Handbook Of Statistical Genetics 1 2007

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Handbook Of Statistical Genetics 1 2007
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Author : David J. Balding
language : en
Publisher:
Release Date : 2007
Handbook Of Statistical Genetics 1 2007 written by David J. Balding and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Handbook Of Statistical Genetics
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Author : David J. Balding
language : en
Publisher: John Wiley & Sons
Release Date : 2008-06-10
Handbook Of Statistical Genetics written by David J. Balding and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-10 with Science categories.
The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.
Statistical Genetics Of Quantitative Traits
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Author : Rongling Wu
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-17
Statistical Genetics Of Quantitative Traits written by Rongling Wu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-17 with Science categories.
Most traits in nature and of importance to agriculture are quantitatively inherited. These traits are di?cult to study due to the complex nature of their inheritance. However, recent developments of genomic technologies provide a revolutionary means for unraveling the secrets of genetic variation in quantitative traits. Genomic te- nologies allow the molecular characterization of polymorphic markers throughout the entire genome that are then used to identify and map the genes or quantitative trait loci (QTLs) underlying a quantitative trait based on linkage analysis. Statistical analysis is a crucial tool for analyzing genome data, which are now becoming increasingly available for a variety of species, and for giving precise exp- nations regarding genetic variation in quantitative traits occurring among species, populations, families, and individuals. In 1989, Lander and Botstein published a ha- mark methodological paper for interval mapping that enables geneticists to detect and estimate individual QTL that control the phenotype of a trait. Today, interval mappingisanimportantstatisticaltoolforstudyingthegeneticsofquantitativetraits at the molecular level, and has led to the discovery of thousands of QTLs responsible for a variety of traits in plants, animals, and humans. In a recent study published in Science, Li, Zhou, and Sang (2006, 311, 1936–1939) were able to characterize the molecular basis of the reduction of grain shattering – a fundamental selection process for rice domestication – at the detected QTL by interval mapping.
Statistical Genetics
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Author : Benjamin Neale
language : en
Publisher: Garland Science
Release Date : 2007-11-30
Statistical Genetics written by Benjamin Neale and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-30 with Science categories.
Statistical Genetics is an advanced textbook focusing on conducting genome-wide linkage and association analysis in order to identify the genes responsible for complex behaviors and diseases. Starting with an introductory section on statistics and quantitative genetics, it covers both established and new methodologies, providing the genetic and statistical theory on which they are based. Each chapter is written by leading researchers, who give the reader the benefit of their experience with worked examples, study design, and sources of error. The text can be used in conjunction with an associated website (www.genemapping.org) that provides supplementary material and links to downloadable software.
Genetics And Evolution Of Infectious Diseases
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Author : Michel Tibayrenc
language : en
Publisher: Elsevier
Release Date : 2017-01-12
Genetics And Evolution Of Infectious Diseases written by Michel Tibayrenc and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-12 with Medical categories.
Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. - Takes an integrated approach to infectious diseases - Includes contributions from leading authorities - Provides the latest developments in the field of infectious disease
Teaching Epidemiology
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Author : Jørn Olsen
language : en
Publisher: OUP Oxford
Release Date : 2015-03-26
Teaching Epidemiology written by Jørn Olsen and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-26 with Medical categories.
Teaching epidemiology requires skill and knowledge, combined with a clear teaching strategy and good pedagogic skills. The general advice is simple: if you are not an expert on a topic, try to enrich your background knowledge before you start teaching. The new edition of Teaching Epidemiology helps you to do this and, by providing world-expert teachers' advice on how best to structure teaching, providing a unique insight into what has worked in their hands. This book will help you to tailor your own epidemiology teaching programme. The fourth edition of this established text has been fully revised and updated, drawing on new research findings and recently developed methods including research technologies in genetic epidemiology and method development in relation to causal analysis. Analytical tools provide teachers in the field with the skills to guide students at both undergraduate and postgraduate levels. Each chapter in Teaching Epidemiology comprises key concepts in epidemiology, subject specific methodologies, and disease specific issues, to provide expert assistance in the teaching of a wide range of epidemiology courses.
Genetics Of Populations
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Author : Philip W. Hedrick
language : en
Publisher: Jones & Bartlett Publishers
Release Date : 2009-12-29
Genetics Of Populations written by Philip W. Hedrick and has been published by Jones & Bartlett Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-29 with Science categories.
The Fourth Edition of Genetics of Populations is the most current, comprehensive, and accessible introduction to the field for advanced undergraduate and graduate students, and researchers in genetics, evolution, conservation, and related fields. In the past several years, interest in the application of population genetics principles to new molecular data has increased greatly, and Dr. Hedrick's new edition exemplifies his commitment to keeping pace with this dynamic area of study. Reorganized to allow students to focus more sharply on key material, the Fourth Edition integrates coverage of theoretical issues with a clear presentation of experimental population genetics and empirical data. Drawing examples from both recent and classic studies, and using a variety of organisms to illustrate the vast developments of population genetics, this text provides students and researchers with the most comprehensive resource in the field.
Handbook Of Statistical Genomics
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Author : David J. Balding
language : en
Publisher: John Wiley & Sons
Release Date : 2019-07-09
Handbook Of Statistical Genomics written by David J. Balding and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-09 with Science categories.
A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.
Biological Data Mining
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Author : Jake Y. Chen
language : en
Publisher: CRC Press
Release Date : 2009-09-01
Biological Data Mining written by Jake Y. Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-01 with Computers categories.
Like a data-guzzling turbo engine, advanced data mining has been powering post-genome biological studies for two decades. Reflecting this growth, Biological Data Mining presents comprehensive data mining concepts, theories, and applications in current biological and medical research. Each chapter is written by a distinguished team of interdisciplin
Handbook Of Behavior Genetics
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Author : Yong-Kyu Kim
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-25
Handbook Of Behavior Genetics written by Yong-Kyu Kim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-25 with Medical categories.
Behavior Genetics is an interdisciplinary area combining behavioral sciences and genetics. The study of behavior genetics has become increasingly important as we see growth spurts in finding genes involved in complex behaviors following on advances in molecular genetic techniques. This domain has now become a vast common ground for scientists from very diverse fields including psychology, psychiatry, neurology, endocrinology, biochemistry, neuroimaging, and genetics. However, there are not many textbooks or references to which students in behavior genetics can access for their research and class. The purpose of this handbook is to offer research guides to the studies of genetic and environmental influences on a variety of complex behaviors in humans and animals. Unlike previous behavior genetics textbooks, this handbook will discuss current research and topics of interest to psychologists, psychiatrists, and geneticists. Utilizing methodologies and theories commonly used in behavior genetics, each chapter will begin with an overview of the selected topic; current research and issues will be intensively reviewed; and we will direct future research on the topic at the end of the end of the chapter. So the handbook will integrate many of the basic issues of the Behavior Genetics and will enhance our understanding in many fields. Therefore, this handbook will provide future research endeavors for the next 10 years. Throughout this handbook the editor will collaborate with contributors who are internationally well known in the field. The Behavior Genetics Association members and the Behavior Genetics Editorial Advisory Board will be invited to review the manuscripts of this handbook.