Immune Cell Migration In Health And Disease


Immune Cell Migration In Health And Disease
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Immune Cell Migration In Health And Disease


Immune Cell Migration In Health And Disease
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Author : Hélène D. Moreau
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-04

Immune Cell Migration In Health And Disease written by Hélène D. Moreau and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-04 with Medical categories.




Lymphocyte Trafficking In Health And Disease


Lymphocyte Trafficking In Health And Disease
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Author : Raffaele Badolato
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-09-05

Lymphocyte Trafficking In Health And Disease written by Raffaele Badolato and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-05 with Medical categories.


This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.



Cell Migration In Development Health And Disease


Cell Migration In Development Health And Disease
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Author : Anke Brüning-Richardson
language : en
Publisher: Springer
Release Date : 2024-10-18

Cell Migration In Development Health And Disease written by Anke Brüning-Richardson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-18 with Science categories.


This textbook gives an insight into the importance of cell migration in health during development, wound healing and immune responses as well as in disease with particular focus on cancer. The reader will learn about the different ways cells migrate to allow cellular changes during development to occur, as well as responses to injury and threat by foreign invaders. Cell migration is a driver of invasion and ultimately metastasis in cancer and as such we will give examples from highly aggressive cancer such as brain tumours. The book also includes an introduction to mathematical modelling to predict cell migration, information on the development of software for analysis of data generated in 2D and 3D as well as recent developments in the investigations into cell migration using 3D bioprinting. This textbook will be a great learning tool for advanced undergraduate students and Master students with the relevant science degrees such as in cell biology, developmental biology, cancer research, and tumour biology.



Janeway S Immunobiology


Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22

Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.


The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.



Myeloid Cells In Health And Disease


Myeloid Cells In Health And Disease
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Author : Siamon Gordon
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-10

Myeloid Cells In Health And Disease written by Siamon Gordon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-10 with Science categories.


The structure, functions, and interactions of myeloid cells have long been the focus of research and therapeutics development. Yet, much more remains to be discovered about the complex web of relationships that makes up the immune systems of animals. Scientists today are applying genome-wide analyses, single-cell methods, gene editing, and modern imaging techniques to reveal new subclasses of differentiated myeloid cells, new receptors and cytokines, and important interactions among immune cells. In Myeloid Cells in Health and Disease: A Synthesis, Editor Siamon Gordon has assembled an international team of esteemed scientists to provide their perspectives of myeloid cells during innate and adaptive immunity. The book begins by presenting the foundational research of Paul Ehrlich, Elie Metchnikoff, and Donald Metcalf. The following chapters discuss evolution and the life cycles of myeloid cells; specific types of differentiated myeloid cells, including macrophage differentiation; and antigen processing and presentation. The rest of the book is organized by broad topics in immunology, including the recruitment of myeloid and other immune cells following microbial infection the role of myeloid cells in the inflammation process and the repair of damaged tissue the vast arsenal of myeloid cell secretory molecules, including metalloproteinases, tumor necrosis factor, histamine, and perforin receptors and downstream signaling pathways that are activated following ligand-receptor binding roles of myeloid cells during microbial and parasite infections contributions of myeloid cells in atherosclerosis myeloid-derived suppressor cells in tumor development and cancer Myeloid Cells in Health and Disease: A Synthesis will benefit graduate students and researchers in immunology, hematology, microbial pathogenesis, infectious disease, pathology, and pharmacology. Established scientists and physicians in these and related fields will enjoy the book's rich history of myeloid cell research and suggestions for future research directions and potential therapies.



Lymphocyte Trafficking In Health And Disease


Lymphocyte Trafficking In Health And Disease
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Author : Raffaele Badolato
language : en
Publisher: Birkhäuser
Release Date : 2009-09-03

Lymphocyte Trafficking In Health And Disease written by Raffaele Badolato and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-03 with Medical categories.


This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.



Lymphocyte Trafficking In Health And Disease


Lymphocyte Trafficking In Health And Disease
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Author : Raffaele Badolato
language : en
Publisher: Birkhäuser
Release Date : 2006-07-18

Lymphocyte Trafficking In Health And Disease written by Raffaele Badolato and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-18 with Medical categories.


This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.



Cell Migration In Inflammation And Immunity


Cell Migration In Inflammation And Immunity
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Author : Daniele D’Ambrosio
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Cell Migration In Inflammation And Immunity written by Daniele D’Ambrosio and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.


Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response to inflammatory stimuli are involved in a plethora of biological processes. These small secreted proteins exert their exquisitely variegated functions upon binding to a family of seven-transmembrane spanning G-protein coupled receptors (GPCRs) composed of almost 20 distinct entities. The biological activities of chemokines range from the control of leukocyte trafficking in basal and inflammatory conditions to the regulation of hema- poiesis, angiogenesis, tissue architecture, and organogenesis. The basis for such diversified activities rests, on one hand, upon the ubiquitous nature of chemokine production and chemokine receptor expression. Virtually every cell type can produce chemokines and expresses a unique combination of chemokine receptors. On the other hand, chemokine receptors make use of a flexible and complex network of intracellular signaling machineries that can regulate a variety of cellular functions ranging from cell migration, growth, and differentiation to death. As knowledge of the size of chemokine and chemokine receptor families rapidly reaches completeness, much is still to be uncovered in terms of fu- tional architecture of the chemokine system. The disparity between the large number of chemokines and that smaller number of receptors is balanced by the promiscuity in ligand–receptor interactions, with multiple chemokines binding to the same receptor and several chemokines binding to more than one receptor.



Cell Movement In Health And Disease


Cell Movement In Health And Disease
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Author : Michael Schnoor
language : en
Publisher: Academic Press
Release Date : 2022-03-30

Cell Movement In Health And Disease written by Michael Schnoor and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-30 with Science categories.


Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book. Combines Biology, Physics and Modeling of cellular movement in one single source Updated with the current understanding of the field Includes key research methods for cell movement investigation Cover translational aspects of cellular movement



Cell Migration In Inflammation And Immunity


Cell Migration In Inflammation And Immunity
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Author : Daniele D'Ambrosio
language : en
Publisher:
Release Date : 2003

Cell Migration In Inflammation And Immunity written by Daniele D'Ambrosio and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.


Cell migration is now well recognized as a critical component of the inflammatory disease process, so that its proper understanding promises to generate both ground-breaking basic discoveries and the development of novel therapeutics. In Cell Migration in Inflammation and Immunity: Methods and Protocols, leading cell biologists and immunologists present their most widely useful and innovative techniques for studying the molecular and cellular basis of this phenomenon. Describing each method in step-by-step detail, the authors provide a series of focused, cutting-edge techniques proceeding from the in vitro analysis of cell migration and the molecular mechanisms underlying this process, to methodologies for the analysis of cell migration in vivo. Methods for the analysis of rapid leukocyte adhesion under flow conditions in vitro are described, which may prove especially fruitful for scientists exploring the molecular mechanisms underlying both vascular recognition and leukocyte-endothelium interaction. Experimental approaches useful in establishing the role of cell migration in the pathogenesis of both acute and chronic inflammatory diseases are emphasized. Each fully tested protocol includes an introduction explaining the principle behind the technique, equipment and reagent lists, and tips on troubleshooting and how to avoid known pitfalls. Comprehensive and cutting-edge, Cell Migration in Inflammation and Immunity: Methods and Protocols offers novice and experienced investigators alike a collection of powerful techniques for studying the molecular basis and pathophysiological significance of cell migration in inflammatory and immune diseases, as well as for the development of novel therapeutics.