Immunotoxicology And Immunopharmacology


Immunotoxicology And Immunopharmacology
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Immunotoxicology And Immunopharmacology


Immunotoxicology And Immunopharmacology
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Author : H Dean Jack
language : en
Publisher: CRC Press
Release Date : 1994-06-30

Immunotoxicology And Immunopharmacology written by H Dean Jack and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-06-30 with Medical categories.


The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.



Immunotoxicology And Immunopharmacology Third Edition


Immunotoxicology And Immunopharmacology Third Edition
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Author : Robert V. House
language : en
Publisher: CRC Press
Release Date : 2006-12-26

Immunotoxicology And Immunopharmacology Third Edition written by Robert V. House and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-26 with Medical categories.


Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history, an entire section covers the phylogeny and ontogeny of the immune system, spanning levels of biological complexity from earthworms to marine mammals.



Principles Of Immunopharmacology


Principles Of Immunopharmacology
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Author : Frans P. Nijkamp
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-01

Principles Of Immunopharmacology written by Frans P. Nijkamp and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-01 with Medical categories.


This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The first section of the book, covering a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts. The second section on immunodiagnostics has been further expanded to describe widely used molecular techniques and is followed by a systematic coverage of drugs affecting the immune system, revised to cover recent developments. The book concludes with a chapter on immunotoxicology. This third edition continues the unique format dealing with four related topics in a single volume, obviating the need to refer to several different textbooks. New aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first edition.



Molecular Immunotoxicology


Molecular Immunotoxicology
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Author : Emanuela Corsini
language : en
Publisher: John Wiley & Sons
Release Date : 2014-11-24

Molecular Immunotoxicology written by Emanuela Corsini and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-24 with Science categories.


The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.



Principles And Methods Of Immunotoxicology


Principles And Methods Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Elsevier
Release Date : 2004-10-14

Principles And Methods Of Immunotoxicology written by Jacques Descotes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-14 with Medical categories.


This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.



Immunotoxicology


Immunotoxicology
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Author : The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety
language : en
Publisher: Springer Science & Business Media
Release Date : 1987-02-28

Immunotoxicology written by The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-02-28 with Medical categories.


IX The International Seminar on the Immunological System as a Target for Toxic Damage was held at The Commission of the European Communities (CEC) in Luxembourg on 6-9 November 1984. It was organized by the CEC and the International Programme on Chemical Safety of UNEP/ILO/WHO with the support of the u. S. Environmental Protection Agency and the National Institute of Environmental Health Sciences - USA and with the participation of the International Society of Immunophar macology. These bodies are actively concerned with the scientific and applied aspects of immunotoxicology. The Seminar consisted of thirty-four invited papers and three major panel discussions covering current and future test strategies for the screening of immunotoxic substances, hypersensitivity and the health implications of immunotoxico logical problems. It was attended by more than 200 scien tists from 27 countries representing all the Member states of the European Economic Community and the six Regions of the World Health Organization. These scientists represented many different disciplines and interests. The Seminar's principal objectives were: a review of recent advances in knowledge concerning the structure, function and dysfunction of the immunological system; - a review of the effects of xenobiotics on the immune system in animals and humans; an examination of the human health implications of immunotoxicity; discussion and critical analysis of the procedures for the assessment of immunological damage, a discussion of needs for the further development of laboratory and epidemiological methods and their validation, and a consideration of current test strategies.



Identifying And Controlling Immunotoxic Substances


Identifying And Controlling Immunotoxic Substances
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Author :
language : en
Publisher: Office of Technology Assessment
Release Date : 1991

Identifying And Controlling Immunotoxic Substances written by and has been published by Office of Technology Assessment this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Antibody-toxin conjugates categories.




Immunotoxicity Of Metals And Immunotoxicology


Immunotoxicity Of Metals And Immunotoxicology
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Author : Anthony Dayan
language : en
Publisher: Springer
Release Date : 2012-12-02

Immunotoxicity Of Metals And Immunotoxicology written by Anthony Dayan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.


Considerable scientific and political interest has been expressed, parallelling public concern about the effects of chemicals on the immune system and the implications of those effects for health. Coupled with speculation about the magnitude and extent of the problem is discussion of needs for predictive testing and regulatory control measures. The first international seminar on the immunological system as a target for toxic damage was held in Luxembourg in 1984. It was organized by the International Programme on Chemical Safety (United Nations Environment Programme-International Labour Office World Health Organization) and the Commission of the European Communities with the support of the US Environmental Protection Agency and the National Institute of Environmental Health Sciences (USA) and the participation of the International Society of Immunopharmacology. In view of the perceived importance of imrnunotoxicity, it was considered necessary to organize a follow-up meeting. Thus, an international workshop on the immunotoxicity of metals and immuno toxicology was held in Hanover, Federal Republic of Germany, on 6-10 November 1989.



History Of Immunotoxicology


History Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Academic Press
Release Date : 2019-04-15

History Of Immunotoxicology written by Jacques Descotes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Medical categories.


History of Immunotoxicology offers the first book-length exploration of the development and importance of the field of immunotoxicology, describing the adverse health effects involving the immune system, hypersensitivity and autoimmunity. It explores new avenues of research and immunotoxicity evaluation, regulatory aspects of immunotoxicology, and the withdrawal/banning from the market of several approved drugs and chemicals due to their immunotoxic effects. In addition, clinical manifestations of immunotoxicity, such as anaphylaxis, opportunistic infections, lymphomas, cytokine storm, and immunotherapy are addressed. Finally, the book considers how the recent past can provide insights on the future practice of immunotoxicology. As preventive measures are implemented to reduce risks, including banning of chemicals or applications of one given chemical, current toxicologists may not be aware of the toxicity potential of chemicals. This book will be of interest to students and researchers in government, industry and academia who have an interest in immunotoxicology. Examines the development of immunotoxicology Provides context to current debates on the actual toxicity potential of chemicals Covers major developments and areas of immunotoxicology



Immunotoxicology Of Drugs And Chemicals Principles And Methods Of Immunotoxicology


Immunotoxicology Of Drugs And Chemicals Principles And Methods Of Immunotoxicology
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Author : Jacques Descotes
language : en
Publisher: Elsevier Science Serials
Release Date : 2004

Immunotoxicology Of Drugs And Chemicals Principles And Methods Of Immunotoxicology written by Jacques Descotes and has been published by Elsevier Science Serials this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.


This third thoroughly revised edition, written by a renowned expert in this rapidly expanding field, is a welcome and timely publication in the field of experimental and clinical immunotoxicology. Immunotoxicology is a young, but rapidly expanding area of toxicology. Since the second edition of this book was published in 1988, an increasing amount of data has resulted in the publication of many articles and reviews. This book covers the many general facets of current immunotoxicology - clinical, experimental, mechanistic and regulatory aspects, including a chapter on the immune system giving toxicologists unfamiliar with immunology the opportunity to acquire the minimal knowledge necessary to conduct and interpret immunotoxicity studies. A comprehensive chapter on adverse effects in relation to immunotoxicity is included in order to predict and understand the toxic effects of drugs and other chemicals in living beings. An effort is made to answer one of the perhaps most confusing issues confronting the student of immunotoxicology namely the identification of what constitutes an immunotoxic response and what does not. Researchers from different disciplines have shown interest in this new field, and presented results of their work on immunotoxicological issues from extremely varied perspectives. As a bridging discipline between immunology and toxicology, immunotoxicology is genuinely multidisciplinary, reflected in this excellent book.