Hormone Replacement Therapy And Breast Cancer Risk
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Hormone Replacement Therapy And Breast Cancer Risk
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Author : R.D. Mann
language : en
Publisher: CRC Press
Release Date : 1992-07-15
Hormone Replacement Therapy And Breast Cancer Risk written by R.D. Mann and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-07-15 with Medical categories.
This book covers a topic of considerable current interest and presents many of the most significant research findings available to date. Workers at the forefront of research on hormone replacement therapy and the implications for the risk of breast cancer were invited to attend a special Conference at the Royal Society of Medicine in London in September, 1991, where the latest data were presented to a distinguished audience and the implications of this research were discussed. The volume reviews various aspects of HRT and breast cancer, the physiology of the menopause, the current use of HRT in practice, osteoporosis and epidemiology and presents results from a range of European, American and Australian studies on the role of breast cancer and HRT, finishing with an overview of benefits, use and cost-effectiveness and a general summary. The book represents a definitive statement of current knowledge in this field and an informative update on the implications of recent research. It will be a valuable addition of special significance to the libraries of all those concerned with hormone replacement therapy and the study of breast cancer.
The Controversy Over Hormone Replacement Therapy Evaluating Related Risk Of Breast Cancer And Other Diseases
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Author :
language : en
Publisher: Am Cncl on Science, Health
Release Date :
The Controversy Over Hormone Replacement Therapy Evaluating Related Risk Of Breast Cancer And Other Diseases written by and has been published by Am Cncl on Science, Health this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Estrogen Matters
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Author : Carol Tavris
language : en
Publisher: Hachette UK
Release Date : 2018-09-04
Estrogen Matters written by Carol Tavris and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-04 with Health & Fitness categories.
A compelling defense of hormone replacement therapy, exposing the faulty science behind its fall from prominence and empowering women to make informed decisions about their health. For years, hormone replacement therapy (HRT) was hailed as a miracle. Study after study showed that HRT, if initiated at the onset of menopause, could ease symptoms ranging from hot flashes to memory loss; reduce the risk of heart disease, Alzheimer's, osteoporosis, and some cancers; and even extend a woman's overall life expectancy. But when a large study by the Women's Health Initiative announced results showing an uptick in breast cancer among women taking HRT, the winds shifted abruptly, and HRT, officially deemed a carcinogen, was abandoned. Now, sixteen years after HRT was left for dead, Dr. Bluming, a medical oncologist, and Dr. Tavris, a social psychologist, track its strange history and present a compelling case for its resurrection. They investigate what led the public -- and much of the medical establishment -- to accept the Women's Health Initiative's often exaggerated claims, while also providing a fuller picture of the science that supports HRT. A sobering and revelatory read, Estrogen Matters sets the record straight on this beneficial treatment and provides an empowering path to wellness for women everywhere.
Hormone Replacement Therapy And Cancer
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Author : Andrea R. Genazzani
language : en
Publisher: CRC Press
Release Date : 2020-07-26
Hormone Replacement Therapy And Cancer written by Andrea R. Genazzani and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-26 with Medical categories.
The clinical benefits of hormone replacement therapy in women have to be carefully balanced against the possible risks, and a particular theoretical concern relates to risks associated with various forms of female oncology. Because of conflicting reports, gynecologists and oncologists especially need a single, authoritative resource of up-to-date information. Hormone Replacement Therapy and Cancer, published in association with the International Menopause Society, provides the very consensus statement that clinicians need in this difficult and complex area. Many of the world's leading specialists have contributed important chapters that provide state-of-the-art knowledge about the effects of hormones on women and possible cancer risks. The introductory section deals with carcinogenesis, and the other main sections cover HRT and breast cancer, endometrial cancer, colon cancer, melanoma and epithelial ovarian cancer. The concluding chapters discuss the benefits and risks of sp ecific therapies. An authoritative clinical reference with extensive bibliographic references and index, Hormone Replacement Therapy and Cancer covers all aspects of HRT and cancer based on the research available up to June 2001.
Hormone Replacement Therapy And Breast Cancer
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Author : U. S. Department of Health and Human Services
language : en
Publisher: CreateSpace
Release Date : 2013-06-28
Hormone Replacement Therapy And Breast Cancer written by U. S. Department of Health and Human Services and has been published by CreateSpace this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-28 with Medical categories.
In this systematic evidence review, we evaluate data on the relationship between the use of postmenopausal hormone replacement therapy (HRT) and the risk of breast cancer (BCA). The context of this review is in the overall evaluation of postmenopausal hormone replacement therapy as chemoprophylaxis for chronic conditions. The results from this report will be used as part of an overall report on the risks and benefits of hormone replacement therapy for postmenopausal women. Hormone replacement therapy is used in the United States and worldwide to treat symptoms of menopause and to prevent chronic conditions such as osteoporosis. It is one of the most commonly prescribed drugs in the U.S.; a recent survey in the U.S. of postmenopausal women ages 50 to 75 showed that nearly 38% of women were currently using estrogen or hormone replacement therapy (58.7% of those with prior hysterectomy and 19.6% without hysterectomy). A major and as yet unanswered clinical question is whether hormone replacement therapy increases a woman's risk of breast cancer. This issue is a critical one because the use of HRT is prevalent and because breast cancer is a relatively common disease, so that even a small increase in breast cancer in association with hormone use could significantly influence public health. The importance of endogenous estrogen in the development of breast cancer has been evaluated and confirmed in multiple studies of differing methodologies. Studies in animals have shown that breast cancer can be induced by the administration of estrogen. Among humans, some studies have shown that women with increased levels of circulating estrogen are at higher risk for the subsequent development of breast cancer. Other studies have had conflicting findings, and some have shown this relationship in postmenopausal women only. Reproductive events are important risk factors for breast cancer. Those shown to increase risk include early menarche and late menopause, both of which prolong exposure to higher levels of estrogen as well as other reproductive hormones. Other reproductive experiences, such as late age at first pregnancy and nulliparity, increase breast cancer risk. Oopherectomy among premenopausal women is protective against breast cancer, possibly because of reduced exposure to estrogen. Other risk factors also suggest an important role for estrogen in BCA development. In postmenopausal women, obesity, which correlates with increased estrogen levels, is also associated with an increased risk of BCA. Recent studies have also shown that increased bone density, possibly a reflection of lifetime estrogen exposure, is associated with increased rates of breast cancer. Finally, age-adjusted rates of increase in breast cancer incidence slow at menopause when estrogen levels fall. There are several critical key questions to consider when evaluating the research describing the role of exogenous estrogen or estrogen/progesterone in breast cancer development and prognosis. First, is either estrogen alone or estrogen with progesterone associated with a change in breast cancer mortality? Second, does short-term estrogen use increase the risk of breast cancer? The third question, which is most relevant to the use of estrogen to prevent chronic conditions, is whether long-term estrogen increases breast cancer risk. The fourth question, which reflects the current standard of practice, is whether the combination of estrogen and progesterone, either short-term or long-term, increases the risk of breast cancer. Fifth, is current use of estrogen or hormone replacement therapy associated with increased risk of breast cancer? Sixth, are there subpopulations of women who might be at increased risk of breast cancer when using HRT? Finally, because increased breast mammographic density is independently associated with an increase in breast cancer risk, as well as with decreased accuracy of mammography, does estrogen or estrogen/progestins change breast density?
The Controversy Over Hormone Replacement Therapy
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Author :
language : en
Publisher: Am Cncl on Science, Health
Release Date :
The Controversy Over Hormone Replacement Therapy written by and has been published by Am Cncl on Science, Health this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Hormones And Breast Cancer In Post Menopausal Women
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Author : Sandra Z. Haslam
language : en
Publisher: IOS Press
Release Date : 2006
Hormones And Breast Cancer In Post Menopausal Women written by Sandra Z. Haslam and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Breast categories.
Focuses on the challenges of determining the mechanistic basis for the role of hormones in the etiology of postmenopausal breast cancer. This book intends to bring attention to the advancements and challenges facing effective prevention and treatment of this disease.
Risk Factors For Breast Cancer
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Author :
language : en
Publisher: Am Cncl on Science, Health
Release Date :
Risk Factors For Breast Cancer written by and has been published by Am Cncl on Science, Health this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Estrogen Prevention For Breast Cancer
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Author : Zsuzsanna Suba
language : en
Publisher:
Release Date : 2014-05-14
Estrogen Prevention For Breast Cancer written by Zsuzsanna Suba and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Medical categories.
From the early 80s of the past century, clinical and epidemiological studies have increasingly pointed to an elevated breast, endometrial and ovarian cancer risk from high circulating estrogen levels. Estrogen deficiency as a cancer risk factor emerged first in 2007 in a study on Hungarian oral cancer cases based on the gender and age- related differences in tumor prevalence. Critical reevaluation of the contradictory results of hormone replacement therapy yielded a complete conversion that estrogen deficiency may confer cancer initiation. This book examines the deleterious interactions between estrogen deficiency and further hormonal disorders which illuminate the apparently controversial associations of obesity, light exposure and alcohol intake with breast cancer risk.
Women S Health In Menopause
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Author : P.G. Crosignani
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Women S Health In Menopause written by P.G. Crosignani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Few topics in women's medicine today are as fraught with confusion and controversy as the question of appropriate treatment for menopausal symptoms and the prevention of negative long term health outcomes common to post-menopausal women. Cardiovascular disease (CVD), osteoporosis, and cancer -- the most common causes of death, disability and impaired quality of life for women -- can potentially be prevented or forestalled by dietary, behavioral, and drug interventions. A better understanding of the natural history of the menopause is critical to providing better care. If women and their physicians have a better understanding of predictors of risk, they could make more informed decisions about interventions related to menopausal symptoms, CVD, osteoporosis and gynecologic and breast cancer. Few other recently introduced medical interventions have as great a potential of affecting morbidity and mortality as does hormone replacement therapy (HRT). HRT has produced effect on health risk: some are reduced, some are raised, and some uncertain, and these data are interpreted differently by various scientific, medical and consumer groups.