Human Organs On A Chip Technology
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Human Organs On A Chip Technology
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Author : P.V. Mohanan
language : en
Publisher: Elsevier
Release Date : 2024-06-18
Human Organs On A Chip Technology written by P.V. Mohanan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-18 with Science categories.
Human Organs-on-a-Chip Technology focuses on the technology advancement from "organ-on-a-chip to "multi organs-on-a-chip to the newest stage of "human organs-on-a-chip. Chapters investigate the design, simulation studies, device development and application of microfluidic systems. They also offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research. - Explores organs-on-a-chip technology, from the basics, to advanced developments and existing challenges and recent research trends and applications - Reviews every aspect of microfluidic devices, including biological evaluation and targeted delivery - Includes the latest information on regulatory updates
Human Organs On A Chip
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Author : Javier Ramón-Azcón
language : en
Publisher: Elsevier
Release Date : 2023-11-15
Human Organs On A Chip written by Javier Ramón-Azcón and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-15 with Science categories.
Human Organs-on-Chip: Novel Organ-on-a-Chip Techniques in Medicine paves the way for novel approaches that push forward in-vitro and in-vivo studies and fills a gap between laboratory and clinical use. These experienced authors share the knowledge they've developed with over a decade of experience and research with organ-on-chips and multi-organ-on-chips. This book collects all of the developments in the field and sheds new light on possibilities to develop human on-chip measurement methods with the utilization of currently available measurement techniques including both invasive and non-invasive tests. Human Organs-on-Chip: Novel Organ-on-a-Chip Techniques in Medicine serves as a starting point for young researchers who are beginning their scientific journeys. - Provides an overview of the progress suborgan-on-chips development has made in recent years - Introduces the fundamentals needed to understand lab-on-chip ideas with references and in-depth explanations - Presents commercial achievements obtained and future perspectives
Stem Cells
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Author : Christine L. Mummery
language : en
Publisher: Academic Press
Release Date : 2014-05-23
Stem Cells written by Christine L. Mummery and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-23 with Science categories.
The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. - Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy - Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice - Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice
Biochip Technology
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Author : Jing Cheng
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Biochip Technology written by Jing Cheng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Science categories.
Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.
Microfluidics And Lab On A Chip
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Author : Andreas Manz
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-09-24
Microfluidics And Lab On A Chip written by Andreas Manz and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-24 with Science categories.
Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.
Biofabrication
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Author : Ritu Raman
language : en
Publisher: MIT Press
Release Date : 2021-09-14
Biofabrication written by Ritu Raman and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-14 with Technology & Engineering categories.
How engineered materials and machines powered by living biological cells can tackle technological challenges in medicine, agriculture, and global security. You are a biological machine whose movement is powered by skeletal muscle, just as a car is a machine whose movement is powered by an engine. If you can be built from the bottom up with biological materials, other machines can be as well. This is the conceptual starting point for biofabrication, the act of building with living cells--building with biology in the same way we build with synthetic materials. In this volume in the MIT Press Essential Knowledge series, Ritu Raman offers an accessible introduction to biofabrication, arguing that it can address some of our greatest technological challenges. After presenting the background information needed to understand the emergence and evolution of biofabrication and describing the fundamental technology that enables building with biology, Raman takes deep dives into four biofabrication applications that have the potential to affect our daily lives: tissue engineering, organs-on-a-chip, lab-grown meat and leather, and biohybrid machines. Organs-on-a-chip (devices composed of miniature model tissues), for example, could be used to test new medicine and therapies, and lab-grown meat could alleviate environmental damage done by animal farming. She shows that biological materials have abilities synthetic materials do not, including the ability to adapt dynamically to their environments. Exploring the principles of biofabrication, Raman tells us, should help us appreciate the beauty, adaptiveness, and persistence of the biological machinery that drives our bodies and our world.
Principles Of Human Organs On Chips
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Author : Masoud Mozafari
language : en
Publisher: Woodhead Publishing
Release Date : 2023-01-17
Principles Of Human Organs On Chips written by Masoud Mozafari and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-17 with Technology & Engineering categories.
Principles of Human Organs-on-Chips covers all aspects of microfluidic organ-on-a-chip systems, from fabrication to application and commercialization. Organ-on-a-chip models are created to mimic the structural, microenvironmental and physiological functions of human organs, providing the potential to bypass some cell and animal testing methods. This is a useful platform with widespread applications, frequently in drug screening and pathological studies. This book offers a comprehensive and authoritative reference on microfluidic organs-on-chips, spanning all key aspects from fabrication methods, cell culture systems and cell-based analysis, to dedicated chapters on specific tissue types and their associated organ-on-a-chip models, as well as their use as disease models, drug screening platforms and more. Principles of Human Organs-on-Chips helps materials scientists and biomedical engineers to better understand the specific requirements and challenges in the design and fabrication of organ-on-a-chip devices. This book also bridges the knowledge gap between medical device design and subsequent clinical applications, allowing medical professionals to easily learn about related engineering concepts and techniques. - Describes various microfluidic systems and fabrication methods - Covers models and applications for a broad range of tissue types, including liver, eye, immune, gut, and more - Offers an interdisciplinary approach, combining engineering techniques and clinical applications of organs-on-chips
Biofabrication
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Author : Gulden Camci-Unal
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-03-18
Biofabrication written by Gulden Camci-Unal and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-18 with Medical categories.
Microscale hydrogels are potentially useful materials for controlling cellular behavior to mimic native microenvironments for tissue engineering applications. In this chapter, various fabrication techniques to generate microscale hydrogels and their applications in tissue engineering have been outlined. In addition, we provide examples of microscale hydrogels with different physical and chemical properties for generation of tissue constructs. Finally, we discuss potential future directions in fabrication of hydrogels to address challenges in tissue engineering. It is expected that these techniques will enable engineering of three-dimensional (3D) structures with controlled features for the formation of functional tissues and organs.
Gum Arabic And Breast Cancer Biology
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Author : Ahmed A. M. Elnour
language : en
Publisher: Springer Nature
Release Date : 2025-02-10
Gum Arabic And Breast Cancer Biology written by Ahmed A. M. Elnour and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-10 with Medical categories.
This book delves into the intersection of gum arabic, a natural product derived from Acacia gums (AGs) including Acacia sengal, Acacia seyal and Acacia polyacantha gum, and breast cancer (BC)biology from a biotechnology perspective. It explores the history, extraction, characterization, and biological applications of secondary metabolites (SMs) extracted from AGs. The chapters cover topics such as the physicochemical properties of AGs, advanced extraction methods for secondary metabolites, and their diverse biological applications, including antimicrobial, anti-inflammatory, and anticancer properties. The book also examines state-of-the-art breast cancer research, its impact on sustainable development goals, and the potential applications of AG's secondary metabolites in BC cell lines. Additionally, it discusses the opportunity to transfer cancer-on-a-chip technology to Islamic Development Bank member countries (IsDB-MCs) and explores the application of breast-on-a-chip technology using AGs-secondary metabolites (SME). This comprehensive book combines the fields of biotechnology, breast cancer biology, and natural product research, offering a unique perspective on the potential role of gum Arabic or AGs secondary metabolites in breast cancer research and treatment. Researchers in the fields of biotechnology, oncology, and natural product chemistry find this book invaluable. Whether you are exploring new frontiers in cancer treatment or a practitioner seeking novel therapeutic approaches, this book provides critical insights into innovative strategies for combating breast cancer. Additionally, it serves as an essential resource for policymakers interested in integrating development goals with healthcare advancements.
Organ On A Chip
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Author : Julia Hoeng
language : en
Publisher: Academic Press
Release Date : 2019-11-09
Organ On A Chip written by Julia Hoeng and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-09 with Technology & Engineering categories.
Organ-on-a-Chip: Engineered Microenvironments for Safety and Efficacy Testing contains chapters from world-leading researchers in the field of organ on a chip development and applications, with perspectives from life sciences, medicine, physiology and engineering. The book contains an overview of the field, with sections covering the major organ systems and currently available technologies, platforms and methods. As readers may also be interested in creating biochips, materials and engineering best practice, these topics are also described. Users will learn about the limitations of 2D in-vitro models and the available 3D in-vitro models (what benefits they offer and some examples). Finally, the MOC section shows how the organ on a chip technology can be adapted to improve the physiology of in-vitro models. - Includes case studies of other organs on a chip that have been developed and successfully used - Provides insights into functional microphysiological organ on a chip platforms for toxicity and efficacy testing, along with opportunities for translational medicine - Presented fields (PK/PD, physiology, medicine, safety) are given a definition followed by the challenges and potential of organs on a chip