Host Response To Biomaterials
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Host Response To Biomaterials
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Author : Stephen F. Badylak
language : en
Publisher: Academic Press
Release Date : 2015-05-08
Host Response To Biomaterials written by Stephen F. Badylak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-08 with Medical categories.
Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. - Explains the various categories of biomaterials and their significance for clinical applications - Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine - Includes regulations regarding combination devices
Immunomodulatory Biomaterials
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Author : Stephen F. Badylak
language : en
Publisher: Woodhead Publishing
Release Date : 2021-07-30
Immunomodulatory Biomaterials written by Stephen F. Badylak and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-30 with Technology & Engineering categories.
Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an "inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. - Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response - Provides a single reference for understanding and utilizing the host response in biomaterials design - An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area
Biomaterials In Regenerative Medicine And The Immune System
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Author : Laura Santambrogio
language : en
Publisher: Springer
Release Date : 2015-09-04
Biomaterials In Regenerative Medicine And The Immune System written by Laura Santambrogio and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-04 with Technology & Engineering categories.
The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components. As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.
Handbook Of Biomaterial Properties
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Author : William Murphy
language : en
Publisher: Springer
Release Date : 2016-06-11
Handbook Of Biomaterial Properties written by William Murphy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-11 with Technology & Engineering categories.
This book provides tabular and text data relating to normal and diseased tissue materials and materials used in medical devices. Comprehensive and practical for students, researchers, engineers, and practicing physicians who use implants, this book considers the materials aspects of both implantable materials and natural tissues and fluids. Examples of materials and topics covered include titanium, elastomers, degradable biomaterials, composites, scaffold materials for tissue engineering, dental implants, sterilization effects on material properties, metallic alloys, and much more. Each chapter author considers the intrinsic and interactive properties of biomaterials, as well as their appropriate applications and historical contexts. Now in an updated second edition, this book also contains two new chapters on the cornea and on vocal folds, as well as updated insights, data, and citations for several chapters.
Biomaterials Science
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Author : William R Wagner
language : en
Publisher: Academic Press
Release Date : 2020-05-23
Biomaterials Science written by William R Wagner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-23 with Technology & Engineering categories.
The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials' community. - The most comprehensive coverage of principles and applications of all classes of biomaterials - Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. - Online chapter exercises available for most chapters
Wound Closure Biomaterials And Devices
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Author : Chih-Chang Chu
language : en
Publisher: CRC Press
Release Date : 1996-12-20
Wound Closure Biomaterials And Devices written by Chih-Chang Chu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-12-20 with Medical categories.
Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï Sutures and other wound closure devices, including absorbable sutures and their biodegradation properties ï The chemistry, physics, mechanics, biology, and biomaterials science of suture materials ï Tissue adhesive, ligating clips, and staplers ï The biomechanics and pathology of wound healing ï Future trends and new emerging materials in the treatment of wound closure
Handbook Of Biomaterials Biocompatibility
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Author : Masoud Mozafari
language : en
Publisher: Woodhead Publishing
Release Date : 2020-06-16
Handbook Of Biomaterials Biocompatibility written by Masoud Mozafari and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-16 with Technology & Engineering categories.
Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology.
The Immune Response To Implanted Materials And Devices
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Author : Bruna Corradetti
language : en
Publisher: Springer
Release Date : 2016-11-30
The Immune Response To Implanted Materials And Devices written by Bruna Corradetti and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-30 with Technology & Engineering categories.
This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.
An Introduction To Biomaterials
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Author : Jeffrey O. Hollinger
language : en
Publisher: CRC Press
Release Date : 2005-12-21
An Introduction To Biomaterials written by Jeffrey O. Hollinger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-21 with Medical categories.
The complexity of biological systems and the need to design and develop biomedical therapies poses major challenges to professionals in the biomedical disciplines. An Introduction to Biomaterials emphasizes applications of biomaterials for patient care. Containing chapters prepared by leading authorities on key biomaterial types, this book underscores the process of biomaterial design, development directed toward clinical application, and testing that leads to therapies for clinical targets. The authors provide a lucid perspective on the standards available and the logic behind the standards in which biomaterials address clinical needs. This volume includes chapters on consensus standards and regulatory approaches to testing paradigms, followed by an analysis of specific classes of biomaterials. The book closes with sections on clinical topics that integrate materials sciences and patient applications.
Smart Ways Of Biomaterial Designing Synthesis And Characterization
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Author : Arvind K. Singh Chandel
language : en
Publisher: CRC Press
Release Date : 2025-03-07
Smart Ways Of Biomaterial Designing Synthesis And Characterization written by Arvind K. Singh Chandel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-07 with Science categories.
This book explores the design, synthesis, and characterization of natural and synthetic polymeric biomaterials for diverse biomedical applications, including drug delivery, tissue engineering, and antimicrobial coatings. It highlights advances in polymer chemistry, offering insights into the modification of polymers’ properties to meet biomedical challenges. The book provides detailed strategies for material design and characterization, addressing practical issues faced by researchers. It also covers crucial aspects such as materials-tissue interaction, sterilization prior to in vivo use, and the characterization of biomaterials for development. Serving as a comprehensive guide for students, researchers, and professionals in the biomedical field, this book aims to bridge the gap between laboratory research and clinical applications.