Impact Of Gut Microbiota On Neurogenesis And Neurological Diseases During Early Life
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Impact Of Gut Microbiota On Neurogenesis And Neurological Diseases During Early Life
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Author : Tomás Cerdó
language : en
Publisher: Frontiers Media SA
Release Date : 2025-01-30
Impact Of Gut Microbiota On Neurogenesis And Neurological Diseases During Early Life written by Tomás Cerdó and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-30 with Medical categories.
In the last years, advances in omic technologies, such as 16S rDNA gene sequencing, metabolomics, and proteomics, have recently shown the association of the early gut microbiota not only with gastrointestinal disorders, but also with diseases affecting other distal organs, like the central nervous system (CNS), suggesting the existence of the “gut microbiota-brain axis” as a complex pathways system capable to regulate mood, behaviour and neurocognitive development. Despite the recognized importance of proper gut microbiota assembly for child's future health, these connections between the early-life gut microbiota and neurocognitive development in humans have not been thoroughly explored so far. Furthermore, most of this knowledge has been obtained from studies in animal models, including GF, antibiotic-treated, genetically modified, or humanised mice, and behavioural models, suggesting that the gut microbiota may serve as a biomarker to be explored and a target for mental diseases prevention and treatment. Complex communication between gut microbiota and brain is established during prenatal and early postnatal stages, in which profound changes in microbial colonization and cognitive development coincides in time but asynchronously regarding attaining peak and maturity. Although brain development begins in utero and continues during into adolescence, critical steps for establishment of cognitive, emotional and behaviour abilities occurs during early postnatal life, including neurulation, neurogenesis, neural migration, gliogenesis, synaptogenesis, myelination and synapse pruning.
Microbial Endocrinology The Microbiota Gut Brain Axis In Health And Disease
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Author : Mark Lyte
language : en
Publisher: Springer
Release Date : 2014-07-05
Microbial Endocrinology The Microbiota Gut Brain Axis In Health And Disease written by Mark Lyte and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-05 with Science categories.
The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.
The Gut Brain Axis
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Author : Niall Hyland
language : en
Publisher: Academic Press
Release Date : 2016-05-13
The Gut Brain Axis written by Niall Hyland and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-13 with Medical categories.
The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. - Focuses on specific areas in which the microbiota has been implicated in gut-brain communication - Examines common mechanisms and pathways by which the microbiota may influence brain and behavior - Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior
Neurobiology Of Depression
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Author : Francisco Lopez-Munoz
language : en
Publisher: CRC Press
Release Date : 2011-09-09
Neurobiology Of Depression written by Francisco Lopez-Munoz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-09 with Medical categories.
Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, mol
Enteric Glia
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Author : Brian D. Gulbransen
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01
Enteric Glia written by Brian D. Gulbransen and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.
The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography
The Enteric Nervous System
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Author : John Barton Furness
language : en
Publisher:
Release Date : 1987
The Enteric Nervous System written by John Barton Furness and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
Gerontology
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Author : Grazia D’Onofrio
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-07-04
Gerontology written by Grazia D’Onofrio and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-04 with Psychology categories.
Aging well and actively is the real objective of human being. This book is an up-to-date and realistic view on physiopathological mechanisms of aging and age-related diseases. The book includes topical contributions from multiple disciplines to support the fundamental goals of extending active life and enhancing its quality.
Brain Gut Interactions
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Author : Yvette Tache
language : en
Publisher: CRC Press
Release Date : 1991-02-22
Brain Gut Interactions written by Yvette Tache and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-02-22 with Science categories.
Brain-Gut Interactions serves as a reference source and stimulus for expanded research efforts aimed at unravelling the pathophysiology of brain-gut interactions. Within the general framework of brain-gut interactions, it covers the various areas in which this growing interdisciplinary field has evolved. Topics discussed in this volume include the topography and morphology of afferent and efferent connections between the gut and the medulla and hypothalamic nuclei, the role of afferent and efferent pathways in the regulation of gastrointestinal function, the brain's regulation of gastrointestinal secretory and motor function, and the function of peripheral and central cholecystokinin in the mechanisms of satiety. The final section of this book focuses on topics such as stress, emesis, visceral pain, and brain-related disorders of the intestine based on experimental and clinical data. Students and investigators working with brain-gut interactions, gastroenterologists, psychologists, and psychiatrists will find this book to be an essential reference resource.
Therapeutic Applications Of Honey And Its Phytochemicals
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Author : Muneeb U. Rehman
language : en
Publisher: Springer
Release Date : 2021-12-23
Therapeutic Applications Of Honey And Its Phytochemicals written by Muneeb U. Rehman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-23 with Medical categories.
Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals. It is reported to be beneficial in the treatment of various diseases, such as those affecting the respiratory, cardiovascular, gastrointestinal, and nervous systems, as well as diabetes mellitus and certain types of cancers; however, there is limited literature describing the use of honey in modern medicine. This book provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.
The Microbiome And The Brain
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Author : David Perlmutter
language : en
Publisher: CRC Press
Release Date : 2019-12-06
The Microbiome And The Brain written by David Perlmutter and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-06 with Medical categories.
Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.