Human Circulating Tumor Markers
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Human Circulating Tumor Markers
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Author : James T. Wu
language : en
Publisher: American Society of Clinical Pathologists Press
Release Date : 1997
Human Circulating Tumor Markers written by James T. Wu and has been published by American Society of Clinical Pathologists Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Tumor markers categories.
Circulating Tumor Markers Of The New Millennium
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Author : James T. Wu
language : en
Publisher: Amer. Assoc. for Clinical Chemistry
Release Date : 2002
Circulating Tumor Markers Of The New Millennium written by James T. Wu and has been published by Amer. Assoc. for Clinical Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The hope is that by measuring soluble, circulating markers, targets for cancer therapy can be identified with non-invasive procedures. To help attain that goal, Wu (pathology, U. of Utah-Salt Lake City) identifies and describes any circulating tumor markers he thinks might help. Annotation copyrighted by Book News, Inc., Portland, OR
Circulating Tumor Cells
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Author : Richard J. Cote
language : en
Publisher: Springer
Release Date : 2016-02-03
Circulating Tumor Cells written by Richard J. Cote and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-03 with Medical categories.
This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers. CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive “liquid biopsy” procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development. In recent years there has been rapid growth and worldwide developments on CTCs, which span both the basic sciences and biomedical engineering fields.
Circulating Tumor Cells
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Author : Catherine Alix-Panabieres
language : en
Publisher: MDPI
Release Date : 2020-04-03
Circulating Tumor Cells written by Catherine Alix-Panabieres and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-03 with Science categories.
The analysis of circulating tumor cells (CTCs) as a real-time liquid biopsy approach can be used to obtain new insights into metastasis biology, and as companion diagnostics to improve the stratification of therapies and to obtain insights into the therapy-induced selection of cancer cells. In this book, we will cover all the different facets of CTCs to assemble a huge corpus of knowledge on cancer dissemination: technologies for their enrichment, detection, and characterization; their analysis at the single-cell level; their journey as CTC microemboli; their clinical relevance; their biology with the epithelial-to-mesenchymal transition (EMT); their stem-cell properties; their potential to initiate metastasis at distant sites; their ex vivo expansion; and their escape from the immune system.
Human Cancer Markers
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Author : Stewart Sell
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Human Cancer Markers written by Stewart Sell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The ability to diagnose cancer by simple measurement of a serum or tissue' 'marker" has been a goal of medical science for many years. There is ample evidence that tumor cells are different from normal cells and pro duce substances that can be detected by currently available immuno chemical or biochemical methods. These "cancer markers" may be se creted proteins, enzymes, hormones, fetal serum components, monoclonal immunoglobulins, cell surface components, or cytoplasmic constituents. The purpose of this book is to present the current status of our knowledge of such cancer markers. The first tumor marker identified by laboratory means was Bence Jones protein. In a series of lectures delivered to the Royal College of Phy sicians in London in 1846, Dr. H. Bence Jones described studies on a urine sample sent to him with the following note: "Dear Dr. Jones-The tube contains urine of very high specific gravity. When boiled it becomes slightly opaque . . . . etc. " Dr. Jones found that heating of the urine after addition of nitric acid resulted in formation of a heavy precipitate; acid ad dition may have been required to bring the urine to pH 4-6 at which Bence Jones proteins are more likely to precipitate when heated. This urinary pre cipitate was associated with a bone disease termed "mollities ossium. " [H. Bence Jones, Papers on Chemical Pathology, Lecture III. Lancet 2, 269-274 (1847)].
Serological Cancer Markers
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Author : Stewart Sell
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Serological Cancer Markers written by Stewart Sell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The purpose of this book-the fourth volume of a series on Can cer Markers-is intended to provide an updated "status report" on today's use of cancer markers in the diagnosis and monitoring of can cer, with an emphasis on cancer markers detected in the serum. It has been 7 years since the publication of the last volume in this series. The 1980, 1982, and 1985 volumes covered the development of cancer markers, not only in their roles of unraveling the basic biology of can cer, but also as increasingly important players in the management of patients with cancer. During the last 7 years we have seen the applica tion of a number of markers identified by monoclonal antibodies, as well as the beginnings of the use of genetic markers defined by mo lecular probes. Measurements of oncogenes in tissues or cells prom ise many applications for the future, but as yet, these genes have not shown to be useful as serum markers of cancer. The commercial interest in serum markers for cancer, particu larly for the diagnosis and monitoring of tumor patients, is indicated in Chapter 24 by Owen, where the total worldwide market for cancer markers is projected to increase from $148 million in 1988 to $232 million in 1993. The degree of research interest in cancer markers is reflected in the fact that in 1988 a separate category for tumor mark ers was added to Index Medicus.
Tumor Markers
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Author : Eleftherios P. Diamandis
language : en
Publisher: Amer. Assoc. for Clinical Chemistry
Release Date : 2002
Tumor Markers written by Eleftherios P. Diamandis and has been published by Amer. Assoc. for Clinical Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
Human Tumor Markers Biological Basis And Clinical Relevance
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Author : Herbert E. Nieburgs
language : en
Publisher:
Release Date : 1983
Human Tumor Markers Biological Basis And Clinical Relevance written by Herbert E. Nieburgs and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Cancer categories.
Liquid Biopsy
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Author : Ilze Strumfa
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-07-10
Liquid Biopsy written by Ilze Strumfa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-10 with Medical categories.
Reliable diagnosis is the cornerstone, starting point, and prerequisite of successful treatment. Therefore, development of innovative diagnostic technologies represents a hot topic in medical research. Liquid biopsy is a novel, minimally invasive laboratory evaluation concept for diagnostic, prognostic, and predictive testing, as well as dynamic monitoring of treatment or disease course. To achieve these goals, a multitude of specific, targeted tests can be performed to detect free nucleic acids, exosomes, microRNAs, tumor-educated platelets, and whole cells of tumor or fetal origin in different biological fluids, including blood, urine, cerebrospinal fluid, and others. Although tissue biopsy has long been considered the gold standard of diagnostics, especially regarding malignant tumors, liquid biopsy has the advantages of a non-invasive approach and thus low risk of complications. It is technically feasible even in serious general status or if tumors or metastases are not easily accessible using conventional tissue biopsy. The testing is fast, exact, and can be repeated to ensure real-time follow-up. In contrast to classic tumor markers, liquid biopsy is distinguished by high specificity at genomic, proteomic, and cellular levels. It is expected to equal and exceed the diagnostic value of tissue biopsy. The field of liquid biopsies is developing rapidly regarding the selection of targets, technological improvements, and quality assessment. This book, written by a global team of recognized scientists, comprises state-of-the-art reviews on the current knowledge and advances in the technologies and software for liquid biopsy. Examples of practical application of liquid biopsy to evaluate thyroid cancer, multiple myeloma, etc. are discussed as well. The book is intended to serve as a reference for scientists and clinicians interested in the development and practical implementation of liquid biopsy.
Human Tumor Markers
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Author : Stanford W. Ting
language : en
Publisher:
Release Date : 1989
Human Tumor Markers written by Stanford W. Ting and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medical categories.
