Highly Selective Separations In Biotechnology
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Highly Selective Separations In Biotechnology
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Author : G. Street
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Highly Selective Separations In Biotechnology written by G. Street and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Success in meeting the challenge to produce the commercial products anticipated by the exploitation of biological processes depends upon provid ing effective separation protocols. Effectiveness can be measured in terms of selectivity, purity, resolution and validatory success. The major processing problems are associated with either the selective recovery of molecules which are present in low concentrations from complex mixtures or the selective removal of contaminants from the desired molecule. Central to the evolution of processes satisfying this demand are the regulatory requirements being imposed by governments on the purity of a product, especially in the health care market. Synthetic organic chemists are increasingly finding it advantageous to conduct one or more steps using either enzymic biotransformations where molecules with a single and consistent stereochemistry or chirality are required. The underlying princi ples behind the methods, techniques and processes currently being used and developed commercially rely upon the biospecific nature and properties of the desired molecule. When these factors are married to the more traditional techniques of precipitation, chromatography, liquid-liquid extraction and membrane processes, powerful tools emerge, allowing highly selective separations to be designed. The logical extension of these combinations is to apply genetic engineering techniques to influence the separations at a more fundamental and structural level by modifying the target protein at source, during its synthesis, to facilitate its separation in a given, selective manner, leading to the distinct possibility of producing 'designer' separation programmes.
Highly Selective Separations In Biotechnology
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Author : G. Street
language : en
Publisher: Springer Science & Business Media
Release Date : 1994-08-31
Highly Selective Separations In Biotechnology written by G. Street and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-08-31 with Science categories.
Success in meeting the challenge to produce the commercial products anticipated by the exploitation of biological processes depends upon provid ing effective separation protocols. Effectiveness can be measured in terms of selectivity, purity, resolution and validatory success. The major processing problems are associated with either the selective recovery of molecules which are present in low concentrations from complex mixtures or the selective removal of contaminants from the desired molecule. Central to the evolution of processes satisfying this demand are the regulatory requirements being imposed by governments on the purity of a product, especially in the health care market. Synthetic organic chemists are increasingly finding it advantageous to conduct one or more steps using either enzymic biotransformations where molecules with a single and consistent stereochemistry or chirality are required. The underlying princi ples behind the methods, techniques and processes currently being used and developed commercially rely upon the biospecific nature and properties of the desired molecule. When these factors are married to the more traditional techniques of precipitation, chromatography, liquid-liquid extraction and membrane processes, powerful tools emerge, allowing highly selective separations to be designed. The logical extension of these combinations is to apply genetic engineering techniques to influence the separations at a more fundamental and structural level by modifying the target protein at source, during its synthesis, to facilitate its separation in a given, selective manner, leading to the distinct possibility of producing 'designer' separation programmes.
Separations For Biotechnology
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Author :
language : en
Publisher:
Release Date : 1990
Separations For Biotechnology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Biomolecules categories.
Centrifugal Separations In Biotechnology
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Author : Wallace Woon-Fong Leung
language : en
Publisher: Butterworth-Heinemann
Release Date : 2020-03-13
Centrifugal Separations In Biotechnology written by Wallace Woon-Fong Leung and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-13 with Technology & Engineering categories.
Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. - Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry - Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology - Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements - Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more
Ionic Surfactants And Aqueous Solutions
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Author : Juan H. Vera
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2018-07-09
Ionic Surfactants And Aqueous Solutions written by Juan H. Vera and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-09 with Science categories.
Ionic Surfactants and Aqueous Solutions: Biomolecules, Metals and Nanoparticles covers a wide range of subjects related to aqueous systems, from reverse micelles as ion exchangers to the study of micellar phase transfer catalysis for nucleophilic substitution reactions. The diverse background, expertise and professional interests of the contributors to this book give to it a unique richness of approach in topics of relevance for biotechnology and environmental studies. Over sixty publications presenting research results are combined and expanded in this book by some of the original researchers. At a mature age, and at the summit of successful professional careers, they have taken a second look to the state of the art in the fields that they had pioneered. Eva Rodil and Ana Soto, who had their research formation in the group of Professor Alberto Arce at Universidade de Santiago de Compostela, Spain, are presently professors at that university, Maen Husein is a professor at University of Calgary, Canada. Remy Dumortier, Mohammad Khoshkbarchi, Hamid Rabie and Younok Dumortier Shin, are presently active leaders in the industrial world in Canada and the USA. The editors are retired academics from McGill University, Montreal, Canada, and coauthors of the book Classical Thermodynamics of Fluid Systems.
Natural Based Polymers For Biomedical Applications
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Author : Rui L. Reis
language : en
Publisher: Elsevier
Release Date : 2008-08-15
Natural Based Polymers For Biomedical Applications written by Rui L. Reis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-15 with Science categories.
Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering.The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility.Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. - Examines the sources, processing and properties of natural based polymers for biomedical applications - Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality - Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine
Isolation And Purification Of Proteins
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Author : Rajni Hatti-Kaul
language : en
Publisher: CRC Press
Release Date : 2003-02-05
Isolation And Purification Of Proteins written by Rajni Hatti-Kaul and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-02-05 with Medical categories.
This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.
Characterisation Of Porous Solids V
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Author : G. Kreysa
language : en
Publisher: Elsevier
Release Date : 2000-04-11
Characterisation Of Porous Solids V written by G. Kreysa and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-11 with Technology & Engineering categories.
The Fifth International Symposium on the Characterisation of Porous Solids (COPS-V) was held at Heidelberg, Germany, from May 30 to June 2, 1999. About 220 participants from 25 countries enjoyed a very successful meeting with 32 lectures and 155 poster presentations. The Symposium started with a highly stimulating lecture by Sir John Meurig Thomas, Cambridge, highlighting the recent developments in engineering of new catalysts. The following two full sessions were devoted to theory, modelling and simulation which provide the basis for the interpretation of pore structural data of adsorbents and finely dispersed solids. Sessions 2 and 3 focused on the advances in the synthesis and characterisation of highly ordered inorganic adsorbents and carbons. Sessions 4 and 5 addressed important questions with respect to the characterisation of porous solids by sorption measurement and other related techniques. The intensive three-day programme provided a stimulating forum for the exchange of novel research findings, concepts, techniques and materials which are collected in this volume.
Amino Acids Peptides And Proteins
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Author : J S Davies
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31
Amino Acids Peptides And Proteins written by J S Davies and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.
In an ever-increasing domain of activity Amino Acids Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. Volume 29 provides a review of literature published during 1996. Comprising a comprehensive review of significant developments at this biology/chemistry interface each volume opens with an overview of amino acids and their applications. Work on peptides is reviewed over several chapters ranging from current trends in their synthesis and conformational and structural analysis to peptidomimetics and the discovery of peptide-related molecules in nature. The application of advanced techniques in structural elucidation is incorporated into all chapters whilst periodic chapters on metal complexes of amino acids, peptides and beta-lactams extend the scope of coverage. Efficient searching of specialist topics is facilitated by the sub-division of chapters into discrete subject areas allowing annual trends to be monitored. All researchers in the pharmaceutical and allied industries and at the biology/chemistry interface in academia will find this an indispensable reference source.
Introduction To Green Chemistry
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Author : Albert Matlack
language : en
Publisher: CRC Press
Release Date : 2010-04-05
Introduction To Green Chemistry written by Albert Matlack and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-05 with Science categories.
The book covers traditional green chemistry topics, including catalysis, benign solvents, and alternative feedstocks. It also discusses relevant but less frequently covered topics with chapters such as Chemistry of Longer Wear and Population and the Environment. This coverage highlights the importance of chemistry to everyday life and demonstrates the benefits the expanded exploitation of green chemistry can have for society. Copiously illustrated with over 800 figures, this second edition provides an update from the frontiers of the field.