Handbook Of Neurodegenerative Disorders

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Handbook Of Neurodegenerative Disorders

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Author : Musthafa M. Essa
language : en
Publisher: Springer Nature
Release Date : 2024-10-23

Handbook Of Neurodegenerative Disorders written by Musthafa M. Essa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-23 with Science categories.

This Handbook discusses the pathology, etiology, pathogenesis, and therapeutic interventions of different neurodegenerative diseases. The initial section of the Handbook reviews the recent advances in understanding neurodegenerative diseases and the commonalities and differences between the major pathologies. The subsequent section presents recent developments in understanding fundamental biological mechanisms that influence the onset and development of neurodegenerative diseases. It provides current biomedical studies that are aimed at identifying the underlying causes of neurodegeneration. The book also examines the recent observations from biological, cellular, and studies from the model organisms for gaining mechanistic insights into neurodegenerative disorders. It also presents the epidemiological and genetics studies relevant to clinical aspects of neurodegenerative diseases. The book's subsequent chapters offer new and more effective therapeutic strategies to combat these devastating diseases. Towards the end, the Handbook presents recent advances in molecular diagnostics for neurodegenerative disorders and a perspective on the future directions to provide a framework for further developments and refinements of molecular diagnostics to combat neurodegenerative diseases.

Handbook Of Computational Neurodegeneration

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Author : Panagiotis Vlamos
language : en
Publisher: Springer Nature
Release Date : 2023-07-25

Handbook Of Computational Neurodegeneration written by Panagiotis Vlamos and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-25 with Medical categories.

The Handbook of Computational Neurodegeneration provides a comprehensive overview of the field and thus bridges the gap between standard textbooks of research on neurodegeneration and dispersed publications for specialists that have a narrowed focus on computational methods to study this complicated process. The handbook reviews the central issues and methodological approaches related to the field for which the reader pursues a thorough overview. It also conveys more advanced knowledge, thus serving both as an introductory text and as a starting point for an in-depth study of a specific area, as well as a quick reference source for the expert by reflecting the state of the art and future prospects. The book includes topics that are usually missing in standard textbooks and that are only marginally represented in the specific literature. The broad scope of this handbook is reflected by five major parts that facilitate an integration of computational concepts, methods and applications in the study of neurodegeneration. Each part is intended to stand on its own, giving an overview of the topic and the most important problems and approaches, which are supported by examples, practical applications, and proposed methodologies. The basic concepts and knowledge, standard procedures and methods are presented, as well as recent advances and new perspectives.

Neuropathology Of Neurodegenerative Diseases

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Author : Gabor G. Kovacs
language : en
Publisher: Cambridge University Press
Release Date : 2017-12-13

Neuropathology Of Neurodegenerative Diseases written by Gabor G. Kovacs and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-13 with Medical categories.

This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.

Handbook Of Traumatic Brain Injury And Neurodegeneration

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Author : R.J. Castellani
language : en
Publisher: IOS Press
Release Date : 2020-04-24

Handbook Of Traumatic Brain Injury And Neurodegeneration written by R.J. Castellani and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-24 with Medical categories.

Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.

The Handbook Of Neuroprotection

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Author : Kewal K. Jain
language : en
Publisher: Humana
Release Date : 2020-08-14

The Handbook Of Neuroprotection written by Kewal K. Jain and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-14 with Medical categories.

This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment. Since the publication of the first edition, advances in biotechnology, particularly in cell and gene therapies, are reflected in this volume, as are numerous new and repurposed drugs in clinical trials. Overall, The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of disorders of the central nervous system. In-depth and authoritative, The Handbook of Neuroprotection, Second Edition features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.

Handbook Of Innovations In Central Nervous System Regenerative Medicine

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Author : António Salgado
language : en
Publisher: Elsevier
Release Date : 2020-06-10

Handbook Of Innovations In Central Nervous System Regenerative Medicine written by António Salgado and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-10 with Medical categories.

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Essential Guide To Neurodegenerative Disorders

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Author : Wael Mohamed
language : en
Publisher: Elsevier
Release Date : 2024-11-24

Essential Guide To Neurodegenerative Disorders written by Wael Mohamed and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-24 with Medical categories.

Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches. - Reviews big data and neurodegeneration disorders, including gene mapping - Examines the structural basis of protein assembly into amyloid filaments in neurodegenerative disease - Covers the progress and challenges of pharmacotherapy of neurodegenerative disorders

Handbook Of Neurology

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Author : Minoru Oishi
language : en
Publisher: World Scientific
Release Date : 1997

Handbook Of Neurology written by Minoru Oishi and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.

This volume deals with the principles of neurological diagnosis and treatment. The management of common and treatable neurological diseases is presented in a concise format, making the book a handy, practical manual. Each page of the book consists of a table or figure designed to be easily memorized; these tables should be useful especially to those preparing for examinations. This book will be a valuable reference to both students and residents.

Handbook Of Decision Support Systems For Neurological Disorders

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Author : D. Jude Hemanth
language : en
Publisher: Elsevier
Release Date : 2021-04-07

Handbook Of Decision Support Systems For Neurological Disorders written by D. Jude Hemanth and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-07 with Medical categories.

Handbook of Decision Support Systems for Neurological Disorders provides readers with complete coverage of advanced computer-aided diagnosis systems for neurological disorders. While computer-aided decision support systems for different medical imaging modalities are available, this is the first book to solely concentrate on decision support systems for neurological disorders. Due to the increase in the prevalence of diseases such as Alzheimer, Parkinson's and Dementia, this book will have significant importance in the medical field. Topics discussed include recent computational approaches, different types of neurological disorders, deep convolution neural networks, generative adversarial networks, auto encoders, recurrent neural networks, and modified/hybrid artificial neural networks. Includes applications of computer intelligence and decision support systems for the diagnosis and analysis of a variety of neurological disorders Presents in-depth, technical coverage of computer-aided systems for tumor image classification, Alzheimer's disease detection, dementia detection using deep belief neural networks, and morphological approaches for stroke detection Covers disease diagnosis for cerebral palsy using auto-encoder approaches, contrast enhancement for performance enhanced diagnosis systems, autism detection using fuzzy logic systems, and autism detection using generative adversarial networks Written by engineers to help engineers, computer scientists, researchers and clinicians understand the technology and applications of decision support systems for neurological disorders

The Wiley Handbook On The Aging Mind And Brain

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Author : Matthew Rizzo
language : en
Publisher: John Wiley & Sons
Release Date : 2018-05-29

The Wiley Handbook On The Aging Mind And Brain written by Matthew Rizzo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-29 with Psychology categories.

A thought-provoking treatise on understanding and treating the aging mind and brain This handbook recognizes the critical issues surrounding mind and brain health by tackling overarching and pragmatic needs so as to better understand these multifaceted issues. This includes summarizing and synthesizing critical evidence, approaches, and strategies from multidisciplinary research—all of which have advanced our understanding of the neural substrates of attention, perception, memory, language, decision-making, motor behavior, social cognition, emotion, and other mental functions. Written by a plethora of health experts from around the world, The Wiley Handbook on the Aging Mind and Brain offers in-depth contributions in 7 sections: Introduction; Methods of Assessment; Brain Functions and Behavior across the Lifespan; Cognition, Behavior and Disease; Optimizing Brain Function in Health and Disease; Forensics, Competence, Legal, Ethics and Policy Issues; and Conclusion and New Directions. Geared toward improving the recognition, diagnosis, and treatment of many brain-based disorders that occur in older adults and that cause disability and death Seeks to advance the care of patients who have perceptual, cognitive, language, memory, emotional, and many other behavioral symptoms associated with these disorders Addresses principles and practice relevant to challenges posed by the US National Academy of Sciences and National Institute of Aging (NIA) Presents materials at a scientific level that is appropriate for a wide variety of providers The Wiley Handbook on the Aging Mind and Brain is an important text for neurologists, psychiatrists, psychologists, physiatrists, geriatricians, nurses, pharmacists, social workers, and other primary caregivers who care for patients in routine and specialty practices as well as students, interns, residents, and fellows.