Herpesvirus Transcription And Its Regulation
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Herpesvirus Transcription And Its Regulation
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Author : Edward K. Wagner
language : en
Publisher: CRC Press
Release Date : 1991-01-03
Herpesvirus Transcription And Its Regulation written by Edward K. Wagner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-01-03 with Medical categories.
The herpesviruses are arguably the most successful animal viruses, and nearly 100 distinct examples have been described. Currently, a number of active research groups throughout the world are making important contributions concerning the precise molecular nature of herpesvirus transcripts, the proteins they encode, and the viral and host factors responsible for the control of their expression. Herpesvirus Transcription and Its Regulation describes current programs in a number of leading laboratories and emphasizes the research regarding herpes simplex virus type 1, due primarily to its importance in herpesvirus research. However, several other well-characterized herpesviruses are also described. New research areas covered include molecular analyses of herpesvirus regulatory functions and herpes simplex virus latent phase gene expression. This volume is a timely guide for established research workers and advanced students currently engaged in research on animal virology, viral pathogenesis, and virus-host interactions.
Transcriptional Regulation By The Human Herpesvirus Hhv 8 Lytic Transcription Factors Virf 1 And Rta
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Author : Florence Roan
language : en
Publisher:
Release Date : 2001
Transcriptional Regulation By The Human Herpesvirus Hhv 8 Lytic Transcription Factors Virf 1 And Rta written by Florence Roan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Human Herpesviruses
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Author : Ann Arvin
language : en
Publisher: Cambridge University Press
Release Date : 2007-08-16
Human Herpesviruses written by Ann Arvin and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-16 with Medical categories.
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Latency Strategies Of Herpesviruses
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Author : Janos Minarovits
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-12-13
Latency Strategies Of Herpesviruses written by Janos Minarovits and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Medical categories.
This volume provides an overview of the latency strategies developed during the estimated 200,000 year-long coevolution of Alpha-, Beta- and Gammaherpesvirinae and their host species. While the main emphasis is on herpesviruses infecting humans, relevant cases if herpesviruses infecting animals are covered as well. Special emphasis is given to results on molecular mechanisms regulating latent promoters of herpesvirus genomes and signals and molecular pathways resulting in reactivation of latent viral genomes.
Herpesviruses And Immunity
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Author : Peter G. Medveczky
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Herpesviruses And Immunity written by Peter G. Medveczky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Science categories.
Although virology and immunology are now considered separate disciplines, history shows that these areas ofinvestigation always overlapped and one cannot really exist without the other. This trend has become particularly significant and fruitful in the past few years in the area of herpesvirus research. The genomes of the most important herpesviruses have been sequenced, a significant portion of their genes have been identified, and many secrets of regulation of gene expr- sion have been unraveled. Now this progress sets the stage for a true revolution in herpesvirus research: analysis of interactions between the host and the virus. Because herpesviruses can induce, suppress, and fool the immune system, the most productive herpesvirologists are also expert immunologists, and the current results ofthis interdisciplinary effort are truly remarkable. Because herpesviruses cause many important human diseases, the devel- ment of vaccines against these agents is a very significant goal. This effort is also very challenging because of the complexity of herpesviruses and the lack of sufficient information about immune responses. The remarkable ability of herpesviruses to escape immune responses is - other feature that brings immunology and virology together. Herpesviruses - code many proteins that interact with and down-regulate some key elements of the immune system. Thisproperty of herpesviruses represents amajor challenge in developing strategies against these viruses. On the positive side, these viral proteins also provide novel tools for analyzing specific immune reactions and molecular mechanisms.
Pathogenicity Of Human Herpesviruses Due To Specific Pathogenicity Genes
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Author : Yechiel Becker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pathogenicity Of Human Herpesviruses Due To Specific Pathogenicity Genes written by Yechiel Becker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Six members of the Herpesviridae family are human pathogens, including herpes and 2 (HSV-I and 2), Epstein-Barr virus (EBV), varicella zoster simplex virus I virus (VZV), human cytomegalovirus (HCMV), and human herpesvirus 6 (HHV 6). Each of these viruses is capable of causing distinct diseases of varying severity in children, young adults, and the aged. The diseases range from infection of epithelial tissue to the infection of internal organs and white blood cells. A common feature of the six pathogenic human herpesviruses is their ability to latently infect different cell types in which the viral DNA is not integrated and is unable to express its pathogenicity. Reactivation of the herpesviruses is a result of cellular processes which reactivate viral genes, leading to virus progeny and to signs of infection. Due to their ability to become latent after initial infection, once the pathogenic herpesviruses infect children they are maintained throughout life, having the potential of cause various diseases upon reactivation.
Interactions Between Retroviruses And Herpesviruses
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Author : Hsing-Jien Kung
language : en
Publisher: World Scientific
Release Date : 1994
Interactions Between Retroviruses And Herpesviruses written by Hsing-Jien Kung and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Retroviruses and herpesviruses are two important human pathogens. Together, they occupy one of the most important places in modern Medical Virology. Coinfections of these two viruses in the same individuals are frequently observed, especially in patients afflicted with AIDS. Potential consequences of such interactions include the exacerbation of the disease, changing of the disease courses and the release of new viruses, etc. An understanding of the underlying mechanism is important, but, thus far, few insights have been gained. The present monograph, arranged in eight chapters, is intended to provide an updated and concise review of recent works regarding the molecular and cellular mechanisms of such interactions. The topics covered range from transcriptional regulation, receptor modulation, genetic recombination, to AIDS and oncogenesis. Human immunodeficiency virus, avian leukosis virus, reticuloendotheliosis virus, herpes simplex virus, cytomegalovirus, herpesvirus-6 and Marek's disease virus are among the viruses discussed. The contributing authors are among the leaders in this field and are responsible for many of the original discoveries presented. This should serve as a valuable research and teaching reference for both beginning and advanced researchers in virology and oncology.
Herpes Simplex Virus
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Author : Barry T. Rouse
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Herpes Simplex Virus written by Barry T. Rouse and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control. The virus is large and complex, coding for 70 or more proteins. Although many mysteries remain to be unraveled, our knowledge base regarding genomic organization, gene expression and regulation, pathogenesis, and immune recog nition of component parts is quite considerable. Indeed, meet ings devoted entirely to herpesviruses are conspicuous by their frequency and excellent, yet sometimes exclusive, attendance. The purpose of this volume is to compile in a single book a series of reviews by leading investigators that deal with various aspects of virus-host interactions and which hopefully will pro vide clues as to how to best manage HSV from an immunobio logical perspective. Ultimately, one anticipates that a full under standing of virus-host interaction will lead to strategies useful for the prevention and control of HSV. The state of current progress with conventional vaccines is presented, as is a chapter on intracellular immunization. This latter novel approach to virus infections comes at approximately the bicentenary of Jenner's introduction of a successful conventional immunization strategy.
Dna Replication In Eukaryotic Cells
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Author : Melvin L. DePamphilis
language : en
Publisher: CSHL Press
Release Date : 1996
Dna Replication In Eukaryotic Cells written by Melvin L. DePamphilis and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
National Institutes of Health. Cold Spring Harbor Monograph, Volume 31 Extensive text on the replication of DNA, specifically in eukaryotic cells, for researchers. 68 contributors, 54 U.S.
Alpha Herpesviruses
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Author : Rozanne M. Sandri-Goldin
language : en
Publisher: Caister Academic Press Limited
Release Date : 2006
Alpha Herpesviruses written by Rozanne M. Sandri-Goldin and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Science categories.
The alpha herpesviruses are an important group of viruses characterized by a short reproductive cycle, rapid destruction of the host cell, and the ability to replicate in a wide variety of host tissues. A key attribute of these viruses is the ability to establish lifelong latent infection in the peripheral nervous system of the natural host. Research into the molecular and cellular biology of the alpha herpesviruses has advanced greatly in recent years. Written by internationally recognized experts, this book highlights the more provocative and exciting findings in herpesvirus research. Each chapter is a review of a specific area with an emphasis on recent advances and the latest developments. The book examines multifunctional proteins, advances in DNA replication, new information on the regulation of gene expression, the emergence of new technologies, recent technological advances in fluorescent probes, the induction of apoptosis, the disruption of interferon, vaccine development, and drug design. With a specific focus on new and topical herpesvirus research, Alpha Herpesviruses is essential reading for everyone with an interest in herpesviruses and it is recommended reading for other scientists working in viral pathogenesis, viral genomics, and antiviral research.