Handbook Of Receptors And Channels
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Handbook Of Receptors And Channels
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Author : R. Alan North
language : en
Publisher: CRC Press
Release Date : 1994-10-25
Handbook Of Receptors And Channels written by R. Alan North and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-25 with Science categories.
This authoritative and comprehensive volume presents a perspective in the molecular and cellular diversity of membrane ion channels. Written in an accessible format, it depicts the structure and function of each of the known classes of ion channels. Each chapter provides amino acid sequences, including data base accession numbers; views of secondary, tertiary and quaternary channel structure; and evolutionary relationships among channels.
Handbook Of Receptors And Channels
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Author : Stephen J. Peroutka
language : en
Publisher: CRC Press
Release Date : 1993-10-20
Handbook Of Receptors And Channels written by Stephen J. Peroutka and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-10-20 with Medical categories.
The cloning, sequencing, and expression of a variety of membrane receptors and channels indicate the existence of at least four "superfamilies" of molecular structures that mediate signal transduction. Presently, more than 400 receptors have been cloned and sequenced. The Handbook of Receptors and Channels is the first handbook series to present the enormous amount of new molecular biological receptor data in a practical and useful format. Each volume in this remarkable series will focus on a specific molecular superfamily of receptors. Complete amino acid sequence information on all cloned receptors, as well as relevant pharmacological information, will be included. Furthermore, the format for each of the volumes will be consistent to allow for easy comparisons of different molecular subtypes for a given transmitter. G Protein-Coupled Receptors is the first volume in this new handbook series. Topics covered in future volumes include:
Ligand And Voltage Gated Ion Channels
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Author : R. Alan North
language : en
Publisher:
Release Date : 1995
Ligand And Voltage Gated Ion Channels written by R. Alan North and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Ion channels categories.
Handbook Of Ion Channels
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Author : Jie Zheng
language : en
Publisher: CRC Press
Release Date : 2015-02-25
Handbook Of Ion Channels written by Jie Zheng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Medical categories.
The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce
The Rbi Handbook Of Receptor Classification
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Author : John L. Neumeyer
language : en
Publisher:
Release Date : 1994
The Rbi Handbook Of Receptor Classification written by John L. Neumeyer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Textbook Of Ion Channels Volume I
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Author : Jie Zheng
language : en
Publisher: CRC Press
Release Date : 2023-06-09
Textbook Of Ion Channels Volume I written by Jie Zheng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-09 with Medical categories.
The Textbook of Ion Channels is a set of three volumes providing a wide-ranging reference source on ion channels for students, instructors and researchers. Ion channels are membrane proteins that control the electrical properties of neurons and cardiac cells; mediate the detection and response to sensory stimuli like light, sound, odor, and taste; and regulate the response to physical stimuli like temperature and pressure. In non-excitable tissues, ion channels are instrumental for the regulation of basic salt balance that is critical for homeostasis. Ion channels are located at the surface membrane of cells, giving them the unique ability to communicate with the environment, as well as the membrane of intracellular organelles, allowing them to regulate internal homeostasis. Ion channels are fundamentally important for human health and diseases, and are important targets for pharmaceuticals in mental illness, heart disease, anesthesia, pain and other clinical applications. The modern methods used in their study are powerful and diverse, ranging from single ion-channel measurement techniques to models of ion channel diseases in animals, and human clinical trials for ion channel drugs. Volume I, Part 1 covers fundamental topics such as the basic principles of ion permeation and selectivity, voltage-dependent, ligand-dependent, and mechano-dependent ion channel activation mechanisms, the mechanisms for ion channel desensitization and inactivation, and basic ion channel pharmacology and inhibition. Volume I, Part 2 offers a practical guide of cardinal methods for researching ion channels, including heterologous expression and voltage-clamp and patch-clamp electrophysiology; isolation of native currents using patch clamping; modeling ion channel gating, structures, and its dynamics; crystallography and cryo-electron microscopy; fluorescence and paramagnetic resonance spectroscopy methods; and genetics approaches in model organisms. All three volumes give the reader an introduction to fundamental concepts needed to understand the mechanism of ion channels; a guide to the technical aspects of ion channel research; a modern guide to the properties of major ion channel families; and includes coverage of key examples of regulatory, physiological and disease roles for ion channels.
The G Protein Coupled Receptors Handbook
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Author : Lakshmi A. Devi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-01
The G Protein Coupled Receptors Handbook written by Lakshmi A. Devi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-01 with Medical categories.
A comprehensive survey of the many recent advances in the field of G protein-coupled receptors (GPCR). The authors describe the current knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They also present new findings about how GPCR dimerization/oligomerization modifies the properties of individual receptors and show how recent developments are leading to significant advances in drug discovery, such as the detection of ligands for orphan GPCRs. Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.
Receptor And Ion Channel Detection In The Brain
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Author : Rafael Luján
language : en
Publisher: Humana Press
Release Date : 2018-03-31
Receptor And Ion Channel Detection In The Brain written by Rafael Luján and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-31 with Medical categories.
Receptor and Ion Channel Detection in the Brain provides state-of-the-art and up-to-date methodological information on molecular, neuroanatomical and functional techniques that are currently used to study neurotransmitter receptors and ion channels in the brain. The chapters have been contributed by world-wide recognized neuroscientists who explain in an easy and detailed way well established and tested protocols embracing molecular, cellular, subcellular, anatomical and electrophysiological aspects of the brain. This comprehensive and practical manual is presented in a simple, step-by-step manner for laboratory use, and also offers unambiguous detail and key implementation advice that proves essential for successful results and facilitate choosing the best method for the target proteins under study. This work serves as a useful guide for young researchers and students in training as well as for neurologists and established scientists who wish to extend their repertoire of techniques.
Handbook Of Cell Signaling
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Author : Ralph A. Bradshaw
language : en
Publisher:
Release Date : 2004
Handbook Of Cell Signaling written by Ralph A. Bradshaw and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.
The Handbook of Cell Signaling is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The subject matter has been divided into five main parts (each of which is headed by a recognized expert in the field): * Initiation: Extracellular and Membrane Events * Transmission: Effectors and Cytosolic Events * Nuclear Responses: Gene Expression and Translation * Events in Intracellular Compartments * Cell-Cell and Cell-Matrix Interactions Covered in extensive detail, these areas will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Tabular and well-illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field! * Contains approximately 470 articles * Provides well-organized sections on each essential area in signaling * Includes discussion on everything from ligand/receptor interactions to organ/organism responses * Extremely user-friendly.
Mammalian Transient Receptor Potential Trp Cation Channels
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Author : Bernd Nilius
language : en
Publisher: Springer
Release Date : 2014-06-24
Mammalian Transient Receptor Potential Trp Cation Channels written by Bernd Nilius and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-24 with Medical categories.
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.