Hypothalamic Pituitary Disease And Obesity


Hypothalamic Pituitary Disease And Obesity
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Hypothalamic Pituitary Disease And Obesity


Hypothalamic Pituitary Disease And Obesity
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Author : D. R. Clemmons
language : en
Publisher:
Release Date : 2009

Hypothalamic Pituitary Disease And Obesity written by D. R. Clemmons and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Hypothalamic-pituitary-adrenal axis categories.




Hypothalamic Pituitary Development


Hypothalamic Pituitary Development
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Author : Raphaël Rappaport
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2001-01-01

Hypothalamic Pituitary Development written by Raphaël Rappaport and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-01 with Medical categories.


In recent years dramatic progress has been made in understanding the pathophysiology of pituitary diseases by a combination of experimental studies, molecular genetics and clinical research. This book presents an updated overview of normal and pathological hypothalamic-pituitary development. Several chapters include experimental data and describe brain and facial defects associated with various conditions of pituitary insufficiency. A major part is devoted to the still increasing number of molecular and genetic defects which are responsible for various clinical presentations of pituitary insufficiency: diseases due to genetic defects of growth hormone, TSH, gonadotropins and corticotropin secretion are extensively described. These diseases present as metabolic (diabetes insipidus and adrenal insufficiency), growth and reproductive (including puberty) disorders. A distinct chapter emphasizes the contribution of a multidisciplinary comprehensive approach including the most recent molecular and genetic tools. Finally in most chapters an effort was made to address phenotypic and genotypic presentations in affected patients including valuable information provided by magnetic resonance imaging of the pituitary and brain. This book will help endocrinologists and paediatricians by providing unique models of genetic and developmental defects of the pituitary region which bear ultimate consequences on metabolic control, growth and reproduction.



Pituitary Disorders Of Childhood


Pituitary Disorders Of Childhood
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Author : Brenda Kohn
language : en
Publisher: Springer
Release Date : 2019-03-27

Pituitary Disorders Of Childhood written by Brenda Kohn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-27 with Medical categories.


This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.



Hypothalamic Pituitary Diseases


Hypothalamic Pituitary Diseases
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Author : Felipe F. Casanueva
language : en
Publisher: Springer
Release Date : 2018-04-13

Hypothalamic Pituitary Diseases written by Felipe F. Casanueva and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-13 with Medical categories.


This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.



Pituitary Disorders Throughout The Life Cycle


Pituitary Disorders Throughout The Life Cycle
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Author : Susan L. Samson
language : en
Publisher: Springer Nature
Release Date : 2022-08-25

Pituitary Disorders Throughout The Life Cycle written by Susan L. Samson and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-25 with Medical categories.


The pituitary gland is often referred to as the master gland, coordinating hormonal signals from the hypothalamus and peripheral circulation to maintain homeostasis in the body. Patients with pituitary dysfunction are faced with challenges unique to each stage of their life cycle. For example, the goals of management for a hypopituitary adolescent transitioning to adulthood would be to optimize growth and sexual development. In early adulthood, approaches that optimize of fertility in men and women can be a priority, and the management approach will be very different from that of older adults requiring sex hormone replacement. This case-based guide will provide practical clinical guidance on approaches to the management of pituitary disorders organized by time of life, from childhood and fertile years through to older age. Sensibly divided into sections, various pituitary disorders and conditions are described and relevant treatment strategies are outlined. Sections included discussions of the unique considerations for the pituitary gland in childhood and adolescents, patients desiring fertility and pregnant patients, health optimization and non-tumoral diagnoses in adults, and management of disorders of the hypothalamic-pituitary axis in the elderly. Each chapter presents a clinical case vignette as an introduction to the concepts and a framework for the discussion of the diagnosis, management and unique consideration of each pituitary pathology. Practical and user-friendly, Pituitary Disorders throughout the Life Cycle is an excellent resource for practicing clinical endocrinologists (pediatric, transitional care, adult) and reproductive endocrinologists as well as specialty residents and trainees.



The Hypothalamic Pituitary Adrenal Axis In Health And Disease


The Hypothalamic Pituitary Adrenal Axis In Health And Disease
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Author : Eliza B. Geer
language : en
Publisher: Springer
Release Date : 2016-12-01

The Hypothalamic Pituitary Adrenal Axis In Health And Disease written by Eliza B. Geer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-01 with Medical categories.


Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.



The Hypothalamus And Pituitary In Health And Disease


The Hypothalamus And Pituitary In Health And Disease
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Author : William Locke
language : en
Publisher: Charles C. Thomas Publisher
Release Date : 1972

The Hypothalamus And Pituitary In Health And Disease written by William Locke and has been published by Charles C. Thomas Publisher this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Medical categories.




The Pituitary


The Pituitary
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Author : Shlomo Melmed
language : en
Publisher: Academic Press
Release Date : 2010-12-09

The Pituitary written by Shlomo Melmed and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-09 with Medical categories.


The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. Presents a comprehensive, translational source of information about the pituitary in one reference work Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches



The Human Hypothalamus


The Human Hypothalamus
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Author : Gabriel I. Uwaifo
language : en
Publisher: Springer Nature
Release Date : 2020-12-24

The Human Hypothalamus written by Gabriel I. Uwaifo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-24 with Medical categories.


The hypothalamus is an anatomically small but functionally important part of the brain. In functional and pathophysiological terms, the hypothalamus represents the intersection of several areas of clinical and medical expertise. The human hypothalamus can be astutely referred to as the crossroad of endocrinology, psychiatry, neurology and neurosurgery. Because of its involvement in myriad physiologic functions and the varied ways disorders involving it can manifest, hypothalamic disease can initially come to medical attention in widely disparate settings and with widely different clinicians. Therefore, the detection and proper care of hypothalamic dysfunction and disease often requires carefully coordinated multidisciplinary care. This volume fills a significant void in the medical professional community, comprehensively presenting the scope of hypothalamic structure, function, dysfunction and disease to cater to the various clinical, teaching and research professionals that have a stake in this part of the human brain. This text captures in one place all the information that practicing clinicians, clinician scientists, and researchers need to be adequately informed about various aspects of the hypothalamus in all its complexity. It is comprehensive and broad in scope so that it provides relevant reference information for the wide range of professionals involved in the pre- and post-mortem detection, diagnosis, characterization, care and management of various hypothalamic disorders and diseases in addition to providing a sound anatomic and physiologic foundation of the normal human hypothalamus. The Human Hypothalamus can be used to differing degrees by medical professionals and students alike, finding utility for interested general clinicians, medical school and allied health professional teaching faculty as well as subspecialists in domains as wide as neurosurgery, neuroendocrinology, clinical psychiatry and neuro-oncology.



Evidence Based Endocrinology


Evidence Based Endocrinology
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Author : Pauline M. Camacho
language : en
Publisher:
Release Date : 2015-04-24

Evidence Based Endocrinology written by Pauline M. Camacho and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-24 with Electronic books categories.


This pocket-sized quick-reference handbook presents evidence-based recommendations for diagnosis and treatment of endocrine disorders. The authors summarize the latest and best clinical studies supporting the practice recommendations and grade each study to indicate the benefits and risks of the therapy and the reliability of the study results. Chapters cover disorders in the major areas of endocrinology--hypothalamic-pituitary, thyroid, adrenal, metabolic bone, reproductive, diabetes, lipid disorders, obesity and nutrition, endocrine malignancies, and genetics.