Hyaluronic Acid
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Hyaluronic Acid
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Author : V. N. Khabarov
language : en
Publisher: John Wiley & Sons
Release Date : 2015-03-16
Hyaluronic Acid written by V. N. Khabarov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-16 with Science categories.
Hyaluronic acid is an essential part of connective, epithelial and neural tissues, and contributes to cell proliferation and migration. It is used as a stimulating agent for collagen synthesis and is a common ingredient in skin-care products, a multi-billion dollar industry, as it is believed to be a key factor in fighting the aging process. Hyaluronic Acid: Production, Properties, Application in Biology and Medicine consists of six chapters discussing the various issues of hyaluronic acid research. In Chapter 1, a historical analysis recounts the discovery and milestones of the research leading to the practical applications of hyaluronan. Chapter 2 is dedicated to biological role of the hyaluronic acid in nature, in particular in the human body. The chapter starts from the phylogenesis of hyaluronic acid, then describes hyaluronan functions in human ontogenesis and especially the role which hyaluronan plays in extracellular matrix of the different tissues. Chapter 3 describes the methods to manufacture and purify hyaluronic acid, including the analytical means for assessing quality of the finished product. Chapter 4 discusses the structure and rheological properties of hyaluronic acid considering effects on conformation and biological properties related to molecular weight. In Chapter 5, the physical and chemical methods for modifying the structure of hyaluronan are discussed including cross-linking using bi-functional reagents, solid-phase modification and effects of the combined action of high pressures and shift deformation. The final chapter focuses on the products derived from hyaluronic acid, including therapeutics composed of modified hyaluronan conjugated to vitamins, amino acids and oligo-peptides. The biological roles and medical applications of this polysaccharide have been extensively studied and this book provides a wealth of scientific data demonstrating the critical role of hyaluronic acid and its promise as a multifaceted bio-macromolecule. Approaching hyaluronic acid from multiple angles, this book links relationships between its biological functions, structure and physical–chemical properties. It will be an invaluable resource to researchers, both industrial and academic, involved in all aspects of hyaluronan-based technologies.
Studies In The Hyaluronidase Hyaluronic Acid System
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Author : Alice L. Mathis
language : en
Publisher:
Release Date : 1949
Studies In The Hyaluronidase Hyaluronic Acid System written by Alice L. Mathis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1949 with Hyaluronic acid categories.
Hyaluronic Acid For Biomedical And Pharmaceutical Applications
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Author : Maurice N Collins
language : en
Publisher: Smithers Rapra
Release Date : 2014-10-09
Hyaluronic Acid For Biomedical And Pharmaceutical Applications written by Maurice N Collins and has been published by Smithers Rapra this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-09 with Medical categories.
Hyaluronic acid (HA) is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterials science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials. Its properties, both physical and biochemical, in solution or hydrogel form, are extremely attractive for various technologies concerned with body repair. This book considers the materials science behind some of the important biomedical and therapeutic applications that are emerging for HA. Key characteristics such as its mechanical properties, biological function and degradation are discussed. The latest technologies in chemical modification and crosslinking strategies are analysed and emerging applications in soft and hard tissue repair are highlighted. The first objective of the book, which consists of a collection of chapters from leading researchers across the globe, is to highlight the role of HA based hydrogels as scaffolds in sustaining stem cells for transplantation and regrowth. The second objective is to detail the significant influence of HA derived materials in the latest advances in cancer therapy, general therapeutics and cosmetics. The third objective is to link the structure-property relationships of HA to medical function and application while reflecting on current clinical and market trends. The book will be of interest to those involved in HA research for medical device and therapeutic applications. Graduate and undergraduate students engaged in the fields of biomedical engineering, materials science, chemistry, medical science, pharmaceutical science and polymer science will find this book of particular interest.
Hyaluronic Acid
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Author : Riia Rautiola
language : en
Publisher:
Release Date : 2020-02-19
Hyaluronic Acid written by Riia Rautiola and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-19 with Science categories.
"Hyaluronic acid, or hyaluronan, is a water soluble, anionic extracellular matrix glycosaminoglycan polymer with variable molecular weight that determines its physiological role, rheological properties and applications. Since its discovery in the early 1930s, there has been an increased awareness concerning the biology of hyaluronic acid, its signaling pathways and its role in the biomedical and cosmeceutical industry. Being an endogenous molecule, hyaluronic acid is biocompatible, biodegradable, and has strong mucoadhesive, viscoelastic properties. The authors provide chemical modification approaches to hyaluronic acid, as well as address the magnitude of applications of hyaluronic acid-based targeted drug vectors and patents. The closing study discusses glycosaminoglycans, a specialized group of unbranched, anionic disaccharide polymers attached by a covalent linkage to the membrane proteins via sulphate groups in their sugar moieties"--
Effect Of X Irradiation On The Hyaluronidase Hyaluronic Acid System
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Author : Melvin D. Schoenberg
language : en
Publisher:
Release Date : 1950
Effect Of X Irradiation On The Hyaluronidase Hyaluronic Acid System written by Melvin D. Schoenberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1950 with Hyaluronic acid categories.
Studies In The Hyaluronidase Hyaluronic Acid System
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Author : Robert E. Brooks
language : en
Publisher:
Release Date : 1949
Studies In The Hyaluronidase Hyaluronic Acid System written by Robert E. Brooks and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1949 with Hyaluronic acid categories.
The Hyaluronic Acid Miracle
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Author : Chris D. Meletis
language : en
Publisher:
Release Date : 2010-09
The Hyaluronic Acid Miracle written by Chris D. Meletis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09 with Aging categories.
A complete guide to the world's most exciting anti-aging compound for flexible joints, vibrant skin and a healthy heart. Now, for the first time, the anti-aging secrets of hyaluronic acid are revealed by two of the leading experts. Learn how hyaluronic acid can: *Give anyone an instant facelift *Replace a Botox injection *Offer full, plump lips and skin *Thicken your hair *Improve your vision and eliminate floaters *Provide the cushioning fluid your joints need to move freely *Improve your heart and circulatory health
Chemistry And Biology Of Hyaluronan
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Author : Hari G. Garg
language : en
Publisher: Elsevier
Release Date : 2004-07-14
Chemistry And Biology Of Hyaluronan written by Hari G. Garg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-14 with Science categories.
It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. Comprehensive look at the chemistry and biology of hyaluronans Essential to Chemists, Biochemists and Medical researchers Broad yet detailed review of this rapidly growing research area
Hyaluronic Acid In Ophthalmology
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Author : Helmut Rudolf Höh
language : en
Publisher:
Release Date : 2005
Hyaluronic Acid In Ophthalmology written by Helmut Rudolf Höh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Hyaluronic Acid
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Author : Vittorio Unfer
language : en
Publisher: Nova Science Publishers
Release Date : 2021
Hyaluronic Acid written by Vittorio Unfer and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Hyaluronic acid categories.
"This book offers a valuable clinical resource for health professionals and researchers. It gives an overview about the pivotal role played by High Molecular Hyaluronic Acid (HMW-HA) during pregnancy and its applications in the gestational period. Hyaluronic acid is a critical component of the extracellular matrix (ECM) and one of the most interesting, versatile and useful natural molecules in almost all areas of biology. As widely reported, HA has a pivotal role in several phases of pregnancy, from fertilization to labour and it displays several regulatory activities and functional properties based on its different molecular weight. While low molecular weight hyaluronic acid (LMW-HA) is widely used in gynaecology for menopause-related symptoms or in association with physical treatments (e.g., radiation therapy) to counteract the onset of adverse events, HMW-HA has been poorly evaluated as clinical treatment. Its physiological presence in the extracellular matrix of all the main organs and tissues involved in pregnancy (uterus, cervix, placenta, decidua, chorion, amnios, ovarium etc..) suggests the importance of this molecule for a successful gestation. Several papers, in particular, shed light on its importance for blastocyst adhesion and implantation, for an efficient immune tolerance and for the correct development of haemo-lymphatic system. It has been demonstrated that HMW-HA has regulatory activity on the PGRMC1 expression, a specific progesterone receptor expressed in maternal and foetal-maternal interface tissues, involved in uterine quiescence. On these premises, the administration of HMW-HA may represent an interesting treatment opportunity for the prevention of recurrent miscarriage and pre-term birth (PTB) in patients with risk factors. The high safety profile of HMW-HA further supports its administration in pregnancy. All these interesting topics will be discussed and deepened in this book, giving the opportunity to explore in detail every aspect of this effective and attractive molecule, thus helping physicians to assess the state of connective tissues in pregnancy and to evaluate the risk for the onset of gestational complications"--