Immunoregulatory Mechanisms Of Interferon
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Immunoregulatory Mechanisms Of Interferon
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Author : Jorg Hermann Fritz
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-11
Immunoregulatory Mechanisms Of Interferon written by Jorg Hermann Fritz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-11 with categories.
Interferons (IFN) belong to the family of cytokines and have been described first in the late 1950s as an inhibitory factor of viral replication. Since then, the impact of interferon has been greatly expanded and its function comprises a role not only in different types of infection, cancer and autoimmunity but importantly also in immunehomeostasis. IFN have important anti-viral effects but it is becoming more and more evident that they are true immunomodulators and have an important impact on the development and maintenance of innate and adaptive immunity.
Interferons
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Author : Joe H. Thomas
language : en
Publisher: Nova Science Publishers
Release Date : 2012
Interferons written by Joe H. Thomas and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Interferon categories.
Interferons are cytokines that are very important in regulating both innate and adaptive immune response. Of the two different types of interferons, Type I interferons are potent mediators of the innate immune response against viruses and cancer. Type II interferons, mainly IFN-y enhances T cell polarisation in the lymph nodes that result in their expansion. This book discusses the characterisation, mechanisms of action and clinical applications of interferons. Topics include interferon-gamma, oligodendrocyte injury and inflammatory demyelination; the role of IFN-y in oesophageal squamous cell carcinoma; interferons in multiple sclerosis; the effect of interferons on NK cell activity in HIV infection and tumour cell development; and understanding the mechanisms of interaction between serine proteases, serine protease receptors and interferons.
Humoral Factors In Host Defense
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Author : Takeda Kagaku Shinkō Zaidan
language : en
Publisher:
Release Date : 1983
Humoral Factors In Host Defense written by Takeda Kagaku Shinkō Zaidan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Antibody formation categories.
Humoral Factors in Host Defense contains the proceedings of the First Takeda Science Foundation Symposium on Bioscience, held on October 28-30, 1982, in Kyoto, Japan. The symposium focused on the humoral factors regulating immune responses, with emphasis on T cell-derived immunoregulatory molecules; molecular mechanisms of interferons; factors involved in differentiation and activation of immunocytes; and the use of the molecular genetics approach to host defense factors. Organized into four parts encompassing 22 chapters, this volume begins with an overview of interleukin-2 and T cell-replac ...
Viral Gastroenteritis
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Author : Shunzo Chiba
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Viral Gastroenteritis written by Shunzo Chiba and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Recently, rapid developments have occurred in the field of viral gastroenteritis. This book is an update of fundamental and practical aspects of viral gastroenteritis. Among the various agents that cause viral gastroenteritis, group A rotaviruses and caliciviruses are the focus of this volume because of their clinical impact and the significance of new findings about them.
Interferon The 50th Anniversary
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Author : Paula M. Pitha
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-29
Interferon The 50th Anniversary written by Paula M. Pitha and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-29 with Medical categories.
A vital text for researchers and clinicians in the fields of virology and oncology alike, this book is a comprehensive guide to one of medicine’s most important tools that covers the most recent research. Important insights have been made in recent months that are challenging the accepted concept of the critical role of dsRNA in IFN induction. Recent work with genetically modified mice seems to confirm the original idea that interferon is the first cellular defense against viral infection.
Immunoregulation
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Author : Nicola Fabris
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunoregulation written by Nicola Fabris and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse quences. In order to assure aperfect balance within the enormous com plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres sor and helper T cells, lymphokine signals and genetic require ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely,in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro endocrine homeostasis.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Indoor Allergens
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1993-02-01
Indoor Allergens written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-02-01 with Science categories.
More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other allergic diseases. Many of these conditions are caused by exposure to allergens in indoor environments such as the house, work, and schoolâ€"where we spend as much as 98 percent of our time. Developed by medical, public health, and engineering professionals working together, this unique volume summarizes what is known about indoor allergens, how they affect human health, the magnitude of their effect on various populations, and how they can be controlled. The book addresses controversies, recommends research directions, and suggests how to assist and educate allergy patients, as well as professionals. Indoor Allergens presents a wealth of information about common indoor allergens and their varying effects, from significant hay fever to life-threatening asthma. The volume discusses sources of allergens, from fungi and dust mites to allergenic chemicals, plants, and animals, and examines practical measures for their control. Indoor Allergens discusses how the human airway and immune system respond to inhaled allergens and assesses patient testing methods, covering the importance of the patient's medical history and outlining procedures and approaches to interpretation for skin tests, in vitro diagnostic tests, and tests of patients' pulmonary function. This comprehensive and practical volume will be important to allergists and other health care providers; public health professionals; specialists in building design, construction, and maintenance; faculty and students in public health; and interested allergy patients.
Innate Immunity In Health And Disease
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Author : Shailendra K. Saxena
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-08-25
Innate Immunity In Health And Disease written by Shailendra K. Saxena and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Medical categories.
The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
Stress Response In Pathogenic Bacteria
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Author : Stephen P. Kidd
language : en
Publisher: CABI
Release Date : 2011
Stress Response In Pathogenic Bacteria written by Stephen P. Kidd and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
The ability of pathogenic bacteria to adapt to various chemical, biochemical and physical conditions within the human host and their ability to respond to stresses generated in these environments is a central feature of infectious diseases and the outcome of bacterial infection. This book covers the key aspects of this rapidly developing field, including the generation of stresses by the host immune system, bacterial response to reactive chemicals, and adaptation to environmental conditions of anatomical niches such as the gut, mouth and urogenital tract. It also addresses the increasing importance of different metal ions in the pathogenesis and survival of specific bacteria. With chapters by active research experts in the field, the book provides a comprehensive outline of the current understanding of this field, the latest developments and where future research is likely to be directed.