Handbook Of Statistical Systems Biology
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Handbook Of Statistical Systems Biology
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Author : Michael Stumpf
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-09
Handbook Of Statistical Systems Biology written by Michael Stumpf and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-09 with Science categories.
Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.
Handbook Of Statistical Bioinformatics
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Author : Henry Horng-Shing Lu
language : en
Publisher: Springer Nature
Release Date : 2022-12-08
Handbook Of Statistical Bioinformatics written by Henry Horng-Shing Lu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-08 with Science categories.
Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.
Handbook Of Systems Biology
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Author : Marian Walhout
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Handbook Of Systems Biology written by Marian Walhout and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. - 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards - Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines - Includes the latest research developments in human and animal models to assist with translational research - Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers
Handbook On Biological Networks
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Author : Stefano Boccaletti
language : en
Publisher: World Scientific
Release Date : 2010
Handbook On Biological Networks written by Stefano Boccaletti and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Science categories.
Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research ? the study of complex networks. In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology.
Problem Solving Handbook In Computational Biology And Bioinformatics
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Author : Lenwood S. Heath
language : en
Publisher: Springer
Release Date : 2014-08-15
Problem Solving Handbook In Computational Biology And Bioinformatics written by Lenwood S. Heath and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-15 with Computers categories.
Bioinformatics is growing by leaps and bounds; theories/algorithms/statistical techniques are constantly evolving. Nevertheless, a core body of algorithmic ideas have emerged and researchers are beginning to adopt a "problem solving" approach to bioinformatics, wherein they use solutions to well-abstracted problems as building blocks to solve larger scope problems. Problem Solving Handbook for Computational Biology and Bioinformatics is an edited volume contributed by world renowned leaders in this field. This comprehensive handbook with problem solving emphasis, covers all relevant areas of computational biology and bioinformatics. Web resources and related themes are highlighted at every opportunity in this central easy-to-read reference. Designed for advanced-level students, researchers and professors in computer science and bioengineering as a reference or secondary text, this handbook is also suitable for professionals working in this industry.
Frontiers In Computational And Systems Biology
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Author : Jianfeng Feng
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-14
Frontiers In Computational And Systems Biology written by Jianfeng Feng and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-14 with Science categories.
Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual’s susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain–machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.
Handbook Of Statistics For Teaching And Research In Plant And Crop Science
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Author : Usha Palaniswamy
language : en
Publisher: CRC Press
Release Date : 2005-12-08
Handbook Of Statistics For Teaching And Research In Plant And Crop Science written by Usha Palaniswamy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-08 with Mathematics categories.
More than a textbook—it’s also a valuable reference book for researchers and crop science professionals! The Handbook of Statistics for Teaching and Research in Plant and Crop Science presents the fundamental concepts of important statistical methods and experimental designs to the students and researchers who need to apply them to their own specific problems. This comprehensive handbook takes what can be the difficult and confusing topics of statistics and experimental design and explains them in easily understandable terms, making them accessible to nearly every reader. More than a student textbook, it is an essential reference for researchers and professionals in a multitude of fields. Designed as a two-semester statistical textbook, the first section of the Handbook of Statistics for Teaching and Research in Plant and Crop Science focuses on statistical concepts, providing a foundation of useful knowledge on which you can base your own research. The second section concentrates on experimental designs in plant and crop sciences. The material is presented in a way that helps readers with a minimum of mathematical background to understand important theories and concepts. Derivations of formulas are avoided, and mathematical symbols are used only when essential. To illustrate the computational procedures, data is drawn from actual experiments. At the end of each chapter, examples and exercises are given to provide clear insight into real-life problems. A comprehensive appendix of clearly presented statistical tables is included. Part One of Handbook of Statistics for Teaching and Research in Plant and Crop Science focuses on statistical methods, principles, and procedures, exploring: methods of display of statistical information, such as tables, diagrams, graphs, etc. symbols and their use in denoting variables descriptions of types of statistical data methods of computation from raw and graphed data the importance of studying variables and dispersion in research the use of normal probability integral tables and their application to practical problems descriptions of different types of experiments, such as determinate and nondeterminate the significance of expected value in research special techniques in descriptive statistics explanations of population, sample, and statistical inference the significance of null hypothesis in research methods of correlation studies assumptions and principles in regression analysis Part Two concentrates on experimental design, principles and procedures, exploring: basic principles of experimental design the fundamental concepts of linear models and analysis of variance method and layout of Completely Randomized Design (CRD) the advantages and disadvantages of Randomized Complete Block Design (RCBD) methods and procedures for comparison of several treatment means the important features of Latin Square Design factorial experiments split plot design completely confounded design analysis of covariance the Chi Square Test of Significance the transformation of experimental data quality control and so much more! The Handbook of Statistics for Teaching and Research in Plant and Crop Science serves not only as a textbook for instructors and students in experimental design and statistics but also as a reference book on plant and crop sciences for professionals and researchers. The comprehensive text is also useful for professionals in other statistic-heavy fields.
Handbook Of Statistical Analysis And Data Mining Applications
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Author : Ken Yale
language : en
Publisher: Elsevier
Release Date : 2017-11-09
Handbook Of Statistical Analysis And Data Mining Applications written by Ken Yale and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-09 with Mathematics categories.
Handbook of Statistical Analysis and Data Mining Applications, Second Edition, is a comprehensive professional reference book that guides business analysts, scientists, engineers and researchers, both academic and industrial, through all stages of data analysis, model building and implementation. The handbook helps users discern technical and business problems, understand the strengths and weaknesses of modern data mining algorithms and employ the right statistical methods for practical application. This book is an ideal reference for users who want to address massive and complex datasets with novel statistical approaches and be able to objectively evaluate analyses and solutions. It has clear, intuitive explanations of the principles and tools for solving problems using modern analytic techniques and discusses their application to real problems in ways accessible and beneficial to practitioners across several areas—from science and engineering, to medicine, academia and commerce. - Includes input by practitioners for practitioners - Includes tutorials in numerous fields of study that provide step-by-step instruction on how to use supplied tools to build models - Contains practical advice from successful real-world implementations - Brings together, in a single resource, all the information a beginner needs to understand the tools and issues in data mining to build successful data mining solutions - Features clear, intuitive explanations of novel analytical tools and techniques, and their practical applications
Bioinformatics And Computational Biology Solutions Using R And Bioconductor
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Author : Robert Gentleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-29
Bioinformatics And Computational Biology Solutions Using R And Bioconductor written by Robert Gentleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-29 with Computers categories.
Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Information Processing And Biological Systems
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Author : Samuli Niiranen
language : en
Publisher: Springer
Release Date : 2013-04-21
Information Processing And Biological Systems written by Samuli Niiranen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-21 with Computers categories.
Living beings require constant information processing for survival. In cells, information is being processed and propagated at various levels, from the gene regulatory network to chemical pathways, to the interaction with the environment. How this is achieved and how information is coded is still poorly understood. For example, what a cell interprets as information in the temporal level of an mRNA and what is interpreted as noise remains an open question. Recently, information theoretical methods and other tools, developed in the context of engineering and natural sciences, have been applied to study diverse biological processes. This book covers the latest findings on how information is processed in various biological processes, ranging from information processing and propagation in gene regulatory networks to information processing in natural language. An overview is presented of the state-of-the-art in information processing in biological systems and the opinion of current leaders in this research field on future research directions.