Horizontal Transfer Of Vana Mediated Resistance Among Commensal And Streptogramin Resistant Enterococci Derived From Multi Component Food Systems
DOWNLOAD
Download Horizontal Transfer Of Vana Mediated Resistance Among Commensal And Streptogramin Resistant Enterococci Derived From Multi Component Food Systems PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Horizontal Transfer Of Vana Mediated Resistance Among Commensal And Streptogramin Resistant Enterococci Derived From Multi Component Food Systems book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Horizontal Transfer Of Vana Mediated Resistance Among Commensal And Streptogramin Resistant Enterococci Derived From Multi Component Food Systems
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2007
Horizontal Transfer Of Vana Mediated Resistance Among Commensal And Streptogramin Resistant Enterococci Derived From Multi Component Food Systems written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Antibiotics categories.
The enterococci are commensal lactic acid bacteria of the gastrointestinal tract of humans and animals, and are ubiquitous in nature. They have a long history of use as starter cultures in European fermented foods and are used commercially as probiotics. Within the past two decades, vancomycin-resistant enterococci (VRE) have emerged as significant nosocomial pathogens, treatable with few antibiotics. In the US, the agricultural use of virginiamycin, a streptogramin growth promoter, has raised concern regarding cross-resistance among VRE to the clinical streptogramin quinupristin-dalfopristin. Horizontal transfer of antibiotic resistance genes is mediated by aggregation substances and sex pheromones that induce conjugation, but the role of these virulence factors in enterococci of food origin is largely unknown. The potential for enterococci isolated from multi-component creamy deli salads (including macaroni, potato, chicken, and seafood) to harbor and disseminate the high-level vancomycin resistance gene vanA among more virulent native enterococci was investigated. Initial filter mating between a clinical Enterococcus faecalis isolate carrying vanA and a commensal, vancomycin susceptible E. faecium salad recipient that harbored no virulence genes was demonstrated at a frequency of 10-8 per recipient. The rate of secondary transfer of vanA by this transconjugant to both food and animal enterococci carrying the streptogramin resistance genes vatE or vatD and/or the selected virulence genes agg, gelE, cpd, and efa increased three log-fold. In primary and secondary matings, multiple antibiotic resistance patterns increased for all transconjugants. Additionally, expression of vanA in the absence of selective antibiotic pressure was determined by reverse transcriptase-PCR and found to occur in the primary transconjugant but not in the donor. Results demonstrate that foodborne commensal enterococci from multi-component foods can receive and disseminate vanA to food and animal enterococci that harbor streptogramin resistance and/or virulence genes. The potential for transfer events to occur among commensal and virulent enterococci in foods must be considered for the safe use of Enterococcus in starter cultures and probiotics.
Dissertation Abstracts International
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2009
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Dissertations, Academic categories.
Pathogenic Bacteria
DOWNLOAD
Author : Sahra Kırmusaoğlu
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-12-09
Pathogenic Bacteria written by Sahra Kırmusaoğlu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-09 with Science categories.
Pathogenic bacteria are the main problem in hospital- and community-acquired infections. As bacteria continue to develop more resistance to antibiotics, it is imperative to develop antibacterial treatment strategies. Written by experts from all over the world, this book examines pathogenic bacteria and their link to multidrug resistance. Over thirteen chapters, it presents examples of pathogenesis, virulence factors, and treatment strategies.
Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery
DOWNLOAD
Author : Busi Siddhardha
language : en
Publisher: Springer Nature
Release Date : 2020-03-28
Model Organisms For Microbial Pathogenesis Biofilm Formation And Antimicrobial Drug Discovery written by Busi Siddhardha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-28 with Science categories.
This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
Coagulase Negative Staphylococci
DOWNLOAD
Author : Per-Anders Mårdh
language : en
Publisher: Coronet Books
Release Date : 1986
Coagulase Negative Staphylococci written by Per-Anders Mårdh and has been published by Coronet Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Coagulase categories.
Antimicrobial Drug Resistance
DOWNLOAD
Author : Douglas Mayers
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-07-14
Antimicrobial Drug Resistance written by Douglas Mayers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-14 with Medical categories.
This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for bacteria, fungi, protozoa and viruses. We believe that this information will be of value to clinicians, epidemiologists, microbiologists, virologists, parasitologists, public health authorities, medical students and fellows in training. We have endeavored to provide this information in a style which would be accessible to the broad community of persons who are concerned with the impact of drug resistance in our cl- ics and across the broader global communities. Antimicrobial Drug Resistance is divided into Volume 1 which has sections covering a general overview of drug resistance and mechanisms of drug resistance ? rst for classes of drugs and then by individual microbial agents including bacteria, fungi, protozoa and viruses. Volume 2 addresses clinical, epidemiologic and public health aspects of drug resistance along with an overview of the conduct and interpretation of speci? c drug resistance assays. Together, these two volumes offer a comprehensive source of information on drug resistance issues by the experts in each topic.
Bacterial Resistance To Antibiotics
DOWNLOAD
Author : Boyan B. Bonev
language : en
Publisher: John Wiley & Sons
Release Date : 2019-03-14
Bacterial Resistance To Antibiotics written by Boyan B. Bonev and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-14 with Science categories.
AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Bacterial Adaptation To Co Resistance
DOWNLOAD
Author : Santi M. Mandal
language : en
Publisher: Springer Nature
Release Date : 2019-11-17
Bacterial Adaptation To Co Resistance written by Santi M. Mandal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-17 with Technology & Engineering categories.
The proposed book aims to understand the mechanism of survival of microorganisms in response to chemical stress in various ecological niches that suffer direct human intervention, more so the agricultural, domestic and hospital settings. Microbicides (e.g. disinfectants, antiseptics, fungicides, algaecides, insecticides and pesticides) are used rampantly to control undesirable microbes. Insecticides and pesticides are routinely used in agriculture which directly affect the microbial population in farms, orchards and fields. Health care environments are always stressed with disinfectants and antibiotics. It is always probable that microbicide-stressed microorganisms are in a dynamic state, displaced from one niche to the other. Some soil and water borne bacteria or their resistance determinants are also getting prominence in hospital settings after suffering selective pressure from agricides. In order to reveal the survival strategies of microbicidal-resistant microbes, it is of prime importance to know the mode of action of these complete range of microbicides (agricides to antibiotics). The present book intends to address these issues. There will be several chapters dealing with tolerance and cross resistance in microbes and bacteria in particular, dwelling in various niches. Till date, there is no consensus among scientists in theorizing molecular mechanisms to explain bacterial tolerance and their cross resistance to agricides and antibiotics.
Efflux Mediated Antimicrobial Resistance In Bacteria
DOWNLOAD
Author : Xian-Zhi Li
language : en
Publisher: Springer
Release Date : 2016-11-09
Efflux Mediated Antimicrobial Resistance In Bacteria written by Xian-Zhi Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-09 with Medical categories.
This book, written by leading international experts, provides a comprehensive, current examination of transport-mediated antimicrobial resistance. As a particularly powerful mechanism of multidrug resistance, an in-depth examination of efflux pumps is conducted with bacteria of major public health concern including Enterobacteriaceae, Acinetobacter, Neisseria, Pseudomonas, staphylococci, and mycobacteria. The content spans structural biochemistry and transport mechanisms of the major transporter families and considers individual drug efflux systems across various Gram-positive and Gram-negative species. Genomic analysis of efflux pump distribution and their contribution to clinically-relevant resistance are a major focus of the text. Moreover, interplay between drug efflux pumps and other key resistance mechanisms such as intrinsic drug impermeability, inactivation, and target alterations are discussed, as well as their molecular expression-based regulation and physiological functions beyond resistance, involving biofilms, stress response, and pathogenicity. Finally, strategies are addressed to target this drug resistance mechanism with novel antimicrobials or drug inhibitor adjuvants.
Antimicrobial Resistance And Implications For The 21st Century
DOWNLOAD
Author : I.W. Fong
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-15
Antimicrobial Resistance And Implications For The 21st Century written by I.W. Fong and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-15 with Medical categories.
This comprehensive, up-to-date volume defines the issues and offers potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria, viruses including HIV and herpes, parasites and fungi. The chapters explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions.