Heme Biology Heme Acts As A Versatile Signaling Molecule Regulating Diverse Biological Processes Second Edition
DOWNLOAD
Download Heme Biology Heme Acts As A Versatile Signaling Molecule Regulating Diverse Biological Processes Second Edition PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Heme Biology Heme Acts As A Versatile Signaling Molecule Regulating Diverse Biological Processes Second Edition book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Heme Biology Heme Acts As A Versatile Signaling Molecule Regulating Diverse Biological Processes Second Edition
DOWNLOAD
Author : Li Zhang
language : en
Publisher: World Scientific
Release Date : 2020-02-18
Heme Biology Heme Acts As A Versatile Signaling Molecule Regulating Diverse Biological Processes Second Edition written by Li Zhang and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-18 with Science categories.
This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction of the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. In the second edition, a new chapter is devoted to describe findings about heme uptake, transport, and trafficking of heme synthesis intermediates in mammals. Additionally, a chapter about the newly discovered roles of elevated heme biosynthesis and uptake in lung tumorigenesis is included.Heme Biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to know about the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.
Heme Biology
DOWNLOAD
Author : Li Zhang (Biological science professor)
language : en
Publisher: World Scientific
Release Date : 2020
Heme Biology written by Li Zhang (Biological science professor) and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Heme categories.
"This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction of the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. In the second edition, a new chapter is devoted to describe findings about heme uptake, transport, and trafficking of heme synthesis intermediates in mammals. Additionally, a chapter about the newly discovered roles of elevated heme biosynthesis and uptake in lung tumorigenesis is included. Heme Biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to know about the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm"--Publisher's website.
Heme Biology The Secret Life Of Heme In Regulating Diverse Biological Processes
DOWNLOAD
Author : Li Zhang
language : en
Publisher: World Scientific
Release Date : 2011-07-19
Heme Biology The Secret Life Of Heme In Regulating Diverse Biological Processes written by Li Zhang and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-19 with Science categories.
This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction to the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. Finally, an up-to-date review of human diseases associated with heme synthesis and application of heme synthesis in photodynamic therapy in cancer treatment is presented.Heme biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to comprehend the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.
Molecular Biology Of The Cell
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2004
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.
Acth Action In The Adrenal Cortex From Molecular Biology To Pathophysiology
DOWNLOAD
Author : Nicole Gallo-Payet
language : en
Publisher: Frontiers Media SA
Release Date : 2017-07-27
Acth Action In The Adrenal Cortex From Molecular Biology To Pathophysiology written by Nicole Gallo-Payet and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-27 with ACTH. categories.
By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and function, the various intracellular signaling cascades, which involve not only protein kinase A, the key mediator of ACTH action, but also phosphatases, phosphodiesterases, ion channels and the cytoskeleton. The importance of the proteins involved in the cell detoxification is also considered, in particular the effect that ACTH has on protection against reactive oxygen species generated during steroidogenesis. The impact of the cellular microenvironment, including local production of ACTH is discussed, both as an important factor in the maintenance of homeostasis, but also in pathological situations, such as severe inflammation. Finally, the Research Topic reviews the role that the pituitary-adrenal axis may have in the development of metabolic disorders. In addition to mutations or alterations of expression of genes encoding components of the steroidogenesis and signaling pathways, chronic stress and sleep disturbance are both associated with hyperactivity of the adrenal gland. A resulting effect is increased glucocorticoid secretion inducing food intake and weight gain, which, in turn, leads to insulin and leptin resistance. These aspects are described in detail in this Research Topic by key investigators in the field. Many of the aspects addressed in this Research Topic still represent a stimulus for future studies, their outcome aimed at providing evidence of the central position occupied by the adrenal cortex in many metabolic functions when its homeostasis is disrupted. An in-depth investigation of the mechanisms underlying these pathways will be invaluable in developing new therapeutic tools and strategies.
Diversity Oriented Synthesis
DOWNLOAD
Author : Andrea Trabocchi
language : en
Publisher: John Wiley & Sons
Release Date : 2013-06-17
Diversity Oriented Synthesis written by Andrea Trabocchi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-17 with Science categories.
Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.
Energy Research Abstracts
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1992
Energy Research Abstracts written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Power resources categories.
Peptide Protein And Enzyme Design
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2016-08-27
Peptide Protein And Enzyme Design written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-27 with Science categories.
De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction. - Continues the legacy of this premier serial with quality chapters on de novo enzyme design - Represents the newest volume in the Methods in Enzymology series, providing premier, quality chapters authored by leaders in the field - Ideal reference for those interested in the study of enzyme design that looks at both structure and mechanism
Tetrapyrroles
DOWNLOAD
Author : Martin Warren
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-21
Tetrapyrroles written by Martin Warren and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-21 with Science categories.
Excluding the biological polymers proteins, lipids and nucleic acids, modified tetrapyrroles are the biological molecules that have had the greatest impact on the evolution of life over the past 4 billion years. They are involved in a wide variety of fundamental processes that underpin central primary metabolism in all kingdoms of life, from photosynthesis to methanogenesis. Moreover, they bring colour into the world and it is for this reason that these compounds have been appropriately dubbed the ‘pigments of life’. To understand how and why these molecules have been so universally integrated into the life processes one has to appreciate the chemical properties of the tetrapyrrole scaffold and, where appropriate, the chemical characteristics of the centrally chelated metal ion. This book addresses why these molecules are employed in Nature, how they are made and what happens to them after they have finished their usefulness.
Cumulated Index Medicus
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1999
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medicine categories.