Immunology Of Breast Milk
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Immunology Of Breast Milk
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Author : Pearay L. Ogra
language : en
Publisher: Raven Press (ID)
Release Date : 1979
Immunology Of Breast Milk written by Pearay L. Ogra and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Health & Fitness categories.
Abstract: The mechanisms of immunity transfer to newborns through breast milk are not clearly understood. Biochemists exchanged information relevant to the systemic and local muscosal immunity system provided to the newborn by the mammary gland and its secretions. Topics include the functions of the mucosal immune system and the gut-associated and bronchial-associated lymphoid tissues, the transfer of maternal antibodies to fetus or newborn, andthe constituents of human colostrum and milk, such as immunoglobulins M, G, A, E and D, and cells B, T, NK and K. Questions which remain unanswered include stimulus and location of B-cell switching; the origin and acquisition of T-cell recognition patterns; cell migration and binding; maternal cell colonization of the infant; the presence of lymphokines and monokines; and the roles of basophils, most cells and esinophils.
Immunology Of Milk And The Neonate
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Author : Jiri Mestecky
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunology Of Milk And The Neonate written by Jiri Mestecky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the course of history, humans have attempted to interrupt the physiological and psychological bond formed between a nursing mother and her child by substituting breastfeeding with artificial formulas. A growing body of evidence indicates that breast milk, quite apart from its unsurpassed nutritive value, contains a large number of substances that protect the offspring from common infectious agents and allergens and promote the maturation of the gastrointestinal tract and the immune system. In addition to well described milk antibodies and soluble mediators of innate immunity, milk cells and pluripotent secreted factors - cytokines - are currently in the forefront of extensive research with respect to their importance in milk immunology. The purpose of this conference was to critically evaluate the current state of our knowledge concerning the protective role of immune agents found in milk, to provide up-to-date information of milk factors with respect to their role in the maturation of immunological defense systems in the neonate, and to reassess the importance of breastfeeding in the prevention of allergies in formula-fed infants. We hope that the work presented by international participants will prompt many new ideas and stimulate further research in this important area. This conference was sponsored primarily by the National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD. We would like to thank Drs. Sumner Yaffe and Delbert Dayton for their efforts with the organization, planning, and support of this conference.
Advances In Nutritional Research Volume 10
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Author : Bill Woodward
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Advances In Nutritional Research Volume 10 written by Bill Woodward and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume of Advances in Nutritional Research focuses on colostrum and milk as agents of defense against infection both for the suckling offspring and for the lactating mammary gland. The scope of the volume includes positive and negative influences of the consumption of mother's milk on the risk of infec tion, immunobiological roles of individual milk components, activities of milk and its components in promoting development of neonatal immunocompetence, the potential of milk and its components as therapeutic agents and as functional foods that support immune competence, and external influences that determine the immunological activity of milk. The volume is intended to provide a critical assessment of the limits of available information pertaining to humans and animals, together with authoritative comment regarding newer directions and unproven ideas. Part I provides a foundation for the volume. Readers unfamiliar with immunology will find, in Chapter 1, a selective outline of the anatomy and ontogeny of the mammalian immune system and of the types and regulation of immune defenses in mammals. Some emphasis is given to the place of the mammary gland within the common mucosal defense system, and to important species peculiarities in this regard. Chapter 2 is an authoritative and forward looking perspective on the development of knowledge pertaining to the immuno biology of milk as a fluid with both anti-infectious and anti-inflammatory roles. The chapter poses the provocative possibility of a tolerogenic role for milk.
Milk Mucosal Immunity And The Microbiome Impact On The Neonate
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Author : P.L. Ogra
language : en
Publisher: S. Karger
Release Date : 2020-04-24
Milk Mucosal Immunity And The Microbiome Impact On The Neonate written by P.L. Ogra and has been published by S. Karger this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-24 with Medical categories.
Considerable advances have been made in science in order to understand the varied mixture of bioactive components in human milk. The 94th Nestlé Nutrition Institute Workshop was designed to provide a comprehensive overview of the latest findings in human milk research and its potential to modulate mucosal immunity, the microbiome, and its impact on the neonate. The publication provides a balanced state-of-the-art update on the current knowledge about milk, mucosal immunity, and the microbiome as well as their impact on breastfeeding in mammalian neonates. The first part reviews data on the immunology of milk and lactation from a historical perspective to the latest scientific findings. The second part discusses the microbiology of human milk and lactation in detail, with a focus on premature infants and necrotizing enterocolitis. And finally, in the third part, light is shed on the protective factors in human milk and their role in influencing the neonate’s immune system. Important new insights will provide great scientific support for all people seeking a deeper understanding of human milk and its immunological properties and will enlarge the knowledge of those who have already specialized in human milk research.
Stem Cell And Non Stem Cell Components Of Breast Milk
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Author : Indumathi Somasundaram
language : en
Publisher: Springer Nature
Release Date : 2023-09-02
Stem Cell And Non Stem Cell Components Of Breast Milk written by Indumathi Somasundaram and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-02 with Science categories.
This book reviews the cellular and non-cellular components of human breast milk and their contribution to infant growth and development. It also discusses various cellular growth factors in breast milk, including stem cells and their significance in promoting optimal growth, immunity and regeneration in neonates and in mitigating several neonatal diseases. Further, the book examines variations in the macronutrient concentrations of human milk in different lactation stages and maternal factors. It also describes the potential of antimicrobial proteins/peptides in human milk to provide innate immunity to infants. Lastly, it explores the regenerative therapeutic applications of breast milk cells in feeding infants.
Integrating Population Outcomes Biological Mechanisms And Research Methods In The Study Of Human Milk And Lactation
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Author : Margarett K. Davis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Integrating Population Outcomes Biological Mechanisms And Research Methods In The Study Of Human Milk And Lactation written by Margarett K. Davis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Integrating Population Outcomes, Biological Mechanisms and Research Methods in the Study of Human Milk and Lactation is the product of the 10th Conference of the International Society for Research on Human Milk and Lactation, held on September 15-19, 2000, in Tucson, Arizona. The presented sessions at the meeting are as diverse as the volume itself. These sessions include the impact of micronutrient deficiencies during lactation on maternal and infant health, the premature infant, developmental immunology, breastfeeding in the industrialized world, and viral transmission in milk. Whenever possible, the sessions were organized to include human population research, research showing the biological underpinnings of the effects on human health, and important methodological issues. This volume is a contemporary and influential tool for human milk biologists, breastfeeding epidemiologists, biochemists, immunologists, clinical specialists, and all professionals and researchers in the field.
Protecting Infants Through Human Milk
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Author : Larry K. Pickering
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Protecting Infants Through Human Milk written by Larry K. Pickering and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.
Short And Long Term Effects Of Breast Feeding On Child Health
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Author : Berthold Koletzko
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Short And Long Term Effects Of Breast Feeding On Child Health written by Berthold Koletzko and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
Proceedings of the 9th International Conference of the International Society for Research in Human Milk and Lactation (ISRHML), October 2-6, 1999, Bavaria, Germany. The quality of infant feeding is of major importance for child health development and well being, and breast feeding is the natural form of supplying food to the infant and is considered to be ideally adapted to the needs of both mother and child. This contributed volume therefore, brings together the research on the physiological foundations and on the biological effects of breast feeding, both short and long term. This book contains the work of scientists from over thirty countries, many of whom are leading researchers in their fields, and details papers presented by the invited speakers of the conference and short summaries of presentations of original research results.
The Immunology Of Infant Feeding
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Author : A. W. Wilkinson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-27
The Immunology Of Infant Feeding written by A. W. Wilkinson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-27 with Medical categories.
Though much thought is given to nutritional aspects of infant feeding, the complex immunological aspects have not been considered adequately, not only in the acceptance of the change to artificial feeding during this century, but also in developing feeds for total or supplementary feeding which will do minimal immunological damage. Besides food, mother's milk gives an orchestra of complex interacting bacteriostatic, bactericidal and anti-viral substances which contribute to the establishment of the normal intestinal flora. These mechanisms probably explain the many reports that breast fed babies get fewer infections than those fed artificially; deprivation from this effect of artificial feeding can be devastating in developing countries, with limited hygienic facilities, bad water supplies and sanitation. Infection is also more frequent in artificially fed infants in developed countries. Ingesting antigens is an important step in initiating the immune response, but the reSponse to such antigens is a controlled one, and besides antibody and cell mediated responses, partial tolerance, and immune exclusion (reduction of subsequent entry of antigen) occur. It is likely that food allergy, grossly neglected until recently, arises from disturbance of such mechanisms in the genetically vulnerable (immunodeficient) child.
Breast Feeding Early Influences On Later Health
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Author : Gail Ruth Goldberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-11-27
Breast Feeding Early Influences On Later Health written by Gail Ruth Goldberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-27 with Medical categories.
Breast-Feeding: Early Influences on Later Health is a new book which draws together areas of research in early lifel programming of adult health, with a unique focus on the post-natal period in terms of early life programming particularly the extent to which differences in infant feeding practices can lay an indelible imprint on metabolism and behaviour, and hence affect later function and risk of disease. This is an area where there is much less information currently available than there is for fetal programming, and the book raises many new questions and highlights numerous areas where further research is needed. The book chapters are arranged in three core sections: Chapters 1-4 lay down some of the basic biology of early life development; Chapters 5-9 examine how breast-milk and breast-feeding might ‘programme’ these processes by acting as modulators of development; Chapters 10-17 examine the epidemiological evidence that such effects do indeed exist. In addition the book includes unique chapters on the Evolution of human lactation and complementary feeding, The Macy-György Prize Lecture ‘My Milky Way’, updates on HIV and Breast-Feeding and on Early breastfeeding cessation and infant mortality in low-income countries, and measuring trace immune factors in human milk, all important topics that have such a critical impact on child health and survival in many countries.
