Immunological Studies On The Curing Of A Persistent Viral Infection
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Persistent Viral Infections
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Author : R. Ahmed
language : en
Publisher: Wiley-Blackwell
Release Date : 1999
Persistent Viral Infections written by R. Ahmed and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.
Immunological Studies On The Curing Of A Persistent Viral Infection
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Author : Beth D. Jamieson
language : en
Publisher:
Release Date : 1989
Immunological Studies On The Curing Of A Persistent Viral Infection written by Beth D. Jamieson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Cellular immunity categories.
Gene Therapy For Viral Infections
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Author : Patrick Arbuthnot
language : en
Publisher: Academic Press
Release Date : 2015-06-01
Gene Therapy For Viral Infections written by Patrick Arbuthnot and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Science categories.
Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections Bridges the gap between the basic science and the important medical applications of this technology Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs Arms the reader with the cutting-edge information needed to stay abreast of this developing field
The Immune Response
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Author : Tak W. Mak
language : en
Publisher: Academic Press
Release Date : 2005-11-11
The Immune Response written by Tak W. Mak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-11 with Medical categories.
The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. Current and thorough 30 chapter reference reviewed by luminaries in the field Unique ‘single voice' ensures consistency of definitions and concepts Comprehensive and elegant illustrations bring key concepts to life Provides historical context to allow fuller understanding of key issues Introductory chapters 1-4 serve as an ‘Immunology Primer' before topics are discussed in more detail
Hiv 1 Latency
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Author : Guido Silvestri
language : en
Publisher: Springer
Release Date : 2018-10-11
Hiv 1 Latency written by Guido Silvestri and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-11 with Medical categories.
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
What You Need To Know About Infectious Disease
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Author : Madeline Drexler
language : en
Publisher:
Release Date :
What You Need To Know About Infectious Disease written by Madeline Drexler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Novel Therapeutic Strategies For Chronic Hbv Infection An Immunological Perspective
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Author : Seung Kew Yoon
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-14
Novel Therapeutic Strategies For Chronic Hbv Infection An Immunological Perspective written by Seung Kew Yoon and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-14 with categories.
Chronic hepatitis B (CHB) is a life-threatening liver disease affecting 257 million people worldwide, in particular in the Asia-Pacific regions. In endemic areas, hepatitis B virus (HBV) is usually transmitted from chronically infected mothers to neonates. Perinatal HBV infection causes chronic infection in more than 90% of exposed individuals. With perinatal infection, lifetime mortality risk due to complications of liver cirrhosis (LC) or hepatocellular carcinoma (HCC) reaches up to 40% in men and 15% in women. For the treatment of chronic HBV infection, nucleos(t)ide analogue antivirals have been successfully used to suppress viral replication. However, HBV exists as a cccDNA, which cannot be eliminated by nucleos(t)ide analogues. Therefore, a practical goal of novel HBV therapeutics can be HBs seroconversion (loss of HBsAg and development of HBsAg-specific antibodies), which occurs during spontaneous recovery from acute HBV infection. This HBs seroconversion is referred to as “functional cure” of HBV infection. When functional cure is reached, HBsAg-specific antibodies have virus-neutralizing activity and control HBV infection even in the presence of cccDNA. Currently, peg-IFN-a is often used to induce HBs seroconversion in patients with chronic HBV infection; however, the efficacy is not satisfactory. In future, other immunological therapeutics must be considered to achieve HBs seroconversion, including therapeutic vaccines and immune checkpoint blockers.
Antiviral Chemotherapy
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Author : D. J. Jeffries
language : en
Publisher:
Release Date : 1995-07-11
Antiviral Chemotherapy written by D. J. Jeffries and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-07-11 with Medical categories.
Considerable advances have been made in the treatment of antiviral diseases over the last decade. Several new drugs have been introduced while new clinical information has been gathered on the efficacy of existing drugs. This study aims to provide an examination of the basic science (drug formulae, structure and biochemical activity) and clinical information (usage and efficacy) on chemotherapy, as well as describing future potentials.
Human Herpesviruses
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Author : Ann Arvin
language : en
Publisher: Cambridge University Press
Release Date : 2007-08-16
Human Herpesviruses written by Ann Arvin and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-16 with Medical categories.
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Insights In Viral Immunology 2021
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Author :
language : en
Publisher: Frontiers Media SA
Release Date :
Insights In Viral Immunology 2021 written by and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.