Immunology Of Aging
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Immunology Of Aging
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Author : Ahmad Massoud
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-29
Immunology Of Aging written by Ahmad Massoud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-29 with Medical categories.
The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.
Immunology And Aging
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Author : Takashi Makinodan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunology And Aging written by Takashi Makinodan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the classic sense, immunity is the ability of an organism to resist disease. On the one hand, we must distinguish between age and disease; on the other hand, the interaction between them is of considerable theoretical and practical interest. To the gerontologic research community, therefore, immunity also becomes the ability of an organism to resist age. Were the immune and other protective systems of the body able to maintain themselves over the course of time, and if there were no degradation related to age, the everyday loss of energy and vitality that occurs in the lives of older people as a consequence of viruses, arthritis, and other debilitating circumstances would be greatly lessened. The objective of gerontologists is not just to extend the life span but rather to improve the vigor, health, and quality oflife. To date, we have not developed a single index to measure immunity that is of use clinically in the evaluation of older people and of their immunologic compe tence. It may not be surprising that just such a clinical index may be available in the not-too-distant future. We can also look forward to the assembling of a greater body of information explaining how and why the immune system fails with age while, paradoxically, the incidence of autoimmune diseases increases with age. It is this latter phenomenon that may playa part in a wide range of chronic diseases from rheumatoid arthritis to senile dementia.
Stress Immunity And Aging
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Author : E. L. Cooper
language : en
Publisher: CRC Press
Release Date : 2020-07-24
Stress Immunity And Aging written by E. L. Cooper and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-24 with Psychology categories.
This book contains two personal reminiscences of historical importance to research on stress and infectious disease. It deals with perspectives on immunity, aging, and disease and the prospects for immunorestoration in the treatment of immunodeficiency arising from aging and stress.
Immunology And Ageing
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Author : N. Fabris
language : en
Publisher: Springer Science & Business Media
Release Date : 1982-03-31
Immunology And Ageing written by N. Fabris and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-03-31 with Medical categories.
Hdbk Immunology Of Aging
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Author : Marguerite M. B. Kay
language : en
Publisher: Springer
Release Date : 1981-10-27
Hdbk Immunology Of Aging written by Marguerite M. B. Kay and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-10-27 with Health & Fitness categories.
Aging And The Immune Response
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Author : Edmond A. Goidl
language : en
Publisher: Marcel Dekker
Release Date : 1987
Aging And The Immune Response written by Edmond A. Goidl and has been published by Marcel Dekker this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
Handbook Of Immunology And Aging
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Author : Isla Pierce
language : en
Publisher: Foster Academics
Release Date : 2019-06-12
Handbook Of Immunology And Aging written by Isla Pierce and has been published by Foster Academics this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-12 with Medical categories.
Immunology is a branch of biology concerned with the study of immune systems. Immunological studies have applications in the fields of oncology, organ transplantation, rheumatology, dermatology, etc. The disorders of the immune system can result in immunodeficiency diseases and autoimmune diseases. Immunodeficiency diseases are caused when the immune system fails to provide the adequate immune response. When the immune system attacks its own host's body, it leads to autoimmune diseases, some of which include rheumatoid arthritis, systemic lupus erythematosus, Hashimoto's disease, etc. The gradual accumulation of psychological, physical and social changes in a human being over time constitutes the process of aging. A less efficient immune function is a characteristic of old age. As the immune system weakens progressively with age, the organism becomes unable to fight infections and increasingly incapable of destroying old and neoplastic cells. This eventually leads to death. This book contains some path-breaking studies in immunology and aging. It unfolds the innovative aspects of the relationship between immunology and aging, which will be crucial for the understanding of these areas. The readers would gain knowledge that would broaden their perspective about these fields.
The Aging Immune System And Health
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Author : Valquiria Bueno
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-15
The Aging Immune System And Health written by Valquiria Bueno and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-15 with categories.
The world population presents an increased percentage of individuals over 65 years old and the fastest growing subgroup is over 85 years old. The increase in life expectancy observed in the last century has not been synonymous with extra years lived in good health (disability-free years). Population studies have shown that as individuals age, they can present a great heterogeneity of ability and health. Therefore, aging has been associated for some individuals with disabilities and hospitalizations. Deaths related to infectious pathogens are increased in the aging population mainly due to pneumonia and influenza whereas Cytomegalovirus, Epstein-Barr virus, among other viruses seem to contribute to the low-grade inflammatory process observed (inflammaging). Aging is a complex and multifactorial process in which functions of the organism are adjusted (remodelled) in order to deal with damaging events during life. One of the most important changes in aging individuals occurs in the immune system (innate and adaptive responses) with consequences such as poor response to new infections and vaccinations; increased susceptibility to cancer development and autoimmune diseases; frailty, and organ dysfunction. In addition, it has been proposed that immunosenescence not only reflects the aging of the organism but also contributes to this process. Bone marrow presents decreased hematopoiesis, the thymus undergoes involution and lymphoid organs (lymph nodes, spleen) also present reduced functionality. Therefore, cells derived, matured, or residing in these tissues decline in number and function. These changes have been identified in experimental models, in vitro conditions, peripheral blood, and biopsies via biomarkers such as cell phenotype, stimulus-induced proliferation, cytokines and antibodies levels. Telomere length and telomerase activity also decline in bone marrow-derived and peripheral blood cells and have been shown to play a role in immunosenescence. More recently, the investigation of short non-coding RNA molecules (microRNAs; miRNAs) pointed to this system as a possible control of aging-related mechanisms. Data obtained on these markers for aging individuals could lead to the generation of a marker panel for pathology prediction, to indicate interventions, and to evaluate the efficacy of interventions. Interventions such as nutrition supplements, exercise, vaccination (different dose, concentration of antigen, adjuvants) have been proposed to circumvent age-related diseases. Considering the heterogeneity in the aging process, further investigation is vital before the indication of interventions for aging individuals. As the extension of life expectancy is a reality, it is a challenge to understand how the aging population copes with the remodelling of the organism and how interventions could provide longevity in good health.
The Ageing Immune System And Health
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Author : Valquiria Bueno
language : en
Publisher: Springer
Release Date : 2016-10-03
The Ageing Immune System And Health written by Valquiria Bueno and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-03 with Medical categories.
The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health.
How Aging Affects T Lymphocyte Mediated Immunity
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Author : Dietmar Herndler-Brandstetter
language : en
Publisher: Frontiers Media SA
Release Date : 2015-05-07
How Aging Affects T Lymphocyte Mediated Immunity written by Dietmar Herndler-Brandstetter and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-07 with Immunologic diseases. Allergy categories.
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