High Solid Dispersions


High Solid Dispersions
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High Solid Dispersions


High Solid Dispersions
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Author : Michel Cloitre
language : en
Publisher: Springer
Release Date : 2011-04-08

High Solid Dispersions written by Michel Cloitre and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-08 with Technology & Engineering categories.


From Polymers to Colloids: Engineering the Dynamic Properties of Hairy Particles, by D. Vlassopoulos and G. Fytas * Nonlinear Rheological Properties of Dense Colloidal Dispersions Close to a Glass Transition Under Steady Shear, by M. Fuchs * Micromechanics of Soft Particle Glasses, by R. T. Bonnecaze and M. Cloitre * Quantitative Imaging of Concentrated Suspensions Under Flow, by L. Isa, R. Besseling, A. B. Schofield and W. C. K. Poon * Soft and Wet Materials: From Hydrogels to Biotissues, by J. P. Gong and Y. Osada



High Solid Dispersions


High Solid Dispersions
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Author : Michel Cloitre
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-28

High Solid Dispersions written by Michel Cloitre and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-28 with Technology & Engineering categories.


From Polymers to Colloids: Engineering the Dynamic Properties of Hairy Particles, by D. Vlassopoulos and G. Fytas * Nonlinear Rheological Properties of Dense Colloidal Dispersions Close to a Glass Transition Under Steady Shear, by M. Fuchs * Micromechanics of Soft Particle Glasses, by R. T. Bonnecaze and M. Cloitre * Quantitative Imaging of Concentrated Suspensions Under Flow, by L. Isa, R. Besseling, A. B. Schofield and W. C. K. Poon * Soft and Wet Materials: From Hydrogels to Biotissues, by J. P. Gong and Y. Osada



Amorphous Solid Dispersions


Amorphous Solid Dispersions
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Author : Navnit Shah
language : en
Publisher: Springer
Release Date : 2014-11-21

Amorphous Solid Dispersions written by Navnit Shah and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-21 with Medical categories.


This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future.



Recent Progress In Solid Dispersion Technology


Recent Progress In Solid Dispersion Technology
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Author : Kohsaku Kawakami
language : en
Publisher: MDPI
Release Date : 2019-10-01

Recent Progress In Solid Dispersion Technology written by Kohsaku Kawakami and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-01 with Science categories.


Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.



Pharmaceutical Amorphous Solid Dispersions


Pharmaceutical Amorphous Solid Dispersions
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Author : Ann Newman
language : en
Publisher: John Wiley & Sons
Release Date : 2015-03-09

Pharmaceutical Amorphous Solid Dispersions written by Ann Newman and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-09 with Science categories.


Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations • Has an appendix with structure and property information for polymers commonly used in drug development and with marketed drugs developed using the amorphous sold dispersion approach • Addresses global regulatory issues including USA regulations, ICH guidelines, and patent concerns around the world



Pharmaceutical Solid Dispersion Technology


Pharmaceutical Solid Dispersion Technology
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Author : Muhammad J. Habib
language : en
Publisher: CRC Press
Release Date : 2000-10-05

Pharmaceutical Solid Dispersion Technology written by Muhammad J. Habib and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-05 with Medical categories.


There has not, until now, been a single up-to-date volume to provide those in drug R&D with practical information on all aspects of solid dispersion technology for drugs. This forthcoming volume finally provides such a guide and reference. The unified presentation by a team of specialists in this field is designed for practical application. Theoretical concepts are covered for a fuller understanding of current techniques. All significant recent developments are included.



Design And Evaluation Of Solid Dispersion Of Water Insoluble Drug


Design And Evaluation Of Solid Dispersion Of Water Insoluble Drug
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Author : Vachaspati Dubey
language : en
Publisher:
Release Date : 2016-01-22

Design And Evaluation Of Solid Dispersion Of Water Insoluble Drug written by Vachaspati Dubey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-22 with categories.




5th International Conference On Biomedical Engineering In Vietnam


5th International Conference On Biomedical Engineering In Vietnam
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Author : Vo Van Toi
language : en
Publisher: Springer
Release Date : 2014-11-18

5th International Conference On Biomedical Engineering In Vietnam written by Vo Van Toi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-18 with Technology & Engineering categories.


This volume presents the proceedings of the Fifth International Conference on the Development of Biomedical Engineering in Vietnam which was held from June 16-18, 2014 in Ho Chi Minh City. The volume reflects the progress of Biomedical Engineering and discusses problems and solutions. I aims identifying new challenges, and shaping future directions for research in biomedical engineering fields including medical instrumentation, bioinformatics, biomechanics, medical imaging, drug delivery therapy, regenerative medicine and entrepreneurship in medical devices.



Computational Pharmaceutics


Computational Pharmaceutics
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Author : Defang Ouyang
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-18

Computational Pharmaceutics written by Defang Ouyang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-18 with Science categories.


Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.



Technological Applications Of Dispersions


Technological Applications Of Dispersions
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Author : Robert B. McKay
language : en
Publisher: CRC Press
Release Date : 2020-08-26

Technological Applications Of Dispersions written by Robert B. McKay and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Science categories.


"This comprehensive guide illustrates the effects of dispersions in applications, the means necessary to achieve these effects with optical results, and how to overcome or avoid the difficulties encounteredemphasizing the dispersions of solid particles in liquid or solid media."