Immunotherapy Of Hepatocellular Carcinoma
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Immunotherapy In Hepatocellular Carcinoma
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Author : Weijia Fang
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-03
Immunotherapy In Hepatocellular Carcinoma written by Weijia Fang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-03 with Medical categories.
Immunotherapy Of Hepatocellular Carcinoma
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Author : Tim F. Greten
language : en
Publisher: Springer
Release Date : 2017-10-04
Immunotherapy Of Hepatocellular Carcinoma written by Tim F. Greten and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-04 with Medical categories.
In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.
Immunotherapy Of Hepatocellular Carcinoma
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Author : Tim F. Greten
language : en
Publisher: Springer
Release Date : 2018-08-22
Immunotherapy Of Hepatocellular Carcinoma written by Tim F. Greten and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-22 with Medical categories.
In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.
Mechanisms And Therapy Of Liver Cancer
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-02-10
Mechanisms And Therapy Of Liver Cancer written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-10 with Medical categories.
Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver Cancer, Immunotherapy of Liver Cancer, and Desmoplastic Tumor Microenvironment and Intrahepatic Cholangiocarcinoma Progression: Mechanisms and Therapeutic Implications. Provides the latest information on liver cancer research Offers outstanding and original reviews on a range of topics focused on liver cancer Serves as an indispensable reference on liver cancer for researchers and students alike
Biomarkers And Immunotherapy Of Hepatic Biliary Pancreatic Cancers
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Author : Yunfei Xu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-29
Biomarkers And Immunotherapy Of Hepatic Biliary Pancreatic Cancers written by Yunfei Xu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-29 with Medical categories.
Hepatic-biliary-pancreatic cancers, mainly including hepatocellular carcinoma, cholangiocarcinoma, gallbladder cancer, are highly aggressive malignancies with few treatment options and poor prognoses. Effects of the traditional systemic treatments such as chemotherapy and radiotherapy, are quite limited to hepatic-biliary-pancreatic cancers. For the patients who suffer from hepatic-biliary-pancreatic cancer and lose the opportunity of radical surgery, few targeted drugs are available. Even for the drugs in clinical trial, potential drug targets and prognostic biomarkers for hepatic-biliary-pancreatic cancer are less studied compared to other common cancers such as lung cancer. Prognostic biomarker study is the initiation to explore new drug targets and revelation of the underlying mechanisms of tumor progression.
Immunotherapy Combination Strategies In Unresectable Hepatocellular Carcinoma
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Author : Lorenza Rimassa
language : en
Publisher:
Release Date : 2022
Immunotherapy Combination Strategies In Unresectable Hepatocellular Carcinoma written by Lorenza Rimassa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Medical categories.
Immunotherapy In Hepatocellular Cancer Patients With Mild To Severe Liver Dysfunction Adjunctive Role Of The Albi Grade
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Author : David James Pinato
language : en
Publisher:
Release Date : 2020
Immunotherapy In Hepatocellular Cancer Patients With Mild To Severe Liver Dysfunction Adjunctive Role Of The Albi Grade written by David James Pinato and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Molecular Underpinnings Of Immunotherapy In The Treatment Of Hepatocellular Carcinoma And Surgical Implications
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Author : Philipp Haber
language : en
Publisher:
Release Date : 2024
Molecular Underpinnings Of Immunotherapy In The Treatment Of Hepatocellular Carcinoma And Surgical Implications written by Philipp Haber and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with categories.
Hepatocellular Carcinoma Moving Into The 21st Century An Issue Of Clinics In Liver Disease E Book
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Author : Catherine Frenette
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-10-22
Hepatocellular Carcinoma Moving Into The 21st Century An Issue Of Clinics In Liver Disease E Book written by Catherine Frenette and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-22 with Medical categories.
In collaboration with Consulting Editor, Dr. Norman Gitlin, Guest Editor Dr. Catherine Frenette has assembled expert authors to provide current updates on Hepatocellular Carcinoma (HCC). This issue asks important questions and provides answers and current thoughts on the staging and treatment of HCC. Clinical review articles are specifically dedicated to the following topics: The Changing Global Epidemiology of Hepatocellular Carcinoma; Prevention Strategies for HCC; Biomarkers or Biopsy for Diagnosis of HCC; Screening and Surveillance Strategies to Improve the Chance of Success; Imaging Diagnosis of HCC; Surgical Resection: Old dog--Any new tricks; Hepatocellular Carcinoma and Liver Transplant: How Will Organ Allocation Changes Affect the HCC Patient Within Transplant Criteria; Downstaging to Liver Transplant: Success Involves Choosing the Right Patient; Locoregional Therapies for Hepatocellular Carcinoma: What has Changed in the Past Ten Years; External Beam Radiotherapy: Is There a Place for This in HCC Treatment; Tyrosine Kinase Inhibitors and Hepatocellular Carcinoma; Immuno-oncology for Hepatocellular Carcinoma: The Present and the Future; Management of Side Effects of Systemic Therapies for HCC: Guide for the Hepatologist; and Why a Multi-disciplinary Tumor Board is Critical for Success with Hepatocellular Carcinoma. Readers will come away with the information they need to improve patient outcomes in the patient with HCC.
Cancer Immunotherapy Principles And Practice Second Edition
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Author : Lisa H. Butterfield, PhD
language : en
Publisher: Springer Publishing Company
Release Date : 2021-08-25
Cancer Immunotherapy Principles And Practice Second Edition written by Lisa H. Butterfield, PhD and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Medical categories.
Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field. Key Features: Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field Covers the basic principles and science behind cancer immunotherapy and tumor immunology Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs