Human Pathogenic Microbes
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Human Pathogenic Microbes
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Author : Manzoor Ahmad Mir
language : en
Publisher: Academic Press
Release Date : 2022-03-16
Human Pathogenic Microbes written by Manzoor Ahmad Mir and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-16 with Science categories.
Considering the global emerging human pathogenic microbial diseases and trends, Human Pathogenic Microbes is framed to provide deep insights into the epidemic and emerging bacterial and fungal infections and diseases in humans. It presents novel, up-to-date, and cutting-edge knowledge regarding various human pathogenic microbes, their associated drug resistance mechanisms, and different diseases caused by them. Human Pathogenic Microbes reflects the current research and development on the evolution of bacterial and fungal drug resistance: different bacterial and fungal antimicrobial drug resistance mechanisms along with their biological and molecular aspects. In a nutshell, Human Pathogenic Microbes describes a various bacterial and fungal diseases caused by different human pathogenic microbes employing different drug resistance mechanisms and processes. It also highlights the novel emerging approaches (Immunological and combinatorial) that will aid to fight against such bacterial and fungal pathogens. Provides a brief but thorough and recent knowledge of various human pathogenic microbes, their associated drug resistance mechanisms, and different diseases caused by them Describes the different aspects of fungal, bacterial and antimicrobial resistance Addresses novel antimicrobial agents and approaches
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Proteomics Of Microbial Human Pathogens
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Author :
language : en
Publisher:
Release Date : 2017
Proteomics Of Microbial Human Pathogens written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
According to the World Health Organization (WHO), in 2012 infectious diseases and related conditions account for more than 70% of premature deaths across 22 African countries and estimated 450 000 people worldwide developed multi-drug resistant tuberculosis. This alarming situation, of great public health concern, calls for the urgent development of novel and efficient responding strategies. The employment of important research platforms, such as genomics and proteomics, has contributed significant insight into the mechanisms underlying microbial infection and microbe-host interaction. In this Frontiers Research Topic, we aim to produce a timely and pertinent discussion regarding the current status of "Proteomics of microbial Human pathogens" and the role of proteomics in combating the challenges posed by microbial infection and indeed acquired anti-microbial resistance. As the field of proteomics progressed from 2-DE gel based approaches to modern LC-MS/MS based workflows, remarkable advances have been reported in terms of data quantity and quality. Given the immediate and enormous advantages that high resolution and accurate mass spectrometers have brought to the field, proteomics has now evolved into a robust platform capable of generating large amounts of comprehensive data comparable to that reported previously in genomics studies. For example, detection of the complete yeast proteome has been reported and other small proteomes, such as those of bacteria, are within reach. Mass spectrometry-based proteomics has become an essential tool for biologists and biochemists, and is now considered by many as an essential component of modern structural biology. Additionally, the introduction of high-resolution mass spectrometers has driven the development of various different strategies aimed at accurate quantification of absolute and relative amount of protein(s) of interest. Emerging targeted mass spectrometry methodologies such as; Selected Reaction Monitoring (SRM), Parallel Reaction Monitoring (PRM) and SWATH, are perhaps the latest breakthrough within the proteomics community. Indeed, through a label free approach, targeted mass spectrometry offers an unequalled capability to characterize and quantify a specific set of proteins reproducibility, in any biological sample. Usefully, Aebersold and colleagues have recently generated and validated a number of assays to quantify 97% of the 4,012 annotated Mycobacterium tuberculosis (Mtb) proteins by SRM. As such, the Mtb Proteome library represents a valuable experimental resource that will undoubtedly bring new insight to the complex life cycle of Mtb. Finally, as reviewed recently in Frontiers Research Topic, mass spectrometry-based proteomics has had a tremendous impact on our current understanding of post translational modification (PTM) in bacteria including the key role of PTMs during interaction of pathogenic bacteria and host interactions. We believe that our understanding of microbial Human pathogens has benefited enormously from both 2-DE gel and modern LC-MS/MS based proteomics. It is our wish to produce an integrated discussion surrounding this topic to highlight the existing synergy between these research fields. We envisage this Research Topic as a window to expert opinions and perspectives on the realistic practicalities of proteomics as an important tool to address healthcare problems caused by microbial pathogens.
Proteomics Of Microbial Human Pathogens
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Author : Nelson C. Soares
language : en
Publisher: Frontiers Media SA
Release Date : 2017-01-17
Proteomics Of Microbial Human Pathogens written by Nelson C. Soares and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-17 with Electronic book categories.
According to the World Health Organization (WHO), in 2012 infectious diseases and related conditions account for more than 70% of premature deaths across 22 African countries and estimated 450 000 people worldwide developed multi-drug resistant tuberculosis. This alarming situation, of great public health concern, calls for the urgent development of novel and efficient responding strategies. The employment of important research platforms, such as genomics and proteomics, has contributed significant insight into the mechanisms underlying microbial infection and microbe-host interaction. In this Frontiers Research Topic, we aim to produce a timely and pertinent discussion regarding the current status of “Proteomics of microbial Human pathogens” and the role of proteomics in combating the challenges posed by microbial infection and indeed acquired anti-microbial resistance. As the field of proteomics progressed from 2-DE gel based approaches to modern LC-MS/MS based workflows, remarkable advances have been reported in terms of data quantity and quality. Given the immediate and enormous advantages that high resolution and accurate mass spectrometers have brought to the field, proteomics has now evolved into a robust platform capable of generating large amounts of comprehensive data comparable to that reported previously in genomics studies. For example, detection of the complete yeast proteome has been reported and other small proteomes, such as those of bacteria, are within reach. Mass spectrometry-based proteomics has become an essential tool for biologists and biochemists, and is now considered by many as an essential component of modern structural biology. Additionally, the introduction of high-resolution mass spectrometers has driven the development of various different strategies aimed at accurate quantification of absolute and relative amount of protein(s) of interest. Emerging targeted mass spectrometry methodologies such as; Selected Reaction Monitoring (SRM), Parallel Reaction Monitoring (PRM) and SWATH, are perhaps the latest breakthrough within the proteomics community. Indeed, through a label free approach, targeted mass spectrometry offers an unequalled capability to characterize and quantify a specific set of proteins reproducibility, in any biological sample. Usefully, Aebersold and colleagues have recently generated and validated a number of assays to quantify 97% of the 4,012 annotated Mycobacterium tuberculosis (Mtb) proteins by SRM. As such, the Mtb Proteome library represents a valuable experimental resource that will undoubtedly bring new insight to the complex life cycle of Mtb. Finally, as reviewed recently in Frontiers Research Topic, mass spectrometry-based proteomics has had a tremendous impact on our current understanding of post translational modification (PTM) in bacteria including the key role of PTMs during interaction of pathogenic bacteria and host interactions. We believe that our understanding of microbial Human pathogens has benefited enormously from both 2-DE gel and modern LC-MS/MS based proteomics. It is our wish to produce an integrated discussion surrounding this topic to highlight the existing synergy between these research fields. We envisage this Research Topic as a window to expert opinions and perspectives on the realistic practicalities of proteomics as an important tool to address healthcare problems caused by microbial pathogens.
Human Microbiology
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Author : Simon Hardy
language : en
Publisher: CRC Press
Release Date : 2003-08-27
Human Microbiology written by Simon Hardy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-27 with Science categories.
The widespread presence and activity of micro-organisms makes it impossible to study life sciences without some understanding of microorganisms. Human Microbiology provides a concise review of the biology of the three important groups of micro-organisms that infect humans: bacteria, viruses and fungi. Divided into two parts, it summarises the key features that characterise the physiology of microorganisms e.g. structure and function, growth and division, microbial death and the principles of taxonomy, and examines the common themes that are found in micro-organisms that cause disease in man, the transmission, epidemiology and pathogenicity of microbial diseases. With the overwhelming volume of information published on individual species of bacteria, viruses and fungi, Human Microbiology emphasises the important concepts and themes that occur in the organisms that are pathogenic to humans. The conventional approach to studying medical microbiology tends to result in exhaustive lists of microbes arranged by genus and their associated diseases. To promote understanding of the principles of medical microbiology and avoid memory lessons, the important concepts are discussed with reference to key examples.
Microbial Pathogens And Human Diseases
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Author : N A Khan
language : en
Publisher: CRC Press
Release Date : 2008-01-05
Microbial Pathogens And Human Diseases written by N A Khan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-05 with Medical categories.
This book provides a concise but comprehensive description of human infectious diseases due to microbial pathogens, from a physicians and a microbiologists point of view, as well as providing an understanding of the use of microbial pathogens as biological weapons. It is indispensable for students, physicians, medical and nursing staff, and infecti
Plants As Alternative Hosts For Human And Animal Pathogens
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Author : Nicola J. Holden
language : en
Publisher: Frontiers Media SA
Release Date : 2015-07-02
Plants As Alternative Hosts For Human And Animal Pathogens written by Nicola J. Holden and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-02 with Botany categories.
Many of the most prevalent and devastating human and animal pathogens have part of their lifecycle out-with the animal host. These pathogens have a remarkably wide capacity to adapt to a range of quite different environments: physical, chemical and biological, which is part of the key to their success. Many of the well-known pathogens that are able to jump between hosts in different biological kingdoms are transmitted through the faecal-oral and direct transmission pathways, and as such have become important food-borne pathogens. Some high-profile examples include fresh produce-associated outbreaks of Escherichia coli O157:H7 and Salmonella enterica. Other pathogens may be transmitted via direct contact or aerosols are include important zoonotic pathogens. It is possible to make a broad division between those pathogens that are passively transmitted via vectors and need the animal host for replication (e.g. virus and parasites), and those that are able to actively interact with alternative hosts, where they can proliferate (e.g. the enteric bacteria). This research topic will focus on plants as alternative hosts for human pathogens, and the role of plants in their transmission back to humans. The area is particularly exciting because it opens up new aspects to the biology of some microbes already considered to be very well characterised. One aspect of cross-kingdom host colonisation is in the comparison between the hosts and how the microbes are able to use both common and specific adaptations for each situation. The area is still in relative infancy and there are far more questions than answers at present. We aim to address important questions underlying the interactions for both the microbe and plant host in this research topic.
What You Need To Know About Infectious Disease
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Author : Madeline Drexler
language : en
Publisher:
Release Date :
What You Need To Know About Infectious Disease written by Madeline Drexler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Pathogenicity And Drug Resistance Of Human Pathogens
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Author : Saif Hameed
language : en
Publisher: Springer Nature
Release Date : 2020-01-23
Pathogenicity And Drug Resistance Of Human Pathogens written by Saif Hameed and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-23 with Medical categories.
The book comprehensively discusses the mechanisms of pathogenesis and drug resistance; current diagnostics landscape of four key human pathogens; bacterial, fungal, protozoans and viral which are the causes of major infectious diseases. It also assesses the emerging technologies for the detection and quantification of these pathogens. Further, it discusses the novel opportunities to fight against these infectious diseases and to identify pertinent drug targets with novel methodologies. It also reviews the current and future insights into the control, elimination, and eradication of these infectious diseases. Importantly, the book discusses the epidemiological characteristics and various challenges in combating Ebola and Influenza diseases. Finally, the book highlights the growing role of nanotechnology and bioinformatics resources for combating the infectious diseases. In summary, the book provides the mechanistic insight of the pathogenicity, drug-resistance, therapeutic strategies and identification of the novel drug targets of Mycobacterium tuberculosis, Plasmodium, Candida, Hepatitis C and emerging viral infections.
Recent Discoveries In Human Serious Foodborne Pathogenic Bacteria Resurgence Pathogenesis And Control Strategies
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Author : Lanming Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-06
Recent Discoveries In Human Serious Foodborne Pathogenic Bacteria Resurgence Pathogenesis And Control Strategies written by Lanming Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with categories.
Food is the first necessity for humans to survive with huge amounts of food consumed daily worldwide. Globalization of food industry results in an increasingly complex food chain, making food safety a universal issue. Many millions of people in the world become sick while hundreds of thousand die annually due to consumption of contaminated food. Pathogenic bacteria contaminate food at any stages in the food chain, including production, processing, supplying, and storage. The most commonly known bacterial pathogens associated with human foodborne diseases worldwide are Salmonella enterica, Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, Cronobacter sakazakii, Vibrio cholerae, and Vibrio parahaemolyticus. This eBook includes publications on recent discoveries in genetic diversity, prevalence, resistance and novel transmission vectors; molecular mechanisms underlying the pathogenesis; and new compounds and treatment strategies for better control of the human foodborne pathogenic bacteria. The information in the articles supports the urgent need for improving food safety and public health, particularly in globalization background.
