Head And Neck Cancer Hallmarks Of The Inflammation Ecosystem

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Head And Neck Cancer Hallmarks Of The Inflammation Ecosystem

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Author : Norhafiza Mat Lazim
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-03-31

Head And Neck Cancer Hallmarks Of The Inflammation Ecosystem written by Norhafiza Mat Lazim and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-31 with Medical categories.

This reference comprehensively covers the clinical aspects of head and neck neoplasms while also highlighting the relationship that exists between inflammation and these cancers. This relationship is critical as it dictates the risks, assessment, treatment, and prognosis of head and neck cancer patients. The book starts with an introduction to the inflammation ecosystem in head and neck malignancy, followed by detailed discussions on the types of head and neck malignancy and their histological classification. The book then provides information about specialized topics relevant to the specialty of head and neck oncology. Key Features: - Comprehensive coverage of head and neck cancers with topic-based chapters - Introductory text explaining the basics of inflammation - Detailed information on the relationship between inflammation and head and neck neoplasms - Information about the classification of head and neck cancers - Methods for diagnosis and treatment - Special topics such as complications caused by HPV infections, chemoradiation, immune-targeted therapy, and inflammatory biomarkers - References for further reading The combination of basic and advanced topics makes this book an informative reference for medical students and professionals at all levels. Residents specializing in otolaryngology, oncology, and surgery as well as researchers studying inflammation will also gain an understanding of the subject in relation to oncogenesis.

Head And Neck Cancer Hallmarks Of The Inflammation Ecosystem Volume 2

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Author : Norhafiza Mat Lazim
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-03-30

Head And Neck Cancer Hallmarks Of The Inflammation Ecosystem Volume 2 written by Norhafiza Mat Lazim and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-30 with Medical categories.

This reference comprehensively covers the clinical aspects of head and neck neoplasms while also highlighting the relationship that exists between inflammation and these cancers. This relationship is critical as it dictates the risks, assessment, treatment, and prognosis of head and neck cancer patients. The book starts with an introduction to the inflammation ecosystem in head and neck malignancy, followed by detailed discussions on the types of head and neck malignancy and their histological classification. The book then provides information about specialized topics relevant to the specialty of head and neck oncology. Key Features: - Comprehensive coverage of head and neck cancers with topic-based chapters - Introductory text explaining the basics of inflammation - Detailed information on the relationship between inflammation and head and neck neoplasms - Information about the classification of head and neck cancers - Methods for diagnosis and treatment - Special topics such as complications caused by HPV infections, chemoradiation, immune-targeted therapy, and inflammatory biomarkers - References for further reading The combination of basic and advanced topics makes this book an informative reference for medical students and professionals at all levels. Residents specializing in otolaryngology, oncology, and surgery as well as researchers studying inflammation will also gain an understanding of the subject in relation to oncogenesis.

Head And Neck Malignancy Highlights Of Clinical Presentation Assessment And Treatment

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Author : Norhafiza Mat Lazim, Zul Izhar Mohd Ismail, Baharudin Abdullah
language : en
Publisher: Penerbit USM
Release Date : 2023-11-21

Head And Neck Malignancy Highlights Of Clinical Presentation Assessment And Treatment written by Norhafiza Mat Lazim, Zul Izhar Mohd Ismail, Baharudin Abdullah and has been published by Penerbit USM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-21 with Medical categories.

Head and neck cancer is on the rise, affecting the adult and paediatric patients. Its treatment is challenging and is governed by numerous factors, especially tumour biology, patient demographic and availability of efficient treatment regimes. The prognosis of head and neck cancer is dismal despite multimodality treatment. This is largely due to late presentation of the disease, as well as poor compliance to treatment and suboptimal treatment approaches. The prognosis and survival rate of head and neck cancer patients can be enhanced with a thorough understanding of the disease, effective communication between in charge clinician, collaborative effort of multiple expertise involving in the management of case, and a refined treatment plan and implementation. Of note, early screening and effective preventive measures will lessen the head and neck tumour burden worldwide. The identification of critical risk factors such as the oncogenic viruses (HPV, EBV), environmental and chemical carcinogen, and dietary factor allow identification of at-risk population, hence early intervention can be instituted. Many of head and neck cancer involves with critical function of human life such as swallowing, breathing, speech, olfaction, hearing and vision. Thus, surgical treatment of this tumour can result in significant sequalae that can impair patients’ quality of life. Imperatively postoperative chemoradiation can further exacerbate the complications with resultant fibrosis, polyneuropathy, fatigue, and many more. Escalation of therapeutic approaches and multiteam management is crucial for the betterment of head and neck cancer patients’ care.

Tumor Microenvironments In Organs

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Author : Alexander Birbrair
language : en
Publisher: Springer Nature
Release Date : 2020-02-06

Tumor Microenvironments In Organs written by Alexander Birbrair and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-06 with Science categories.

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more. Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

The Physics Of Cancer

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Author : Caterina A. M. La Porta
language : en
Publisher: Cambridge University Press
Release Date : 2017-04-20

The Physics Of Cancer written by Caterina A. M. La Porta and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-20 with Science categories.

An introduction to the emerging field of cancer physics, integrating cancer biology with approaches from theoretical and applied physics.

Microbiome And Cancer

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Author : Erle S. Robertson
language : en
Publisher: Springer
Release Date : 2019-02-20

Microbiome And Cancer written by Erle S. Robertson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-20 with Medical categories.

This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues.

Signal Transduction In Cancer

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Author : David A. Frank
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-12-31

Signal Transduction In Cancer written by David A. Frank and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-31 with Medical categories.

One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

Tumor Cell Metabolism

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Author : Sybille Mazurek
language : en
Publisher: Springer
Release Date : 2015-01-19

Tumor Cell Metabolism written by Sybille Mazurek and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-19 with Medical categories.

The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagnostic development, as well as for clinicians and oncologists.

Rediscovering Cancer

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Author : Sayali Mukherjee
language : en
Publisher: Apple Academic Press
Release Date : 2018-05-15

Rediscovering Cancer written by Sayali Mukherjee and has been published by Apple Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-15 with categories.

This volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells. Rediscovering Cancer: From Mechanism to Therapy also includes some recent research on the therapeutic aspects of cancer. Chapters related to immunotherapy, chemotherapy, and use of chitosan-based nanoparticles for cancer therapy are included, with emphasis on preventive measures for cancer. Overall, this informative volume covers the present knowledge and future direction on the field of cancer research.

Memory S Last Breath

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Author : Gerda Saunders
language : en
Publisher: Hachette UK
Release Date : 2017-06-13

Memory S Last Breath written by Gerda Saunders and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-13 with Family & Relationships categories.

A "courageous and singular book" (Andrew Solomon), Memory's Last Breath is an unsparing, beautifully written memoir -- "an intimate, revealing account of living with dementia" (Shelf Awareness). Based on the "field notes" she keeps in her journal, Memory's Last Breath is Gerda Saunders' astonishing window into a life distorted by dementia. She writes about shopping trips cut short by unintentional shoplifting, car journeys derailed when she loses her bearings, and the embarrassment of forgetting what she has just said to a room of colleagues. Coping with the complications of losing short-term memory, Saunders, a former university professor, nonetheless embarks on a personal investigation of the brain and its mysteries, examining science and literature, and immersing herself in vivid memories of her childhood in South Africa. "For anyone facing dementia, [Saunders'] words are truly enlightening . . . Inspiring lessons about living and thriving with dementia." -- Maria Shriver, NBC's Today Show