Hpv And Head And Neck Cancer
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Hpv And Head And Neck Cancer An Issue Of Otolaryngologic Clinics E Book
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Author : Sara I Pai
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-07-29
Hpv And Head And Neck Cancer An Issue Of Otolaryngologic Clinics E Book written by Sara I Pai and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-29 with Medical categories.
HPV is a growing epidemic in head and neck cancer and specialists working with these diseases are provided information on shifting trends in HPV in head and neck cancers along with challenges and controversies in treating this disease. With this virus related cancer, there is a different approach to managing this patient population. Novel therapeutic treatments are actively being developed for this type of head and neck cancer. Topics include: Epidemioloygy of HPV-head and neck cancer; Clinical detection of HPV; Clinical evaluation and disease patterns of HPV-related head and neck cancers; Impact of HPV-related head and neck cancer in clinical trials; Molecular biology of HPV and head and neck cancer and targeted therapies; Transoral robotic surgery: new surgical techniques for oropharyngeal cancers; Economic impact of HPV-related cancers; Rehabilitation needs of oropharyngeal cancer patients; Psychosocial care needs of HPV-head and neck cancer patients; and a Multi-disciplinary approach to head and neck cancers.
Hpv And Head And Neck Cancers
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Author : Carole Fakhry
language : en
Publisher: Springer
Release Date : 2015-07-11
Hpv And Head And Neck Cancers written by Carole Fakhry and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-11 with Medical categories.
This book serves a snapshot of the current knowledge base in field. As human papillomavirus (HPV) causes a rising number of oropharyngeal cancers, understanding the biological, clinical and social implications of this infection has become increasingly important for head and neck practitioners. This book reflects the multidisciplinary nature of the scientific and clinical questions involved in this disease. Experts in epidemiology, diagnosis and treatment of HPV-related oropharyngeal cancer present in-depth reviews which will help to improve the reader’s understanding of this topic. The authors provide insight for answers of common patient and provider questions about HPV infection and related disease, and highlight remaining questions to be answered in the coming years.
Hpv Infection In Head And Neck Cancer
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Author : Wojciech Golusiński
language : en
Publisher: Springer
Release Date : 2016-10-03
Hpv Infection In Head And Neck Cancer written by Wojciech Golusiński and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-03 with Medical categories.
This book is exceptional in presenting an interdisciplinary approach to the subject of human papillomavirus (HPV) infection in the context of head and neck cancer. Leading experts in the field discuss the epidemiology and molecular biology of HPV-positive head and neck squamous cell carcinoma, HPV testing, the nonsurgical and surgical treatment of HPV-positive tumors, predictive factors for outcome and quality of life, and ongoing trials on the effectiveness of vaccination in disease prevention. It also provides recommendations for testing, diagnosis treatment and vaccination. Otolaryngologists, head and neck surgeons, medical oncologists, radiation oncologists, molecular biologists and pathologists will find this book a valuable resource.
Advances In The Involvement Of Human Papilloma Virus In Head And Neck Squamous Cell Carcinoma
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Author : Jerome R. Lechien
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-25
Advances In The Involvement Of Human Papilloma Virus In Head And Neck Squamous Cell Carcinoma written by Jerome R. Lechien and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-25 with Medical categories.
Head And Neck Cancer
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Author : Eric M. Genden
language : en
Publisher: Thieme
Release Date : 2019-09-13
Head And Neck Cancer written by Eric M. Genden and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-13 with Medical categories.
Thieme congratulates Dr. Eric M. Genden on being chosen by New York magazine for its prestigious 'Best Doctors 2018' list! Head and Neck Cancer: Management and Reconstruction, 2nd Edition by Eric M. Genden masterfully blends two lauded Thieme books, Reconstruction of the Head and Neck, focusing on defect repair, and Head and Neck Cancer, a multidisciplinary, evidence-based approach to treatment. A significant increase in the incidence of oropharyngeal cancer in the U.S. and other countries, especially among men, is attributed to high-risk subtypes of the human papillomavirus (HPV). HPV associated tonsillar cancer and base of tongue cancer account for 90% of all oropharyngeal squamous cell carcinoma. Internationally renowned authors share the latest knowledge on HPV and other causes of head and neck cancers, from diagnosis to cutting-edge treatments. Thirty richly illustrated chapters feature open and endoscopic ablative techniques for treating a full spectrum of carcinomas and associated defects of the buccal, mandible and composite, laryngeal, hypopharyngeal, and parotid. The book encompasses the nuances of each pathology, step-by-step procedural guidance, clinical pearls, and the latest reconstructive techniques such as 3-D. For each disease, the authors discuss management concepts followed by principles of reconstruction and functional rehabilitation. Special topics include patient surveillance, monoclonal antibodies and immunotherapy, microvascular reconstruction, and minimizing wound complications. Key Features State-of-the-art management of carcinomas impacting the oral and nasal cavities, salivary glands, oropharynx, hypopharynx, larynx, thyroid, anterior skull base, skin, and more A chapter devoted to transoral robotic management of the oropharynx includes epidemiology, etiology, anatomy, staging, clinical presentation, diagnosis, work-up, and case studies More than 300 high-quality illustrations and photos elucidate complex anatomy and surgical approaches Concise videos posted online in the Thieme MediaCenter provide insightful hands-on surgical guidance This is the definitive, one-stop resource on the use of ablative and reconstructive approaches for head and neck cancers. Residents, fellows, and veteran practitioners in otolaryngology—head and neck surgery, radiation oncology, and medical oncology will benefit from this comprehensive reference.
Human Papillomavirus Hpv Associated Oropharyngeal Cancer
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Author : Daniel L. Miller
language : en
Publisher: Springer
Release Date : 2015-08-01
Human Papillomavirus Hpv Associated Oropharyngeal Cancer written by Daniel L. Miller and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-01 with Medical categories.
Head and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways. Due to public health efforts encouraging smoking cessation, the overall incidence of HNSCC has decreased in recent years in many countries. In contrast, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased significantly, and this subtype of HNSCC is commonly associated with human papillomavirus (HPV) infection. Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity. This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches. Chapters are contributed by authoritative leaders in the fields of research and clinical care. Initial chapters address epidemiology, behavioral correlates of HPV infection, and racial disparities in oropharyngeal cancer. This is followed by chapters detailing HPV virology with focus on viral transformation, viral replication, and host response to viral infection. The molecular biology of HPV-associated OPSCC is investigated in chapters detailing alterations in signaling networks and unique mutational profiles of human tumors. Clinical presentation, surgical perspectives, and treatment paradigms specific to HPV-associated OPSCC conclude the volume. This comprehensive volume provides an up-to-date overview of both scientific discovery and clinical management of this emerging public health problem.
Molecular Determinants Of Head And Neck Cancer
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Author : Barbara Burtness
language : en
Publisher: Springer
Release Date : 2018-08-03
Molecular Determinants Of Head And Neck Cancer written by Barbara Burtness and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-03 with Medical categories.
Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies. It is estimated that approximately 50,000 patients develop head and neck cancer annually in the United States, of whom approximately 50% succumb to this cancer. For most cases of SCCHN, treatment is multimodal, often combining surgery or irradiation with chemotherapy; even successfully treated patients frequently experience durable and severe side effects. Improving cure rates and reducing chronic morbidity are urgent clinical needs for head and neck cancer. However, in contrast to cancer types such as breast or prostate that have been much studied and have well-defined biology, until recently, relatively few researchers investigated the molecular basis of HNC, making it difficult to design targeted treatments with better efficacy and less debilitating side effects. This volume will provide an overview of the factors contributing to disease pathogenesis, including the recognition of discrete molecular subtypes with distinct etiology, prognosis, and treatment response. This volume will familiarize the reader with the critical signaling pathways and oncogenic drivers for HNC. It will outline the differences between HPV-positive and HPV-negative disease, and how these differences affect treatment choice and outcome. The book will emphasize developments in the past five years, including the growing understanding of the genomic and epigenomic features of the disease based on analysis of next generation sequencing (NGS) data, and timely topics such as the analysis of HNC stem cell populations, non-coding mRNAs, and inflammatory response. It will address exciting new therapeutic approaches such as the use of immunotherapies to treat HNC patients. Overall, the book will provide the reader with current understanding of the biology and treatment of the disease, and describe timely questions that will guide future research aimed at controlling and curing this disease.
Human Papillomavirus And Head And Neck Cancer
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Author : Heather Walline
language : en
Publisher:
Release Date : 2023
Human Papillomavirus And Head And Neck Cancer written by Heather Walline and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with categories.
In the study of head and neck squamous cell carcinoma (HNSCC), we know that virally induced malignancies behave differently than those generated through other carcinogenic mechanisms. This paradigm extends into differences in tumor growth, treatment response and resistance, as well as invasion and metastasis. The inability to correctly diagnose and appropriately treat HNSCC at early stages has contributed to reduced survival for HNSCC patients, particularly those with HPV-negative disease. The examination of the molecular differences between HPV-positive and HPV-negative HNSCC will provide support for early diagnostic markers and guide appropriate treatment selection to improve patient care and survival.This Special Issue highlights current research efforts to understand the evolving contribution of human papillomavirus in HNSCC.
Critical Issues In Head And Neck Oncology
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Author : Jan B. Vermorken
language : en
Publisher: Springer Nature
Release Date : 2023-03-27
Critical Issues In Head And Neck Oncology written by Jan B. Vermorken and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-27 with Medical categories.
This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.
Head And Neck Cancer Hallmarks Of The Inflammation Ecosystem
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Author : Norhafiza Mat Lazim
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-03-31
Head And Neck Cancer Hallmarks Of The Inflammation Ecosystem written by Norhafiza Mat Lazim and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-31 with Medical categories.
This reference comprehensively covers the clinical aspects of head and neck neoplasms while also highlighting the relationship that exists between inflammation and these cancers. This relationship is critical as it dictates the risks, assessment, treatment, and prognosis of head and neck cancer patients. The book starts with an introduction to the inflammation ecosystem in head and neck malignancy, followed by detailed discussions on the types of head and neck malignancy and their histological classification. The book then provides information about specialized topics relevant to the specialty of head and neck oncology. Key Features: - Comprehensive coverage of head and neck cancers with topic-based chapters - Introductory text explaining the basics of inflammation - Detailed information on the relationship between inflammation and head and neck neoplasms - Information about the classification of head and neck cancers - Methods for diagnosis and treatment - Special topics such as complications caused by HPV infections, chemoradiation, immune-targeted therapy, and inflammatory biomarkers - References for further reading The combination of basic and advanced topics makes this book an informative reference for medical students and professionals at all levels. Residents specializing in otolaryngology, oncology, and surgery as well as researchers studying inflammation will also gain an understanding of the subject in relation to oncogenesis.