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Hiv Associated Hematological Malignancies


Hiv Associated Hematological Malignancies
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Hiv Associated Hematological Malignancies


Hiv Associated Hematological Malignancies
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Author : Marcus Hentrich
language : en
Publisher: Springer
Release Date : 2016-02-02

Hiv Associated Hematological Malignancies written by Marcus Hentrich and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-02 with Medical categories.


This book presents a general introduction to and review of HIV-associated hematological malignancies, with a special focus on practical management issues. Each of the relevant malignancies is addressed individually, with an overview of treatment approaches, assessment of evidence regarding their efficacy, and discussion of therapeutic controversies. In addition, careful consideration is paid to issues in molecular and clinical pathology, epidemiological aspects, symptomatology, diagnosis, and risk factors. Separate chapters are devoted to autologous and allogeneic stem cell transplantation and to chemotherapy and interactions with antiretroviral agents. Many of the chapters are written by experts who have been instrumental in shifting the balance for people living with HIV and blood cancers. While two decades ago this diagnosis represented a death sentence, advances in treatment have transformed these cancers into often curable conditions. Nevertheless, optimal treatment of hematological malignancies remains a challenge, particularly in patients with severe immunosuppression. This book will be an invaluable source of information for all practitioners in the fields of clinical hematology and medical oncology and HIV medicine.



Hiv Associated Hematological Malignancies


Hiv Associated Hematological Malignancies
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Author : Marcus Hentrich
language : en
Publisher:
Release Date : 2016

Hiv Associated Hematological Malignancies written by Marcus Hentrich and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with AIDS malignancies categories.


This book presents a general introduction to and review of HIV-associated hematological malignancies, with a special focus on practical management issues. Each of the relevant malignancies is addressed individually, with an overview of treatment approaches, assessment of evidence regarding their efficacy, and discussion of therapeutic controversies. In addition, careful consideration is paid to issues in molecular and clinical pathology, epidemiological aspects, symptomatology, diagnosis, and risk factors. Separate chapters are devoted to autologous and allogeneic stem cell transplantation and to chemotherapy and interactions with antiretroviral agents. Many of the chapters are written by experts who have been instrumental in shifting the balance for people living with HIV and blood cancers. While two decades ago this diagnosis represented a death sentence, advances in treatment have transformed these cancers into often curable conditions. Nevertheless, optimal treatment of hematological malignancies remains a challenge, particularly in patients with severe immunosuppression. This book will be an invaluable source of information for all practitioners in the fields of clinical hematology and medical oncology and HIV medicine.



Hiv Htlv I Associated Malignancies


Hiv Htlv I Associated Malignancies
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Author : Joseph A. Sparano
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Hiv Htlv I Associated Malignancies written by Joseph A. Sparano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Infection with the human immunodeficiency virus (HIV) and human T-cell lymphotropic virus type I (HTLV-I) is known to be associated with an increased risk of neoplastic disorders, especially Kaposi's sarcoma and aggressive B-cell lymphoma for the former, and T-cell lymphoma for the latter. The information obtained from the study of these infections has led to remarkable advances in our understanding of the immune system, as well as the biology of human neoplasms. The management of malignant diseases in such patients also poses substantial challenges to clinicians. This book provides an overview of the epidemiology, biology, clinical features, and clinical management of neoplasms occurring in such individuals. It is an important resource for clinicians treating these diseases, and for basic scientists who have an interest in this field.



Cancers In People With Hiv And Aids


Cancers In People With Hiv And Aids
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Author : Robert Yarchoan
language : en
Publisher: Springer
Release Date : 2014-07-10

Cancers In People With Hiv And Aids written by Robert Yarchoan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-10 with Medical categories.


The association between AIDS and cancer was recognized from the beginning of the AIDS epidemic, when the appearance of Kaposi sarcoma in a cluster of young men was one of the first signs of this new disease. It was soon recognized that AIDS was caused by infection with a novel virus (HIV) and that AIDS patients are prone to develop a number of “AIDS-defining” cancers: Kaposi sarcoma, lymphoma, and cervical cancer. The development of effective combination anti-HIV therapy starting around 1996 converted AIDS from a death sentence to a manageable disease and led to dramatic shifts in the epidemic. As this therapy was able to improve immune function in patients, the incidence of most “AIDS-defining” cancers decreased. There is a misconception, however, that AIDS has gone away. In fact, as AIDS patients are living longer, the number of AIDS patients has more than doubled in the United States since 1996, and the AIDS population overall has increased in age. Also, as AIDS patients are less likely to die of other complications, cancer is coming to the forefront as one of the most common causes of death in regions where AIDS drugs are widely available. Moreover, the three “AIDS-defining” cancers are now taking a back seat to a number of other HIV-associated cancers, such as Hodgkin lymphoma, lung cancer, and anal cancer. In the developing world, AIDS-associated cancers are a major public health problem, and in some regions of sub-Saharan Africa, Kaposi sarcoma is the most common tumor in men. In recent years, there has been a vast increase in our understanding of HIV-associated cancers. We now know, for example, that most are caused by other viruses and that the main role of HIV and immunodeficiency is to provide a supportive environment for the viruses to multiply and for the cancers to develop. But there remain a number of unanswered questions and a need for improved prevention and therapy. In the 28 chapters of this book, written by some of the most renowned experts in this field, we present up-to-date information on the cancers associated with HIV infection. The chapters cover the epidemiology of these cancers, their pathogenesis, their clinical presentation, and their treatment. The book will be of value to physicians, other medical professionals, students, and researchers with an interest in AIDS, viral-associated cancers, or HIV-associated malignancies. TABLE OF CONTENTS 1. HIV-associated Cancers: Overview Robert Yarchoan, Thomas Uldrick, Mark Polizotto 2. Epidemiology of AIDS-defining Malignancies William A. Blattner and Rebecca G. Nowak 3. Epidemiology of non-AIDS Defining Malignancies Andrew E. Grulich 4. HIV Cancers in Resource-Limited Regions Sam M. Mbulaiteye 5. Kaposi's Sarcoma-associated Herpesvirus (KSHV) Blossom Damania and Dirk P. Dittmer 6. Epstein Barr Virus (EBV) Lindsey Hutt-Fletcher 7. Human Papillomavirus (HPV) Zhi-Ming Zheng 8. Merkel Cell Polymavirus (MCV) Nicole Fischer and Adam Grundhoff 9. Presentation and Pathogenesis of Kaposi's Sarcoma Corey Casper 10. Management of Kaposi's Sarcoma Susan E. Krown 11. Presentation and Pathogenesis of HIV Lymphomas Richard F. Little, Stefania Pittaluga, Kieron Dunleavy 12. Diffuse Large B-Cell Lymphoma Neel K. Gupta and Lawrence D. Kaplan 13. Burkitt and Burkitt-Like Lymphoma Kishor Bhatia and Sam M. Mbulaiteye 14. Primary Effusion Lymphoma Giovanna Tosato 15. AIDS-related Central Nervous System Lymphoma Jan Davidson-Moncada and Thomas Uldrick 16. Plasmablastic and Other Lymphomas Huan-You Wang, Ida Wong-Sefidan, Erin Reid 17. Hodkin Lymphoma Michele Spina, Rosanna Ciancia, Accursio Augello 18. Multicentric Castelman Disease Mark N. Polizzotto, Thomas S. Uldrick, Robert Yarchoan 19. Cervical Cancer Elizabeth A. Stier 20. Anal Cancer Joel Palefsky 21. Other HPV-Associated Cancers Kristina R. Dahlstrom and Erich M. Sturgis 22. Lung Cancer in HIV Infection Deepthi Mani and David M. Aboulafia 23. Hepattocellular Carcinoma in HIV-positive Patients Massimiliano Berretta, Paolo De Paoli, Umberto Tirelli, Bruno Cacopardo 24. Merkel Cell Carcinoma and Other HIV-associated Skin Cancers Nathalie C. Zeitouni adn Bethany Lema 25. Conjuctival Carcinoma Kenneth O. Simbiri and Erle S. Robertson 26. Malignancies in Children with HIV Infection D. Cristina Stefan 27. cART and Supportive Care Ronald T. Mitsuyasu 28. Stem Cell Transplantation Christine Durand and Richard Ambinder



Aids Related Cancers And Their Treatment


Aids Related Cancers And Their Treatment
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Author : Ellen G. Feigal
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Aids Related Cancers And Their Treatment written by Ellen G. Feigal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.


This book summarizes the etiology, presentation, and treatment of the complex symptoms, infections, and opportunistic cancers of people living with HIV/AIDS. Presents therapies that strike a balance between controlling and eliminating cancer and minimizing the damage to the immune system. Illustrates points with clear and easily read figures,



Cancer Hiv And Aids


Cancer Hiv And Aids
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Author : Valerie Beral
language : en
Publisher: CSHL Press
Release Date : 1991

Cancer Hiv And Aids written by Valerie Beral and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


Published for the Imperial Cancer Research Fund (UK), each issue of the Cancer surveys series provides a comprehensive survey of the present state and future developments in a well-defined area in oncology in which there is current scientific or clinical interest. The invited papers are from leaders



Aids And Malignancies


Aids And Malignancies
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Author : Basil C. Golematis
language : en
Publisher: Wiley
Release Date : 1996-12-16

Aids And Malignancies written by Basil C. Golematis and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-12-16 with Medical categories.


This book explores AIDS and malignancies, specifically the various cancers and malignant diseases that frequently occur in AIDS patients. It examines Kaposi's sarcoma, Non-Hodgkin's lymphoma, and other malignancies. This book provides thorough coverage for physicians and researchers alike. Addresses critical research and clinical issues. Includes chapters devoted to care and treatment of AIDS and HIV patients with malignant diseases.



Aids Associated Viral Oncogenesis


Aids Associated Viral Oncogenesis
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Author : Craig Meyers
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-04

Aids Associated Viral Oncogenesis written by Craig Meyers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-04 with Medical categories.


One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.



Viral And Immunological Malignancies


Viral And Immunological Malignancies
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Author : Paul Volberding
language : en
Publisher: PMPH-USA
Release Date : 2006

Viral And Immunological Malignancies written by Paul Volberding and has been published by PMPH-USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with AIDS (Disease) categories.


The precise relationship between viral infection and malignancy remains an epidemiologic association and the subject of active investigation. Nonmalignant hematologic disorders have a similarly complex relationship with cancer-associated viruses and may offer insight into the pathogenesis of oncogenesis. This book explores the relationships between viral infections, immune impairments and the hematologic and malignant diseases, particularly against the backdrop of the HIV epidemic. By extending the scope to all of viral oncology the editors provide an invaluable resource on tumors related to other viruses other than HIV, particularly carcinomas of the cervix and anus with HPV and tumors of the liver with the various hepatitis viruses.



Molecular Basis For Therapy Of Aids Defining Cancers


Molecular Basis For Therapy Of Aids Defining Cancers
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Author : Dirk P. Dittmer
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-14

Molecular Basis For Therapy Of Aids Defining Cancers written by Dirk P. Dittmer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-14 with Medical categories.


Cancer incidences increase in people living with HIV/AIDS. Over 2 million people currently live with HIV/AIDS in the US. This number will increase as HAART prolongs the average lifespan and as (at least in some states) the number of new HIV infections increase again. As this population ages their incidence rates for cancer will increase, as well. Recently, new rational targets for cancer therapy have emerged. But their application to the care of HIV+ patients is slow, because of concerns about the weakened immune status of the patients, because of possible drug interactions with HAART and because some of the AIDS defining cancer are rare.