Immunogenetics And Immunodeficiency
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Immunogenetics And Immunodeficiency
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Author : B. Benacerraf
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunogenetics And Immunodeficiency written by B. Benacerraf and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The identification of the genes which determine biological phenomena, and the study of the control they exert on these phenomena, has proven to be the most successful approach to a detailed understanding of their mechanism. The greatest advances in molecular biology have relied upon the application of the methodology of genetics to the elucidation of the fundamental processes of life at the cellular level. The same statement may be made concerning our understanding of im munological phenomena. The genetic approach has again proven extremely productive and has permitted us to identify many fundamental questions in im munobiology and to resolve some of them successfully. Among the problems with which the young discipline of immunogenetics has been concerned are the structural genes of the immunoglobulin chains. These genes have been iden tified by their control of allotypic antigenic determinants on the constant seg ment of H chains of different classes, on the constant segments of L chains and on both the constant and variable regions of rabbit H chains. These studies have provided the first evidence for the control of a single polypeptide chain by two distinct structural genes. Much has been learned concerning the genes coding the C and V regions of immunoglobulin chains (a) from the study of the inheritance of allotypic and idiotypic determinants on these chains discussed by Kunkel and Kindt and (b) from the analysis of the amino acid sequence in immunoglobulin chains from individual myeloma proteins and abnormal paraproteins, discussed by Frangione.
Human Immunogenetics
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Author : Jaime E. Bernal
language : en
Publisher: Taylor & Francis US
Release Date : 1986
Human Immunogenetics written by Jaime E. Bernal and has been published by Taylor & Francis US this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Health & Fitness categories.
Inborn Errors Of Immunity And Phagocytosis
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Author : F. Güttler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Inborn Errors Of Immunity And Phagocytosis written by F. Güttler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The rapid growth of immunology has greatly increased our understanding of disease; this growth has also generated a subject which at times appears separated from some of the basic medical sciences. Recent studies in the areas of purine metabolism and of polymorphonuclear neutrophil phago cyte function have, however, linked immunology and clinical medicine with biochemistry. The precise defects of the inborn errors of metabolism have now provided good evidence for the importance of purine metabolism specifically the enzymes adenosine deaminase and nucleoside phosphorylase in lymphocyte function. In view of this and the steady advance of clinical and biochemical investigation of the polymorphonuclear neutrophil phago cyte, it appeared timely to review the inborn errors of immunity and phagocytosis at the fifteenth annual symposium of the Society for the Study of Inborn Errors of Metabolism at Elsinore, Denmark on September II-14th, I~77. The papers presented at that meeting form the basis of this volume which brings together contributions from immunologists, biochemists and clinicians. This interdisciplinary communication should be helpful to those concerned with immune function in their patients or in the laboratory. The book is divided into four sections, One: defects of cell-mediated immunity, Two: enzyme defects and immunodeficiency, Three: disorders of non-specific immunity and Four: screening for immunodeficiency. Section One contains two reviews, one on immunodeficiency from Robert Good's group in New York and another on the genetics of the immune system from Arne Svejgaard of Copenhagen.
The Immune System
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Author : Gino Doria
language : en
Publisher:
Release Date : 1980
The Immune System written by Gino Doria and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Immune response categories.
Immunogenetics Of Fungal Diseases
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Author : Agostinho Carvalho
language : en
Publisher: Springer
Release Date : 2017-04-03
Immunogenetics Of Fungal Diseases written by Agostinho Carvalho and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-03 with Medical categories.
This book provides up-to-date information on immunogenetics of fungal diseases in the context of primary and acquired immunodeficiencies. Different aspects of this emerging field are covered, including epidemiology of fungal diseases, innate and adaptive antifungal immunity, and the role of immunogenetics in defining susceptibility to fungal diseases in primary (CMC, CGD, etc.) immunodeficiencies and hematologic patients. The available information will also be discussed in the scope of new biomarker discovery and development of immunotherapeutic approaches for personalized diagnostics and therapy. The book addresses Professors, researchers and advanced students of Medicine, Immunology, Microbiology and Genetics.
Human Immunogenetics
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Author : S. D. Litwin
language : en
Publisher: CRC Press
Release Date : 1989-01-10
Human Immunogenetics written by S. D. Litwin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-01-10 with Science categories.
Delineating fundamental concepts of contemporary immunogenetics, this reference/text examines specific immunogenetic systems in terms of molecular biochemistry and immunophysiology. Covers material in diverse fields, including infectious diseases, cell biology, virology, molecular genetics. Comprise
Genetic Control Of The Susceptibility To Bacterial Infection
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Author : David E. Briles
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Genetic Control Of The Susceptibility To Bacterial Infection written by David E. Briles and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Primary Immunodeficiency Diseases
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Author : Hans D. Ochs, MD, Dr.med
language : en
Publisher: Oxford University Press
Release Date : 2013-11-01
Primary Immunodeficiency Diseases written by Hans D. Ochs, MD, Dr.med and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-01 with Medical categories.
Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options -- from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy -- this volume will remain an authoritative resource on this increasingly important area.
The Immunogenetics Of Autoimmune Diseases
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Author : Nadir R. Farid
language : en
Publisher: CRC Press
Release Date : 1990-11-21
The Immunogenetics Of Autoimmune Diseases written by Nadir R. Farid and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-21 with Medical categories.
Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex
Immunology
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Author : Klaus D. Elgert
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-08
Immunology written by Klaus D. Elgert and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-08 with Medical categories.
Blends biology, clinical science, genetics, and molecular biology of the immune system to provide a complete account of our knowledge of immunology New features include full-color artwork and design, over 50 new figures, and text that has been completely revised to reflect the very latest references Incorporates a variety of pedagogical aids to assist students in the learning process, including chapter outlines, objectives, and summaries, as well as a self-evaluation section