Immunolocalization And Evaluation Of Thioredoxin Glutathione Reductase Role In Diagnosis Of Human Schistosomiasis
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Immunolocalization And Evaluation Of Thioredoxin Glutathione Reductase Role In Diagnosis Of Human Schistosomiasis
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Author : Azza El Amir
language : en
Publisher: GRIN Verlag
Release Date : 2014-11-06
Immunolocalization And Evaluation Of Thioredoxin Glutathione Reductase Role In Diagnosis Of Human Schistosomiasis written by Azza El Amir and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-06 with Medical categories.
Doctoral Thesis / Dissertation from the year 2003 in the subject Biology - Parasitology, grade: PhD, Cairo University (Faculty of Science.), course: Immunoparasitology, language: English, abstract: Schistosoma parasite continued to be focus of the solicitude investigators to control the prevalence of the parasite. The efforts are needed for sensitive and accurate diagnosis that can utilize to rapidly map the prevalence of the disease. Our study aimed to benefit from the necessity of the S. mansoni for enzyme TGR, in utilization of the enzyme as an antigen target and evaluate its efficacy in the diagnosis of S. mansoni infection patients. The results revealed that smTGR could be detected in various organs of infected mice and localized in all parasites life cycle stages except eggs using smTGR pAb. Sandwich ELISA reveled that this antigen can be relied as a diagnostic antigen target in serum and urine.
Special Topics In Drug Discovery
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Author : Taosheng Chen
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-11-30
Special Topics In Drug Discovery written by Taosheng Chen and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-30 with Medical categories.
Drug discovery involves multiple disciplines, technologies, and approaches. This book selects important topics related to drug discovery, including emerging tool (Chapter 1), cutting-edge approaches (Chapters 2, 3, and 4), examples of specific therapeutic area (Chapter 5), quality control in drug development (Chapter 6), and job and career opportunities in the pharmaceutical sector, a topic rarely covered by other books (Chapter 7). This book draws knowledge from experts actively involved in different areas of drug discovery from both industrial and academic settings. We hope that this book will facilitate your efforts in drug discovery.
Performance Evaluation Of Idma Scheme In Wireless Communication
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Author : Manoj Shukla
language : en
Publisher: GRIN Verlag
Release Date : 2014-07-14
Performance Evaluation Of Idma Scheme In Wireless Communication written by Manoj Shukla and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-14 with Computers categories.
Doctoral Thesis / Dissertation from the year 2011 in the subject Computer Science - Internet, New Technologies, grade: 10.00, , course: Ph.D., language: English, abstract: As per recommendations of International Mobile Telecommunications-2000 (IMT-2000), the future wireless communication is bound to occupy the features including high-speed data and broadband transmission, high capacity to support a huge number of simultaneous users, global mobility, high security, and scalable quality of service (QoS) along with low cost for both operators and subscribers. The above features are imposing technical challenges on system design and stimulating various research topics on capacity, complexity and performance. In order to increase the capacity of wireless networks, various multiple access schemes have been reported in the literature. The credit of most competent multiple access scheme in 2G systems goes to CDMA scheme which offers an even better bandwidth-efficiency than TDMA and FDMA schemes, however, its implementation is quite difficult due to involvement of rather complex technologies including complex power-control, and multiuser detection techniques etc. The requirement of alternate mechanism for user separation has been solved by Interleave-Division Multiple-Access (IDMA) scheme, in which, most of above stated problems do not exist due to application of user-specific interleavers having low cross-correlation amongst them. The interleaved data resulted from user-specific interleavers, demonstrates better orthogonality amongst each other in the channel. The condition of orthogonality is maintained for reducing the risk of collision amongst the interleavers during communication process. In IDMA scheme, orthogonal interleavers are employed as the only means for user separation and, hence, are referred as the heart of the scheme. The selection of interleaver along with optimum design methodology for proposed tree based interleaving (TBI) mechanism for IDMA scheme fulfilling the requirement of orthogonality and easy implementation. In the beginning of work, the mechanism of interleaving with necessary conditions is presented. Later, the performance and analysis of proposed TBI mechanism with IDMA scheme has been presented. Apart from the bit error rate (BER) performance analysis, the interleavers have also been analyzed on the basis of memory requirement and computational complexity at transmitter and receiver ends. Here, The performance evaluation of IDMA scheme with proposed tree based interleaving (TBI) mechanism, in uncoded and coded environments, has been duly investigated along with its implementation.
Eukaryome Impact On Human Intestine Homeostasis And Mucosal Immunology
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Author : Nancy Guillen
language : en
Publisher: Springer Nature
Release Date : 2020-06-01
Eukaryome Impact On Human Intestine Homeostasis And Mucosal Immunology written by Nancy Guillen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-01 with Medical categories.
Multiple demographic or economic parameters contribute to the origin of emerging infections, for example: poverty, urbanization, climate change, conflicts and population migrations. All these factors are a challenge to assess the impact (present and future) of parasitic diseases on public health. The intestine is a major target of these infections; it is a nutrient-rich environment harbouring a complex and dynamic population of 100 trillion microbes: the microbiome. Most researches on the microbiome focus on bacteria, which share the gut ecosystem with a population of uni- and multi cellular eukaryotic organisms that may prey on them. Our interest focuses on the families of eukaryotic microbes inhabiting the intestine, called “intestinal eukaryome”, that include fungi, protists and helminths. Knowledge on the reciprocal influence between the microbiome and the eukaryome, and on their combined impact on homeostasis and intestinal diseases is scanty and can be considered as an important emerging field. Furthermore, the factors that differentiate pathogenic eukaryotes from commensals are still unknown. This book presents an overview of the science presented and discussed in the First Eukaryome Congress held from October 16th to 18th, 2019 at the Pasteur Institute in Paris. This book covers the following topics: Phylogenetic, prevalence, and diversity of intestinal eukaryotic microbes; and their (still enigmatic) historical evolution and potential contributions to mucosal immune homeostasis. Integrative biology to study the molecular cell biology of parasite-host interactions and the multiple parameters underlining the infectious process. The exploitation of tissue engineering and microfluidics to establish three-dimensional (3D) systems that help to understand homeostasis and pathological processes in the human intestine.
Fasciolosis Causes Challenges And Controls
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Author : Dinesh Kumar Singh
language : en
Publisher: Springer Nature
Release Date : 2021-03-30
Fasciolosis Causes Challenges And Controls written by Dinesh Kumar Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-30 with Medical categories.
This book provides an up-to-date review of fasciolosis, a disease caused by Fasciola hepatica and Fasciola gigantica, including its biology, transmission, epidemiology, host distribution, economic impact, and novel approaches for its diagnosis, treatment and prevention. It first offers a brief overview of the history of the disease, the genetic diversity of the parasite and its distribution, and the ecology of the vector snail, which belongs to the Lymnaeidae/Planorbidae family. It also examines the current strategies and novel approaches for controlling the parasite, diagnosing infections and vaccine development. Importantly, it highlights issues relating to the control of fasciolosis, including drug resistance, lack of effective diagnostics, and the parasite’s long-term survival strategies based on regulation and modulation of the host immune system. Lastly, it discusses the novel control snail vectors using bait formulations, and synergetic and phototherapy treatment with chlorophyllin, which does not kill the vector.
Human Schistosomiasis
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Author : Peter Jordan
language : en
Publisher: Oxford University Press, USA
Release Date : 1993
Human Schistosomiasis written by Peter Jordan and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
Human schistosomes (blood flukes) are digenetic trematodes that spend the adult part of their life cycle in humans and a further part in aquatic snails. Despite advances in chemotherapy, schistosomiasis is still a significant infection in the populations of several countries in the tropics. This book replaces a previous volume Schistosomiasis: Epidemiology, Treatment and Control (Heinemann, 1982) by Jordan and Webbe. All chapters have been rewritten by internationally renowned workers. Ultrasound, expected to aid identification of early disease in the field and increase our understanding of its evolution, is discussed in a new chapter. Others, each with an extensive bibliography, review the parasites and their snail intermediate hosts, epidemiology, clinical manifestations and pathology, diagnosis, immunology, drugs and patient management and control. Limitations of the role of chemotherapy in morbidity control are discussed and the need for flexibility in control interventions in the varied epidemiological situations is stressed. An interdisciplinary approach may be necessary to reduce transmission by appropriate measures against the snail intermediate host, and to implement public health measures, including the provision of safe water (with many other medical and social benefits) and health education. This comprehensive volume is for public health workers involved in the prevention and control of the disease, for physicians, and for students and teachers of many disciplines. It also provides a reference book for health planners, social anthropologists, health educators, water and sanitary engineers and others engaged in improving health in the tropics. Physicians in temperate countries will also find it a useful reference book as schistosomiasis, often acute, is being diagnosed more frequently in those returning from holidays in endemic areas.
Basic Exercises In Immunochemistry
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Author : A. Nowotny
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Basic Exercises In Immunochemistry written by A. Nowotny and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Oxidative Stress In Microbial Diseases
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Author : Sajal Chakraborti
language : en
Publisher: Springer
Release Date : 2019-11-12
Oxidative Stress In Microbial Diseases written by Sajal Chakraborti and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-12 with Science categories.
This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.
Digenetic Trematodes
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Author : Rafael Toledo
language : en
Publisher: Springer
Release Date : 2014-06-05
Digenetic Trematodes written by Rafael Toledo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-05 with Medical categories.
Digenetic trematodes constitute a major helminth group that parasitize humans and animals, and are a major cause of morbidity and mortality. The diseases caused by trematodes have been neglected for years, especially as compared with other parasitic diseases. However, the geographical limits and the populations at risk are currently expanding and changing in relation to factors such as growing international markets, improved transportation systems, and demographic changes. This has led to a growing international interest in trematode infections, although factors such as the difficulties entailed in the diagnosis, the complexity of human and agricultural practices, the lack of assessments of the economic costs or the limited number of effective drugs are preventing the development of control measures of these diseases in humans and livestock. In-depth studies are needed to clarify the current epidemiology of these helminth infections and to identify new and specific targets for both effective diagnosis and treatments. The main goal of this book is to present the major trematodes and their corresponding diseases in the framework of modern parasitology, considering matters such as the application of novel techniques and analysis of data in the context of host-parasite interactions and to show applications of new techniques and concepts for the studies on digenetic trematodes. This is an ideal book for parasitologists, microbiologists, zoologists, immunologists, professional of public health workers, clinicians and graduate and post-graduate students.
The Geohelminths
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Author : Celia V. Holland
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
The Geohelminths written by Celia V. Holland and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Science categories.
The soil-transmitted nematode parasites, or geohelminths, are - called because they have a direct life cycle, which involves no intermediate hosts or vectors, and are transmitted by faecal contamination of soil, foodstuffs and water supplies. They all inhabit the intestine in their adult stages but most species also have tissue-migratoryjuvenile stages, so the disease manifestations they cause can therefore be both local and systemic. The geohelminths together present an enormous infection burden on humanity. Those which cause the most disease in humans are divided into three main groupings, Ascaris lumbricoides (the large roundworm), Trichuris trichiura (whipworm), and the blood-feeding hookworms (Ancylostoma duodenale and Necator americanus ), and this book concentrates on these. These intestinal parasites are highly prevalent worldwide, A. lumbricoides is estimated to infect 1471 million (over a quarter ofthe world’s population), hookworms 1277 million, and T. trichiura 1049 million. The highly pathogenic Strongyloides species might also be classified as geohelminths, but they are not dealt with here because the understanding of their epidemiology, immunology and genetics has not advanced as rapidly as for the others. This is primarily because of the often covert nature of the infections, with consequent difficulties for analysis. If there is ever a second edition of this book, then there will hopefully be much to say about this infection.