
language : en
Publisher: CRC Press
Release Date : 2018-11-19
Proton Therapy Physics Second Edition written by Harald Paganetti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-19 with Science categories.
Expanding on the highly successful first edition, this second edition of Proton Therapy Physics has been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed. This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics. Features: Updated with the latest technologies and methods in the field, covering all delivery methods of proton therapy, including beam scanning and passive scattering Discusses clinical aspects, such as treatment planning and quality assurance Offers insight on the past, present, and future of proton therapy from a physics perspective
Theory Of Heavy Ion Collision Physics In Hadron Therapy
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Theory Of Heavy Ion Collision Physics In Hadron Therapy written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
Advances in Quantum Chemistry presents surveys of current topics in this rapidly developing field that has emerged at the cross section of the historically established areas of mathematics, physics, chemistry, and biology. It features detailed reviews written by leading international researchers. This volume focuses on the theory of heavy ion physics in medicine. Presents surveys of current topics in this rapidly developing field Features detailed reviews written by leading international researchers Focuses on the theory of heavy ion physics in medicine
Monte Carlo Techniques In Radiation Therapy
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Author : Joao Seco
language : en
Publisher: Taylor & Francis
Release Date : 2016-04-19
Monte Carlo Techniques In Radiation Therapy written by Joao Seco and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.
Modern cancer treatment relies on Monte Carlo simulations to help radiotherapists and clinical physicists better understand and compute radiation dose from imaging devices as well as exploit four-dimensional imaging data. With Monte Carlo-based treatment planning tools now available from commercial vendors, a complete transition to Monte Carlo-base
Towards Offline Pet Monitoring At A Cyclotron Based Proton Therapy Facility
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Author : Matthias Würl
language : en
Publisher: Springer
Release Date : 2016-05-30
Towards Offline Pet Monitoring At A Cyclotron Based Proton Therapy Facility written by Matthias Würl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-30 with Science categories.
Matthias Würl presents two essential steps to implement offline PET monitoring of proton dose delivery at a clinical facility, namely the setting up of an accurate Monte Carlo model of the clinical beamline and the experimental validation of positron emitter production cross-sections. In the first part, the field size dependence of the dose output is described for scanned proton beams. Both the Monte Carlo and an analytical computational beam model were able to accurately predict target dose, while the latter tends to overestimate dose in normal tissue. In the second part, the author presents PET measurements of different phantom materials, which were activated by the proton beam. The results indicate that for an irradiation with a high number of protons for the sake of good statistics, dead time losses of the PET scanner may become important and lead to an underestimation of positron-emitter production yields.
Monte Carlo In Heavy Charged Particle Therapy
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Author : Pablo Cirrone
language : en
Publisher: CRC Press
Release Date : 2023-11-08
Monte Carlo In Heavy Charged Particle Therapy written by Pablo Cirrone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-08 with Science categories.
This book explores the current difficulties and unsolved problems in the field of particle therapy and, after analysing them, discusses how (and if) innovative Monte Carlo approaches can be used to solve them. Each book chapter is dedicated to a different sub-discipline, including multi-ion treatments, flash-radiotherapy, laser-accelerated beams, nanoparticles effects, binary reactions to enhance radiobiology, and space-related issues. This is the first book able to provide a comprehensive insight into this exciting field and the growing use of Monte Carlo in medical physics. It will be of interest to graduate students in medicine and medical physics, in addition to researchers and clinical staff. Key Features: Explores the exciting and interdisciplinary topic of Monte Carlo in particle therapy and medicine. Addresses common challenges in the field. Edited by an authority on the subject, with chapter contributions from specialists. Pablo Cirrone is a medical physicist and researcher at the Laboratori Nazionali del Sud of INFN, Italy, where he supports and coordinates various experimental groups. Dr. Cirrone is an expert in the use of proton and ion in radiation treatment and of absolute and relative dosimetry in electron, photon and ion beam. He is an expert in the development and test of detectors for medical applications, of the production and use of laser-driven beams for medical and multidisciplinary applications and recipient of the Michael Gotein Award. He is active on many scientific committees and organizes national and international conferences. Giada Petringa is a researcher at the Laboratori Nazionali del Sud of INFN, Italy. Dr. Petringa has a professional experience in the field of Monte Carlo simulations for medical applications, dosimetry, microdosimetry, and diagnostics with conventional and laser-driven proton beams. In 2019 she had a MSCA-IF-2019 (Marie Sklodowska-Curie Actions-Individual Fellowship) grant funded by the European Community in the framework of the H2020 program. She is a member of the Editorial Board of the international journal Physica Medica - European Journal of Medical. She organized more than fifteen international Geant4 Schools. She is an official member of the Geant4 code Collaboration at CERN since 2019. She is a code developer, and she collaborates to maintain two of the official examples of the code.
Monte Carlo Techniques In Radiation Therapy
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Author : Frank Verhaegen
language : en
Publisher: CRC Press
Release Date : 2021-10-13
Monte Carlo Techniques In Radiation Therapy written by Frank Verhaegen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-13 with Medical categories.
About ten years after the first edition comes this second edition of Monte Carlo Techniques in Radiation Therapy: Introduction, Source Modelling, and Patient Dose Calculations, thoroughly updated and extended with the latest topics, edited by Frank Verhaegen and Joao Seco. This book aims to provide a brief introduction to the history and basics of Monte Carlo simulation, but again has a strong focus on applications in radiotherapy. Since the first edition, Monte Carlo simulation has found many new applications, which are included in detail. The applications sections in this book cover the following: Modelling transport of photons, electrons, protons, and ions Modelling radiation sources for external beam radiotherapy Modelling radiation sources for brachytherapy Design of radiation sources Modelling dynamic beam delivery Patient dose calculations in external beam radiotherapy Patient dose calculations in brachytherapy Use of artificial intelligence in Monte Carlo simulations This book is intended for both students and professionals, both novice and experienced, in medical radiotherapy physics. It combines overviews of development, methods, and references to facilitate Monte Carlo studies.
Monte Carlo Techniques In Radiation Therapy
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Author : Joao Seco
language : en
Publisher: CRC Press
Release Date : 2021-11-14
Monte Carlo Techniques In Radiation Therapy written by Joao Seco and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-14 with Medical categories.
Targets both students or professionals, both novice and experienced, in medical radiotherapy physics. Combines overviews of development, methods and references to facilitate Monte Carlo studies. Focuses on applications in radiotherapy.