Handbook Of Machine Learning Applications For Genomics
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Handbook Of Machine Learning Applications For Genomics
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Author : Sanjiban Sekhar Roy
language : en
Publisher: Springer Nature
Release Date : 2022-06-23
Handbook Of Machine Learning Applications For Genomics written by Sanjiban Sekhar Roy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-23 with Technology & Engineering categories.
Currently, machine learning is playing a pivotal role in the progress of genomics. The applications of machine learning are helping all to understand the emerging trends and the future scope of genomics. This book provides comprehensive coverage of machine learning applications such as DNN, CNN, and RNN, for predicting the sequence of DNA and RNA binding proteins, expression of the gene, and splicing control. In addition, the book addresses the effect of multiomics data analysis of cancers using tensor decomposition, machine learning techniques for protein engineering, CNN applications on genomics, challenges of long noncoding RNAs in human disease diagnosis, and how machine learning can be used as a tool to shape the future of medicine. More importantly, it gives a comparative analysis and validates the outcomes of machine learning methods on genomic data to the functional laboratory tests or by formal clinical assessment. The topics of this book will cater interest to academicians, practitioners working in the field of functional genomics, and machine learning. Also, this book shall guide comprehensively the graduate, postgraduates, and Ph.D. scholars working in these fields.
Bioinformatics Second Edition
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Author : Pierre Baldi
language : en
Publisher: MIT Press
Release Date : 2001-07-20
Bioinformatics Second Edition written by Pierre Baldi and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-20 with Computers categories.
A guide to machine learning approaches and their application to the analysis of biological data. An unprecedented wealth of data is being generated by genome sequencing projects and other experimental efforts to determine the structure and function of biological molecules. The demands and opportunities for interpreting these data are expanding rapidly. Bioinformatics is the development and application of computer methods for management, analysis, interpretation, and prediction, as well as for the design of experiments. Machine learning approaches (e.g., neural networks, hidden Markov models, and belief networks) are ideally suited for areas where there is a lot of data but little theory, which is the situation in molecular biology. The goal in machine learning is to extract useful information from a body of data by building good probabilistic models—and to automate the process as much as possible. In this book Pierre Baldi and Søren Brunak present the key machine learning approaches and apply them to the computational problems encountered in the analysis of biological data. The book is aimed both at biologists and biochemists who need to understand new data-driven algorithms and at those with a primary background in physics, mathematics, statistics, or computer science who need to know more about applications in molecular biology. This new second edition contains expanded coverage of probabilistic graphical models and of the applications of neural networks, as well as a new chapter on microarrays and gene expression. The entire text has been extensively revised.
Artificial Intelligence Bioinformatics Development And Application Of Tools For Omics And Inter Omics Studies
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Author : Angelo Facchiano
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-18
Artificial Intelligence Bioinformatics Development And Application Of Tools For Omics And Inter Omics Studies written by Angelo Facchiano and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-18 with categories.
Machine Learning And Systems Biology In Genomics And Health
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Author : Shailza Singh
language : en
Publisher: Springer Nature
Release Date : 2022-02-04
Machine Learning And Systems Biology In Genomics And Health written by Shailza Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-04 with Science categories.
This book discusses the application of machine learning in genomics. Machine Learning offers ample opportunities for Big Data to be assimilated and comprehended effectively using different frameworks. Stratification, diagnosis, classification and survival predictions encompass the different health care regimes representing unique challenges for data pre-processing, model training, refinement of the systems with clinical implications. The book discusses different models for in-depth analysis of different conditions. Machine Learning techniques have revolutionized genomic analysis. Different chapters of the book describe the role of Artificial Intelligence in clinical and genomic diagnostics. It discusses how systems biology is exploited in identifying the genetic markers for drug discovery and disease identification. Myriad number of diseases whether be infectious, metabolic, cancer can be dealt in effectively which combines the different omics data for precision medicine. Major breakthroughs in the field would help reflect more new innovations which are at their pinnacle stage. This book is useful for researchers in the fields of genomics, genetics, computational biology and bioinformatics.
Deep Learning For The Life Sciences
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Author : Bharath Ramsundar
language : en
Publisher: "O'Reilly Media, Inc."
Release Date : 2019-04-10
Deep Learning For The Life Sciences written by Bharath Ramsundar and has been published by "O'Reilly Media, Inc." this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-10 with Science categories.
Deep learning has already achieved remarkable results in many fields. Now it’s making waves throughout the sciences broadly and the life sciences in particular. This practical book teaches developers and scientists how to use deep learning for genomics, chemistry, biophysics, microscopy, medical analysis, and other fields. Ideal for practicing developers and scientists ready to apply their skills to scientific applications such as biology, genetics, and drug discovery, this book introduces several deep network primitives. You’ll follow a case study on the problem of designing new therapeutics that ties together physics, chemistry, biology, and medicine—an example that represents one of science’s greatest challenges. Learn the basics of performing machine learning on molecular data Understand why deep learning is a powerful tool for genetics and genomics Apply deep learning to understand biophysical systems Get a brief introduction to machine learning with DeepChem Use deep learning to analyze microscopic images Analyze medical scans using deep learning techniques Learn about variational autoencoders and generative adversarial networks Interpret what your model is doing and how it’s working
Deep Learning For Genomics
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Author : Upendra Kumar Devisetty
language : en
Publisher: Packt Publishing Ltd
Release Date : 2022-11-11
Deep Learning For Genomics written by Upendra Kumar Devisetty and has been published by Packt Publishing Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-11 with Computers categories.
Learn concepts, methodologies, and applications of deep learning for building predictive models from complex genomics data sets to overcome challenges in the life sciences and biotechnology industries Key FeaturesApply deep learning algorithms to solve real-world problems in the field of genomicsExtract biological insights from deep learning models built from genomic datasetsTrain, tune, evaluate, deploy, and monitor deep learning models for enabling predictions in genomicsBook Description Deep learning has shown remarkable promise in the field of genomics; however, there is a lack of a skilled deep learning workforce in this discipline. This book will help researchers and data scientists to stand out from the rest of the crowd and solve real-world problems in genomics by developing the necessary skill set. Starting with an introduction to the essential concepts, this book highlights the power of deep learning in handling big data in genomics. First, you'll learn about conventional genomics analysis, then transition to state-of-the-art machine learning-based genomics applications, and finally dive into deep learning approaches for genomics. The book covers all of the important deep learning algorithms commonly used by the research community and goes into the details of what they are, how they work, and their practical applications in genomics. The book dedicates an entire section to operationalizing deep learning models, which will provide the necessary hands-on tutorials for researchers and any deep learning practitioners to build, tune, interpret, deploy, evaluate, and monitor deep learning models from genomics big data sets. By the end of this book, you'll have learned about the challenges, best practices, and pitfalls of deep learning for genomics. What you will learnDiscover the machine learning applications for genomicsExplore deep learning concepts and methodologies for genomics applicationsUnderstand supervised deep learning algorithms for genomics applicationsGet to grips with unsupervised deep learning with autoencodersImprove deep learning models using generative modelsOperationalize deep learning models from genomics datasetsVisualize and interpret deep learning modelsUnderstand deep learning challenges, pitfalls, and best practicesWho this book is for This deep learning book is for machine learning engineers, data scientists, and academicians practicing in the field of genomics. It assumes that readers have intermediate Python programming knowledge, basic knowledge of Python libraries such as NumPy and Pandas to manipulate and parse data, Matplotlib, and Seaborn for visualizing data, along with a base in genomics and genomic analysis concepts.
Machine Learning Methods For Multi Omics Data Integration
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Author : Abedalrhman Alkhateeb
language : en
Publisher: Springer Nature
Release Date : 2023-12-15
Machine Learning Methods For Multi Omics Data Integration written by Abedalrhman Alkhateeb and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-15 with Science categories.
The advancement of biomedical engineering has enabled the generation of multi-omics data by developing high-throughput technologies, such as next-generation sequencing, mass spectrometry, and microarrays. Large-scale data sets for multiple omics platforms, including genomics, transcriptomics, proteomics, and metabolomics, have become more accessible and cost-effective over time. Integrating multi-omics data has become increasingly important in many research fields, such as bioinformatics, genomics, and systems biology. This integration allows researchers to understand complex interactions between biological molecules and pathways. It enables us to comprehensively understand complex biological systems, leading to new insights into disease mechanisms, drug discovery, and personalized medicine. Still, integrating various heterogeneous data types into a single learning model also comes with challenges. In this regard, learning algorithms have been vital in analyzing and integrating these large-scale heterogeneous data sets into one learning model. This book overviews the latest multi-omics technologies, machine learning techniques for data integration, and multi-omics databases for validation. It covers different types of learning for supervised and unsupervised learning techniques, including standard classifiers, deep learning, tensor factorization, ensemble learning, and clustering, among others. The book categorizes different levels of integrations, ranging from early, middle, or late-stage among multi-view models. The underlying models target different objectives, such as knowledge discovery, pattern recognition, disease-related biomarkers, and validation tools for multi-omics data. Finally, the book emphasizes practical applications and case studies, making it an essential resource for researchers and practitioners looking to apply machine learning to their multi-omics data sets. The book covers data preprocessing, feature selection, and model evaluation, providing readers with a practical guide to implementing machine learning techniques on various multi-omics data sets.
Handbook Of Computational Intelligence In Biomedical Engineering And Healthcare
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Author : Janmenjoy Nayak
language : en
Publisher: Academic Press
Release Date : 2021-04-08
Handbook Of Computational Intelligence In Biomedical Engineering And Healthcare written by Janmenjoy Nayak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-08 with Science categories.
Handbook of Computational Intelligence in Biomedical Engineering and Healthcare helps readers analyze and conduct advanced research in specialty healthcare applications surrounding oncology, genomics and genetic data, ontologies construction, bio-memetic systems, biomedical electronics, protein structure prediction, and biomedical data analysis. The book provides the reader with a comprehensive guide to advanced computational intelligence, spanning deep learning, fuzzy logic, connectionist systems, evolutionary computation, cellular automata, self-organizing systems, soft computing, and hybrid intelligent systems in biomedical and healthcare applications. Sections focus on important biomedical engineering applications, including biosensors, enzyme immobilization techniques, immuno-assays, and nanomaterials for biosensors and other biomedical techniques. Other sections cover gene-based solutions and applications through computational intelligence techniques and the impact of nonlinear/unstructured data on experimental analysis. Presents a comprehensive handbook that covers an Introduction to Computational Intelligence in Biomedical Engineering and Healthcare, Computational Intelligence Techniques, and Advanced and Emerging Techniques in Computational Intelligence Helps readers analyze and do advanced research in specialty healthcare applications Includes links to websites, videos, articles and other online content to expand and support primary learning objectives
Advanced Ai Techniques And Applications In Bioinformatics
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Author : Loveleen Gaur
language : en
Publisher: CRC Press
Release Date : 2021-10-17
Advanced Ai Techniques And Applications In Bioinformatics written by Loveleen Gaur and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-17 with Technology & Engineering categories.
The advanced AI techniques are essential for resolving various problematic aspects emerging in the field of bioinformatics. This book covers the recent approaches in artificial intelligence and machine learning methods and their applications in Genome and Gene editing, cancer drug discovery classification, and the protein folding algorithms among others. Deep learning, which is widely used in image processing, is also applicable in bioinformatics as one of the most popular artificial intelligence approaches. The wide range of applications discussed in this book are an indispensable resource for computer scientists, engineers, biologists, mathematicians, physicians, and medical informaticists. Features: Focusses on the cross-disciplinary relation between computer science and biology and the role of machine learning methods in resolving complex problems in bioinformatics Provides a comprehensive and balanced blend of topics and applications using various advanced algorithms Presents cutting-edge research methodologies in the area of AI methods when applied to bioinformatics and innovative solutions Discusses the AI/ML techniques, their use, and their potential for use in common and future bioinformatics applications Includes recent achievements in AI and bioinformatics contributed by a global team of researchers
Deep Learning Applications In Image Analysis
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Author : Sanjiban Sekhar Roy
language : en
Publisher: Springer Nature
Release Date : 2023-07-08
Deep Learning Applications In Image Analysis written by Sanjiban Sekhar Roy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-08 with Technology & Engineering categories.
This book provides state-of-the-art coverage of deep learning applications in image analysis. The book demonstrates various deep learning algorithms that can offer practical solutions for various image-related problems; also how these algorithms are used by scientists and scholars in industry and academia. This includes autoencoder and deep convolutional generative adversarial network in improving classification performance of Bangla handwritten characters, dealing with deep learning-based approaches using feature selection methods for automatic diagnosis of covid-19 disease from x-ray images, imbalance image data sets of classification, image captioning using deep transfer learning, developing a vehicle over speed detection system, creating an intelligent system for video-based proximity analysis, building a melanoma cancer detection system using deep learning, plant diseases classification using AlexNet, dealing with hyperspectral images using deep learning, chest x-ray image classification of pneumonia disease using efficient net and inceptionv3. The book also addresses the difficulty of implementing deep learning in terms of computation time and the complexity of reasoning and modelling different types of data where information is currently encoded. Each chapter has the application of various new or existing deep learning models such as Deep Neural Network (DNN) and Deep Convolutional Neural Networks (DCNN). The detailed utilization of deep learning packages that are available in MATLAB, Python and R programming environments have also been discussed, therefore, the readers will get to know about the practical implementation of deep learning as well. The content of this book is presented in a simple and lucid style for professionals, nonprofessionals, scientists, and students interested in the research area of deep learning applications in image analysis.