Heat Shock Protein 90 In Human Diseases And Disorders
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Heat Shock Protein 90 In Human Diseases And Disorders
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Author : Alexzander A. A. Asea
language : en
Publisher: Springer Nature
Release Date : 2019-11-04
Heat Shock Protein 90 In Human Diseases And Disorders written by Alexzander A. A. Asea and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-04 with Science categories.
The book Heat Shock Protein 90 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP90. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, previously unknown signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding Oncogenic Aspects of HSP90; Section II, focuses on Bimolecular Aspects of HSP90; Section III, emphasizes and HSP90 in Natural Products Development and Section IV; give the most up to date reviews on Clinical Aspects of HSP90. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Natural Products, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Heat Shock Protein 90 In Human Diseases And Disorders
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Author :
language : en
Publisher:
Release Date : 2019
Heat Shock Protein 90 In Human Diseases And Disorders written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.
The book Heat Shock Protein 90 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP90. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, previously unknown signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding Oncogenic Aspects of HSP90; Section II, focuses on Bimolecular Aspects of HSP90; Section III, emphasizes and HSP90 in Natural Products Development and Section IV; give the most up to date reviews on Clinical Aspects of HSP90. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Natural Products, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Heat Shock Proteins In Signaling Pathways
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Author : Alexzander A. A. Asea
language : en
Publisher: Springer
Release Date : 2019-07-09
Heat Shock Proteins In Signaling Pathways written by Alexzander A. A. Asea and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-09 with Science categories.
Signaling pathways is a comprehensive mechanism by which all cellular organisms communicate internally and externally with their microenvironment. This is a highly complex and exact process. Errors in signaling pathways and in the processing of cellular information are known to be responsible for the majority of diseases including cancer, inflammatory and neurological disorders. Knowledge gained from the better understanding of signaling pathways will help in elucidating disease processes and will assist in development and design of novel targeted treatment therapies to combat human diseases and disorders. Heat shock proteins (HSP) are uniquely involved in a number of critical signaling pathways. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Heat Shock Proteins In Cancer
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Author : Stuart K. Calderwood
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-09
Heat Shock Proteins In Cancer written by Stuart K. Calderwood and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-09 with Medical categories.
Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
Heat Shock Protein Based Therapies
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Author : Alexzander A.A. Asea
language : en
Publisher: Springer
Release Date : 2015-07-22
Heat Shock Protein Based Therapies written by Alexzander A.A. Asea and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-22 with Medical categories.
The book Heat Shock Protein-Based Therapies provides the most up-to-date review on new heat shock protein-based mechanisms used in the therapy and treatment of various human disorders and diseases, including cancer, muscular atrophy, neurodegenerative disorders (Alzheimer's Disease, Multiple Sclerosis) and infectious diseases (HIV, periodontal disease). Written by leaders in the field of heat shock protein research, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which mechanisms dependent on heat shock proteins are targeted. The chapters also provide answers as to HSP biological significance to the host. This book is a must read for graduate and postgraduates in the field of Drug Development, Biotechnology, Pharmaceutical Industry, Phytomedicine, Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Oncology, Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology.
Heat Shock Proteins And Whole Body Physiology
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Author : Alexzander A. A. Asea
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-10
Heat Shock Proteins And Whole Body Physiology written by Alexzander A. A. Asea and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-10 with Medical categories.
Heat Shock Proteins and Whole Body Physiology is an exciting new book in the Heat Shock Proteins series which provides the most up-to-date review on novel mechanisms insights into the important role played by heat shock proteins in human physiology. Written by leaders in the field of heat shock protein exercise physiology, neuroscience and aging, the chapters systematically and in a step wise fashion takes the reader through the fascinating mechanisms by which heat shock proteins modulate human disease and pathophysiology and provides answers as to its biological significance to the host. Section I, introduces the readers to the role played by heat shock proteins in various diseases and disorders (Heat Shock Proteins and Disease). Section II, addresses the role heat shock proteins play in psychological disorders including post traumatic stress disorders and learning (Heat Shock Proteins and Psychological Stress). Section III, present a detailed review of the role played by heat shock proteins in exercise physiology (Heat Shock Proteins and Exercise Physiology). This book is a must read for heat shock protein researchers, graduate and postgraduate fellows in the field of Medicine in general and specialities in Excersie Physiology, Neuroscience, Immunology, Aging and Pathology.
Heat Shock Proteins In The Immune System
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Author : Robert J. Binder
language : en
Publisher: Springer
Release Date : 2018-04-09
Heat Shock Proteins In The Immune System written by Robert J. Binder and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-09 with Medical categories.
Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system. This one-stop resource contains numerous images to both help illustrate the research on heat shock proteins, and better clarify the field for the non-expert. Heat shock proteins (HSPs) were discovered in 1962 and were quickly recognized for their role in protecting cells from stress. Twenty years later, the immunogenicity of a select few HSPs was described, and for the past 30 years, these findings have been applied to numerous branches of immunology, including tumor immunology and immunosurveillance, immunotherapy, etiology of autoimmunity, immunotherapy of infectious diseases, and expression of innate receptors. While HSPs can be used to manipulate immune responses by exogenous administration, they appear to be involved in initiation of de novo immune responses to cancer and likely in the maintenance of immune homeostasis.
Regulation Of Heat Shock Protein Responses
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Author : Alexzander A A Asea
language : en
Publisher: Springer
Release Date : 2019-01-08
Regulation Of Heat Shock Protein Responses written by Alexzander A A Asea and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-08 with Medical categories.
This books provides the most up-to-date reviews on current advances in our understanding of the regulation of heat shock protein responses. Key basic scientists and clinical research laboratories from major universities, academic medical centers and pharmaceutical companies around the world have contributed chapters that review present research activity and importantly project this field into the future. For easy readability, the book is sub divided into four sections, including, Section I - HSP and Stress Responses; Section II - Chaperone Functions of HSP; Section III - HSP in Human Diseases; Section IV - Prognosis & Diagnosis of HSP. The book is a must read for researchers involved in biomedical research, drug discovery and design to improve human health.
Heat Shock Proteins In Neuroscience
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Author : Alexzander A. A. Asea
language : en
Publisher: Springer Nature
Release Date : 2019-10-30
Heat Shock Proteins In Neuroscience written by Alexzander A. A. Asea and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-30 with Science categories.
The book Heat Shock Proteins in Neuroscience provides the most comprehensive review on contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding of Neurological Aspects of HSP; Section II, focuses on Aspects of HSP in Neurodegenerative Diseases and Disorders, Section III, emphasizes the importance of HSP in Multiple Sclerosis; Section IV, reviews critical Aspects of HSP in Alzheimer’s Disease and Section V, gives a comprehensive update of the Development of HSP-Based Therapies for Neurological Disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Neurology and Neurosciences, Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Hsp90 In Cancer Beyond The Usual Suspects
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-02-23
Hsp90 In Cancer Beyond The Usual Suspects written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-23 with Science categories.
Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. Focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins Highlights the rapidly evolving understanding of the fundamental roles of Hsp90 in cancer biology Discusses the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression