Handbook Of Animal Models And Its Uses In Cancer Research

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Handbook Of Animal Models And Its Uses In Cancer Research
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Author : Surajit Pathak
language : en
Publisher: Springer Nature
Release Date : 2023-01-31
Handbook Of Animal Models And Its Uses In Cancer Research written by Surajit Pathak and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-31 with Medical categories.
This reference book compiles together different animal models in cancer research. It provides knowledge and a better understanding of the advancement of the molecular and cellular mechanisms associated with the progression, formation, and clinical results of various types of cancer from the evidence collected from animal models utilized for cancer research. It discusses animal models for screening anti-cancer drugs and exploration of gene therapy. It presents different methods used to construct cancer animal models and the progress of each animal model in tumor research. The book also highlights the applications of genetic engineering, including CRISP/Cas9, in designing and developing animal models for cancer research. Further, it discusses strategies for modeling animals for investigating growth, metastasis, tumor-associated inflammation and microenvironment, cancer stem cells, tumor heterogeneity, and therapeutic resistance. This book is s a valuable resource for basic and translational cancer researchers, clinicians, and health care.
3d Bioprinting In Cancer Applications
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Author : Fahima Dilnawaz
language : en
Publisher: Academic Press
Release Date : 2025-06-16
3d Bioprinting In Cancer Applications written by Fahima Dilnawaz and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-16 with Science categories.
3D bioprinting in Cancer Applications is an all-encompassing guide covering both fundamentals concerning biofabrication principles and intricate protocols for precise construction of biomimetric 3D systems supporting advanced cell culture development that faithfully recapitulates human disease hallmarks, with a special focus on cancer. This title fills the void left by existing publications overlooking essential aspects associated with combining multimodal medical imaging alongside precision cancer treatment options. In 12 chapters 3D bioprinting in cancer applications leads the reader from an introduction to bioprinting technologies for cancer models, to models for immunotherapy and tumour-immune interaction, to biomimetrics 3D models to the applications of all these models in 3D bioprinted cancer models . 3D bioprinting in cancer applications uniquely combines distinct modalities under a unified framework suitable not only for seasoned veterans but also newly minted trainees encountering these sophisticated practices for the first time. - Gives comprehensive insights on the use of phytocompounds in the synthesis of eco-friendly nanoparticles for enhanced drug delivery in cancer applications - Provides concise updates on fresh discoveries in 3D printed biotechnologies - Includes high-resolution depictions to enhance accessibility while avoiding too many lengthy equations or calculations impeding quick absorption of fundamental ideas - Contributed by distinguished investigators across multiple countries and different specialties critical for mastering 3D bioprinted models
Cancer Stem Cells And Signaling Pathways
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Author : Surajit Pathak
language : en
Publisher: Elsevier
Release Date : 2023-11-01
Cancer Stem Cells And Signaling Pathways written by Surajit Pathak and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-01 with Science categories.
Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression. - Presents cancer stem characteristics and their signaling pathways - Highlights the use of animal models for cancer research, the use of genetically modified stem cells to deliver antitumor agents, and the significance of stem cell signaling in drug discovery - Covers basic and translational research appropriate for scientists and clinicians exploring alternative treatments for various cancers
Plant Derived Bioactive Compounds In Human Health And Disease
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Author : Surajit Pathak
language : en
Publisher: CRC Press
Release Date : 2024-12-10
Plant Derived Bioactive Compounds In Human Health And Disease written by Surajit Pathak and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-10 with Medical categories.
This book offers a comprehensive review of the multifaceted role of phytochemicals in promoting human health and combating diseases. The initial chapters introduce phytochemicals, navigate the natural health landscape, and provide a foundational understanding of these bioactive compounds. The book unfolds the role of phytochemicals as a formidable defense against oxidative stress and explores the unique health benefits and nutritional significance of phytochemicals found in fruit peels. The subsequent chapters further discuss the therapeutic potential of phytochemicals, detailing their role in combating multidrug-resistant bacterial infections and modulating critical pathways in inflammation and cancer. This book also highlights the novel treatment strategies for amyloidosis using natural products, as well as the fascinating interplay between natural compounds and biogenic nanoparticles in the context of polycystic ovarian syndrome (PCOS). Further exploration includes the impact of plant-derived compounds on cancer stem cells and the recent advancements in ethnopharmacology for age-related brain disorders. Each chapter provides a thorough and up-to-date analysis of research findings, clinical applications, and future directions within the field. By presenting a holistic view of the diverse functions and benefits of phytochemicals, this book aims to inspire further investigation and innovation in this dynamic area of research, ultimately contributing to enhanced human health and well-being.
Cancer Immunology And Genetics An Interdisciplinary Approach
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2025-08-25
Cancer Immunology And Genetics An Interdisciplinary Approach written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-25 with Medical categories.
The “Cancer Immunology and Genetics: An Interdisciplinary Approach” is the twenty third volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on cancer immunology and genetics. The volume starts with a chapter on thymic stromal lymphopoietin and cancers, followed by other chapters on immunogenic cancer cell death and epigenetics. Tumor microenvironments, innate lymphoid cells, and tumor-associated macrophages are explained in subsequent chapters. Other chapters focus on telomere maintenance in cancer cells, single nucleotide polymorphisms, Human leukocyte antigen, long non-coding RNA, and microRNA as oncogenic features as well as diagnostic and therapeutic approaches. Finally, genome editing, targeting epigenetic readers, and pharmacogenomics of cancer chemotherapy are discussed in the last chapters. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for those who wish to have an update on cancer immunology and genetics.
Microbial Omics In Environment And Health
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Author : Minu Kesheri
language : en
Publisher: Springer Nature
Release Date : 2024-06-26
Microbial Omics In Environment And Health written by Minu Kesheri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-26 with Science categories.
This book describes the basic concepts and recent advances in new discoveries and technologies related to microbial omics and their role in environmental research and human health. The term "omics" refers to a blend of high-throughput analysis and traditional methods including genomics, transcriptomics, proteomics, lipidomics and metabolomics for a variety of applications in the field of life sciences, biomedical sciences, environmental sciences, and related industries. The book aims to fill the existing gap in terms of a comprehensive approach that incorporates recent advances in this dynamic field and provides an answer to why this field requires an interdisciplinary research approach. The focus of this book is on the applications of genomics, epigenomics, metagenomics, integrative omics, machine learning and microbiome research in environmental health, disease, wastewater epidemiology, antibiotic resistance, drug discovery, cancer, production of secondary metabolites of microbial origin, oxidative stress alleviating mechanisms, etc. The overall construction of this book emphasizes three major perspectives, namely, elaborate knowledge from fundamentals to recent advances in technologies about omics in general and its application in microbiology, environment, and health in particular; illustrative figures capable of easy visualization of complex pathways; and serving as a platform for highly demanded bioinformatics strategies including relevant codes, programming scripts, machine learning and use of artificial intelligence strategies needed to streamline the research outcomes. With global contributions from authors from internationally renowned organizations who excel in relevant research, this book will benefit bibliophiles and prospective audiences from the research fraternity, academia, professionals, and experts in the field of life sciences, biomedical as well as industries related to the development of drug design and novel advances in biotechnological applications.
Innovation And Emerging Technologies In Radiation Oncology An Issue Of Hematology Oncology Clinics Of North America
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Author : Dukagjin Blakaj
language : en
Publisher: Elsevier Health Sciences
Release Date : 2025-04-28
Innovation And Emerging Technologies In Radiation Oncology An Issue Of Hematology Oncology Clinics Of North America written by Dukagjin Blakaj and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-28 with Medical categories.
In this issue of Hematology/Oncology Clinics, guest editors Drs. Dukagjin Blakaj and Mauricio Gamez bring their considerable expertise to the topic of Innovation and Emerging Technologies in Radiation Oncology. Top experts cover key topics such as FLASH radiation therapy; biomarker driven treatment algorithms in radiation oncology; spatial fractionated radiation therapy (SFRT): mini beam applications in radiation oncology; microbiome and effects on oncology treatments; and many more. - Contains 16 relevant, practice-oriented topics including effects of radiation therapy in the tumor microenvironment and immune system; impact of social media on oncology care; regenerative medicine and toxicity management in radiation oncology; artificial intelligence, machine learning, and big data in radiation oncology; and more - Provides in-depth clinical reviews on innovation and emerging technologies in radiation oncology, offering actionable insights for clinical practice - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
Gut Microbiome And Brain Ageing
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Author : Surajit Pathak
language : en
Publisher: Springer Nature
Release Date : 2024-04-18
Gut Microbiome And Brain Ageing written by Surajit Pathak and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-18 with Science categories.
This book, Gut microbiome and Brain Ageing, deals with the mechanisms and phenomenon that relates gut microbiome and aging of the brain. This book will bring forth the connection between good gut and brain aging and includes some cutting edge research topics dealing with gut physiology and its importance as future therapeutic option in neurological disorders. The gut microbiome's impact on neuronal function, mediated by neurotransmitters, vitamins, and neuroactive microbial metabolites, is an exciting area of investigation that this book thoroughly explores. It also covers the pivotal role of the gut microbiome in the etiology of various neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), depression, or multiple sclerosis (MS). It also explores the expanding understanding of the importance of the early-life gut microbiota and its implications for long-term health consequences. This book primarily addresses researchers, clinicians, and doctoral andgraduate students working in biomedicine, neurobiology, nutrition, microbiology, and translational medicine streams.
Neuroprotective Effects Of Phytochemicals In Brain Ageing
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Author : Surajit Pathak
language : en
Publisher: Springer Nature
Release Date : 2024-06-05
Neuroprotective Effects Of Phytochemicals In Brain Ageing written by Surajit Pathak and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-05 with Science categories.
This book discusses the mechanism and therapeutic strategies of phytochemicals against brain ageing. It discusses the underlying anti-oxidative and anti-inflammatory mechanisms of the phytochemicals and the implications of these compounds in the prevention and treatment of geriatric diseases. It discusses the potential role of the highly complex interactive network between the gut and the brain in neurodegenerative diseases such as Parkinson’s disease (PD), and Alzheimer’s disease. The chapters provide insight into the mechanisms involved in brain ageing and the mechanism of actions of the phytochemicals that might be crucial in developing effective new therapies against brain ageing. The chapter also presents the mechanisms of action of phytoconstituents, bioavailabilities, and their effects on neuroinflammation. The chapters also examine the phytochemicals protection of neurons via targeting oxidative stress, mitochondrial dysfunction, neurotrophic factor deficit, apoptosis, and abnormal protein accumulation. This book aims to provide comprehensive and cutting-edge information on the potential neuroprotective role of phytochemicals on the brain and neurological disorders to researchers, neuroscientists, clinical nutritionists, and physicians.
Handbook Of Laboratory Animal Science
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Author : Jann Hau
language : en
Publisher: CRC Press
Release Date : 2002-10-28
Handbook Of Laboratory Animal Science written by Jann Hau and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-28 with Medical categories.
The second edition of an international bestseller, this book provides veterinary specialists as well as veterinary and biomedical researchers with detailed information about laboratory animal genetics, diseases, health monitoring, nutrition, and environmental impact on animal experiments. Completely revised and updated, Volume I now contains expand