Helicobacter Pylori Infection And Immunity
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Helicobacter Pylori Infection And Immunity
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Author : Yoshimasa Yamamoto
language : en
Publisher:
Release Date : 2001-12-01
Helicobacter Pylori Infection And Immunity written by Yoshimasa Yamamoto and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-12-01 with categories.
Helicobacter Pylori In The 21st Century
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Author : Philip Sutton
language : en
Publisher: CABI
Release Date : 2010
Helicobacter Pylori In The 21st Century written by Philip Sutton and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.
Helicobacter Pylori
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Author : Shawna L. Fleming
language : en
Publisher: Infobase Publishing
Release Date : 2007
Helicobacter Pylori written by Shawna L. Fleming and has been published by Infobase Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Describes the symptoms and effects of helicobacter pylori infections--the leading cause of stomach ulcers--the role of the bacteria in harboring other diseases, how they affect digestion, and treatment options.
Molecular Mechanisms Of Inflammation Induction Resolution And Escape By Helicobacter Pylori
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Author : Steffen Backert
language : en
Publisher: Springer
Release Date : 2019-05-23
Molecular Mechanisms Of Inflammation Induction Resolution And Escape By Helicobacter Pylori written by Steffen Backert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-23 with Medical categories.
This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world’s population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.
Immunology Of Helicobacter Pylori Infection
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Author : Darmadi Darmadi
language : en
Publisher:
Release Date : 2020
Immunology Of Helicobacter Pylori Infection written by Darmadi Darmadi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Electronic books categories.
Helicobacter pylori (H. pylori) is the most common infecting microorganism in humans. H. pylori had coexisted with humans for 30,000 years ago and developed extensive survival adaptations. The infection is both active and chronic and leads to several disorders from chronic gastritis to gastric adenocarcinoma. The prevalence of H. pylori infection is still high in developing countries. The burden of disease due to infection is also heavy. The persistence of infection is the basis of diseases. H. infection activates innate and adaptive immune responses but the immune response fails to eradicate the infection. H. pylori is able to evade both innate and adaptive immune responses. It can neutralize gastric acid, elicit autoimmunity toward parietal cells, prevent phagocytosis, induce apoptosis of immune cells, inhibit lymphocyte proliferation, disrupt imbalance between humoral and cellular adaptive immune responses, promote regulatory T cell activity, and trigger genetic rearrangement. Host factor is involved in the incidence of H. pylori infection and its complications. Reinfection after eradication is common. Multiple drug resistance has also emerged. Vaccination is a promising management approach to eradicate H. pylori and prevent diseases it caused. The development of the vaccine itself needs to consider the immune escape mechanism of H. pylori.
The Effect Of Helicobacter Pylori On Innate Immunity
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Author : Michelle Ang
language : en
Publisher:
Release Date : 2010
The Effect Of Helicobacter Pylori On Innate Immunity written by Michelle Ang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
The innate immune system is important in both acute and chronic infection. In this thesis, I investigated the effect of H. pylori infection on 1) DCs, key orchestrators of the immune system, and 2) autophagy, recently identified as an important component of innate immunity. I determined that H. pylori activates the STAT3 pathway in DCs, increasing DC maturation and inducing production of IL-10, IL-12p40 and TNF-alpha, without IL-12p70. This cytokine profile may favour an immunoregulatory response, promoting persistent H. pylori infection. In addition I determined that H. pylori's VacA toxin induced autophagy, ROS production and Parkin aggregation which has been implicated in mediating autophagy in response to mitochondrial damage. Thus H. pylori alters these key effectors of innate immunity which may play a role in promoting its chronic infection and disease.
Helicobacter Pylori
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Author : Bruna Maria Roesler
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-09-18
Helicobacter Pylori written by Bruna Maria Roesler and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-18 with Science categories.
Helicobacter pylori is an universally distributed bacterium which affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacteria and great studies and discussions about all its aspects are welcome to the medical and scientific communities.
Helicobacter Pylori Infection And Immunity
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Author : Sukanya Raghavan
language : en
Publisher:
Release Date : 2002
Helicobacter Pylori Infection And Immunity written by Sukanya Raghavan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
Towards The Eradication Of Helicobacter Pylori Infection Rapid Diagnosis And Precision Treatment
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Author : Liang Wang
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-05-15
Towards The Eradication Of Helicobacter Pylori Infection Rapid Diagnosis And Precision Treatment written by Liang Wang and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-15 with Medical categories.
"Towards the Eradication of Helicobacter pylori Infection - Rapid Diagnosis and Precision Treatment" book is a comprehensive guide to combating one of the most persistent challenges in global public health. In this volume, experts from various disciplines have joined forces to present the latest research, clinical insights, and practical applications for diagnosing and treating H. pylori infection. The chapters present in this volume cover diagnostic modalities in detecting H. pylori infection, from rapid noninvasive techniques for detecting antibiotic resistance to the utility of linked color imaging in endoscopic diagnosis. The book also presents innovative treatment strategies, including the role of cytokines in inflammation, the impact of antibiotic resistance patterns, and the potential of immunotherapeutic approaches. Healthcare professionals, researchers, and students should benefit from this volume in developing the knowledge and tools necessary to combat and eradicate H. pylori infection effectively.
Helicobacter Pylori
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Author : R.H. Hunt
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Helicobacter Pylori written by R.H. Hunt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Helicobacter pylori has attracted widening interest from basic scientists and clinical investigators and the information on this organism is increasing exponentially. It is now accepted that H. Pylori is the most important cause of chronic active gastritis. Furthermore, data have confirmed a marked reduction in the relapse rate of both duodenal and gastric ulcer after eradication of the organism. These important clinical observations have served as a strong stimulus to the investigation of the basic mechanisms involved in the pathogenesis of H. pylori-associated inflammation and the subsequent alterations of gastroduodenal function and gastric mucosal architecture. The book contains chapters by a multidisciplinary, international group of basic scientists and clinical investigators who focus on various microbiological aspects of H. pylori, on the role of H. pylori in peptic ulcer and gastric cancer, and the current status of therapy. The book contains the proceedings of the conference on `Helicobacter pylori: Basic Mechanisms to Clinical Cure', held at Amelia Island, Florida, U.S.A., on November 3--6, 1993.