Immunoglobulin Glycosylation Analysis State Of The Art Methods And Applications In Immunology
DOWNLOAD
Download Immunoglobulin Glycosylation Analysis State Of The Art Methods And Applications In Immunology PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Immunoglobulin Glycosylation Analysis State Of The Art Methods And Applications In Immunology book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Immunoglobulin Glycosylation Analysis State Of The Art Methods And Applications In Immunology
DOWNLOAD
Author : Irena Trbojević-Akmačić
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-14
Immunoglobulin Glycosylation Analysis State Of The Art Methods And Applications In Immunology written by Irena Trbojević-Akmačić and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-14 with Medical categories.
Antibody Glycosylation
DOWNLOAD
Author : Marija Pezer
language : en
Publisher: Springer Nature
Release Date : 2021-10-22
Antibody Glycosylation written by Marija Pezer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-22 with Medical categories.
This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Glycosylation Analysis Of Immunoglobulin G
DOWNLOAD
Author : Maurice Henricus Johnannes Selman
language : en
Publisher:
Release Date : 2012
Glycosylation Analysis Of Immunoglobulin G written by Maurice Henricus Johnannes Selman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Capillary Gel Electrophoresis
DOWNLOAD
Author : Andras Guttman
language : en
Publisher: Newnes
Release Date : 2021-12-04
Capillary Gel Electrophoresis written by Andras Guttman and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-04 with Science categories.
Capillary Gel Electrophoresis and Related Microseparation Techniques covers all theoretical and practical aspects of capillary gel electrophoresis. It also provides an excellent overview of the key application areas of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods. It not only gives readers a better understanding of how to utilize this technology, but also provides insights into how to determine which method will provide the best technical solutions to particular problems. This book can also serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses. Covers all theoretical and practical aspects of capillary gel electrophoresis Excellent overview of the key applications of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods Teaches readers how to use the technology and select methods that are ideal for fundamental problems Can serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses
Chronic Graft Versus Host Disease
DOWNLOAD
Author : Georgia B. Vogelsang
language : en
Publisher: Cambridge University Press
Release Date : 2009-04-20
Chronic Graft Versus Host Disease written by Georgia B. Vogelsang and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-20 with Medical categories.
Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant.
State Of The Art And Emerging Technologies For Therapeutic Monoclonal Antibody Characterization Volume 2 Biopharmaceutical Characterization
DOWNLOAD
Author : John E. Schiel
language : en
Publisher: ACS Symposium
Release Date : 2016-06-24
State Of The Art And Emerging Technologies For Therapeutic Monoclonal Antibody Characterization Volume 2 Biopharmaceutical Characterization written by John E. Schiel and has been published by ACS Symposium this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-24 with Medical categories.
"Distributed in print by Oxford University Press."
Biosimilars Of Monoclonal Antibodies
DOWNLOAD
Author : Cheng Liu
language : en
Publisher: John Wiley & Sons
Release Date : 2016-12-09
Biosimilars Of Monoclonal Antibodies written by Cheng Liu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-09 with Medical categories.
Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing. • Guides readers through the complex landscape involved with developing biosimilar versions of monoclonal antibody (mAb) drugs • Features flow charts, tables, and figures that clearly illustrate processes and makes the book comprehensible and accessible • Includes a review of FDA-approved mAb drugs as a quick reference to facts and useful information • Examines new technologies and strategies for improving biosimilar mAbs
Progress In Molecular Biology And Translational Science
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2019-03-22
Progress In Molecular Biology And Translational Science written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-22 with Science categories.
Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer Biology and Its Clinical Applications, Retrospective Analysis of Glycan-Related Biomarkers Based on Clinical Laboratory Data in Two Medical Centers, and many related topics. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field
Immunology Laboratory Testing An Issue Of The Clinics In Laboratory Medicine
DOWNLOAD
Author : Vinay Subash Mahajan
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-11-02
Immunology Laboratory Testing An Issue Of The Clinics In Laboratory Medicine written by Vinay Subash Mahajan and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-02 with Medical categories.
This issue of Clinics in Laboratory Medicine, guest edited by Dr. Vinay Subhash Mahajan, will focus on Immunology Laboratory Testing. Topics include, but are not limited to, Analysis of proteins and immunoglobulins in the clinical immunology laboratory; Antinuclear antibody tests; Serological diagnosis of rheumatoid arthritis; ANCA; Anti-phospholipid antibodies; Diagnostic pitfalls in autoantibody testing; Analysis of the complement pathway; Flow cytometric analysis of immune cell subsets; Testing of cellular immune function in immunodeficiencies; Food allergy testing; Evaluation of the immune response in transplantation; Laboratory testing in the context of biologics and cellular therapies; Testing immune-related adverse-events in cancer immunotherapy; Molecular diagnosis of inherited immune disorders; and Future of immunology lab testing.
Glycosylation Engineering Of Biopharmaceuticals
DOWNLOAD
Author : Alan Beck
language : en
Publisher: Humana Press
Release Date : 2013-03-09
Glycosylation Engineering Of Biopharmaceuticals written by Alan Beck and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals.