Handbook Of Polymer Applications In Medicine And Medical Devices
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Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Kayvon Modjarrad
language : en
Publisher: Elsevier
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Kayvon Modjarrad and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Medical categories.
While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they're creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices. - Gathers discussions of a large number of applications of polymers in medicine in one place - Provides an insight into both the legal and clinical implications of device design - Relevant to industry, academic and medical professionals - Presents the latest developments in the field, including medical devices on a nano-scale
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Laurence W. McKeen
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Laurence W. McKeen and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
Medical devices range from simple devices, to test equipment, to implants. Plastics are used more and more in these devices, for weight, cost, and performance purposes. Examples of medical devices include surgical instruments, catheters, coronary stents, pacemakers, magnetic resonance imaging (MRI) machines, X-ray machines, prosthetic limbs, artificial hips/knees, surgical gloves, and bandages.
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Sina Ebnesajjad
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Sina Ebnesajjad and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
This chapter focuses on adhesives used in direct physiological contact in dental and medical procedures. Activity in both areas has been quite extensive outside the United States for decades. In contrast, adhesive use in medical devices, patches, and plasters has been ongoing in the United States for a long time. In the case of medical devices, adhesion is concerned with the joining of materials such as plastics, elastomers, textiles, metals, and ceramics, which are examined in other chapters of the present volume and are covered in various references [1–6], The coverage of this chapter is devoted to applications where to adhesives are in direct contact with tissues and other live organs.
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : André Colas
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by André Colas and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
Silicone materials have been widely used in medicine for over 60 years. Available in a variety of material types, they have unique chemical and physical properties that manifest in excellent biocompatibility and biodurability for many applications. Silicone elastomers have remarkably low glass-transition temperatures and maintain their flexibility over a wide temperature range, enabling them to withstand conditions from cold storage to steam autoclaving. They have high permeability to gases and many drugs, advantageous respectively in wound care or in transdermal drug delivery. They have low surface tension and remarkable chemical stability, enabling biocompatibility and biodurability in many long-term implant applications.
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Zheng Zhang
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Zheng Zhang and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Len Czuba
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Len Czuba and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
This chapter will present a look at the medical device market with a particular focus on the materials of construction of devices and what we can expect in new products looking ahead. A deeper look at some other trends that have an effect on the direction of the medical device industry will be done. Finally, consideration will be given to a number of global factors that can have dramatic effects on our industry.
Handbook Of Polymers In Medicine
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Author : Masoud Mozafari
language : en
Publisher: Woodhead Publishing
Release Date : 2023-08-30
Handbook Of Polymers In Medicine written by Masoud Mozafari and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-30 with Technology & Engineering categories.
Handbook of Polymers in Medicine combines core concepts and advanced research on polymers, providing a better understanding of this class of materials in medicine. The book covers all aspects of medical polymers from characteristics and biocompatibility, to the diverse array of applications in medicine. Chapters cover an introduction to polymers in medicine and the challenges associated with biocompatibility in human tissue, polyurethane and supramolecular polymers and their specific applications in medicine, from tissue regeneration to orthopedic surgery and cancer therapeutics. This book offers an interdisciplinary approach that will appeal to researchers in a range of disciplines, including biomedical engineering, materials science, chemistry, pharmacology and translational medicine. The book will also make a useful reference for clinicians and those in medical fields who are interested in materials for medical applications, as well as R&D groups involved in medical device design. - Systematically covers individual polymer classes, from characteristics and biocompatibility to applications in biomedicine - Covers a broad range of applications in medicine, such as cardiac tissue engineering, targeted drug delivery, dentistry, and more - Provides an interdisciplinary review of polymers in medicine, allowing advanced students and experienced researchers in a range of biomedical and clinical fields to learn more about this fast-evolving area
Polymers For Pharmaceutical And Biomedical Applications
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Author : Vandana Patravale
language : en
Publisher: Elsevier
Release Date : 2024-01-16
Polymers For Pharmaceutical And Biomedical Applications written by Vandana Patravale and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-16 with Medical categories.
Polymers for Pharmaceutical and Biomedical Applications: Fundamentals, Selection, and Preparation supports the successful selection, design, and development of polymers with the required properties and performance for a range of advanced pharmaceutical and biomedical applications. The book begins by introducing polymers for pharmaceutical and biomedical applications, examining classification, basic properties, structures, and grades. This is followed by in-depth chapters focusing on synthesis and modification, characterization techniques, and dissolution and solubility of polymers for pharmaceutical applications. Key applications are then highlighted, with chapters explaining in detail the preparation of polymers for conventional dosage, modified drug delivery, conjugates, advanced drug and gene delivery, medical devices, pharmaceutical packaging, tissue engineering, artificial organs, and dentistry. Throughout the book, the aim is to provide accessible, step-by-step coverage, supported by diagrams and case studies. Finally, safety and regulatory aspects are discussed. This is a valuable resource for all those who are newly approaching the field of polymers and product development for pharmaceutical and biomedical applications. This includes researchers and advanced students across polymer science, pharmaceutical science, biomaterials, biomedicine, healthcare, and chemistry, and scientists and R&D professionals in an industrial setting. - Explains fundamental concepts relating to the synthesis, modification, and characterization of polymers - Guides the reader towards successful selection of polymer systems for specific target applications - Addresses key challenges in this field that are supported by case studies and regulatory information
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Vinny R. Sastri
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Vinny R. Sastri and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
Over the past 2000 years, many devices have been developed and used in the mitigation and diagnosis of diseases. The materials used in these devices have ranged from stone, wood, metal, ceramics, and most recently plastics. Medical devices have also evolved in sophistication and complexity over time. With the formalization of the scientific method in the seventeenth century such devices became more prevalent [1]. Many medical devices were manufactured by doctors or small companies and sold directly to the public with no government standards or oversight. With the explosion of medical technology in the early twentieth century, several intermediaries had evolved between the medical device industry and the public. In 1879, Dr E.R. Squibb, in an address to the Medical Society of the State of New York, proposed the enactment of a national statute to regulate food and drugs [2]. It was not until 27 years later that the Food and Drug Act of 1906 was introduced into the Congress and signed into law by President Theodore Roosevelt [3]. At that time, devices that were harmful to human safety and health proliferated the market but regulation of medical devices by the Bureau of Chemistry (the precursor to the Food and Drug Administration—FDA) was limited to challenging commercial products only after they had been released into the market. Devices in the marketplace that were defective, adulterated, or misbranded were seized and the device manufacturers were prosecuted in a court of law, but only after the products were sold in the market and caused harm to the end users. Thus, there was a strong need for regulating the devices before they entered the marketplace. An FDA report [4], issued in September 1970, detailed as many as 10,000 injuries and 731 deaths from ineffective medical devices. The report recommended the formation of a regulatory system and body that would enforce the production and sale of safe and effective devices to the public. All medical devices already on the market would be inventoried and classified into a three-tiered system based on their criticality of end use. It also detailed requirements for records and reports, registration and inspection of establishments, and uniform quality assurance programs called good manufacturing practices (GMP). After much lobbying by the FDA, Senate bill SR 510, “The Medical Device Amendments of 1973” was introduced by Senator Edward M. Kennedy and was passed by the Senate in 1975. House bill HR 11124, introduced by Representative Paul Rogers, was passed by the House in 1976. These bills eventually became the Medical Device Amendments of 1976, and were signed into law by President Nixon. The Medical Device Amendments of 1976 became the basis for the medical device regulation in the United States to control and regulate the production of finished devices and thus the device manufacturers themselves.
Handbook Of Polymer Applications In Medicine And Medical Devices
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Author : Kayvon Modjarrad
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-12-05
Handbook Of Polymer Applications In Medicine And Medical Devices written by Kayvon Modjarrad and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-05 with Technology & Engineering categories.
The history of plastics and medical devices traces a complex course of slowly evolving ideas punctuated by moments of intellectual revolution. When viewed from the vantage of retrospect, it becomes apparent that milestones in the progress of biomaterial science represent culminations of gradual shifts in theory and iterative experimentation. This has been as true for methodological developments in polymer chemistry as it has for technological breakthroughs in medical equipment design. The two disciplines, though now inextricable from one another, initially advanced along largely separate and occasionally redundant paths. Until the latter decades of the twentieth century, physicians and surgeons modified existing materials to create and refine devices according to their clinical needs while chemists and engineers synthesized materials de novo without specific attention to their potential medical applications. In the modern era, however, the lines between the chemical and biological sciences have blurred, paving way for an interdisciplinary approach toward the design and application of medical plastics.