In Situ Molecular Pathology And Co Expression Analyses

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In Situ Molecular Pathology And Co Expression Analyses

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Author : Gerard J. Nuovo
language : en
Publisher: Academic Press
Release Date : 2020-09-03

In Situ Molecular Pathology And Co Expression Analyses written by Gerard J. Nuovo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-03 with Science categories.

Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry. - Explains the theory and foundation of immunohistochemistry and in situ hybridization and presents easy-to-follow experimental protocols with tricks of the trade - Includes two new chapters: Recent improvements in immunohistochemistry and in situ hybridization, Quality control for immunohistochemistry and in situ hybridization: How to know if the color change is signal or background - The second edition also includes a detailed test to help one learn the basics of histologic interpretation of tissues and a separate detailed test in how to differentiate signal from background - Includes chapter-ending summaries of Key Points to Remember, bringing beginners up to speed with any seasoned veteran in the field - Thoughtfully tackles the molecular basis if IHC and ISH, along with application of that knowledge to improving the techniques is significant

Medical Image Processing For Improved Clinical Diagnosis

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Author : Swarnambiga, A.
language : en
Publisher: IGI Global
Release Date : 2018-08-31

Medical Image Processing For Improved Clinical Diagnosis written by Swarnambiga, A. and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-31 with Medical categories.

In the medical field, there is a constant need to improve professionals’ abilities to provide prompt and accurate diagnoses. The use of image and pattern recognizing software may provide support to medical professionals and enhance their abilities to properly identify medical issues. Medical Image Processing for Improved Clinical Diagnosis provides emerging research exploring the theoretical and practical aspects of computer-based imaging and applications within healthcare and medicine. Featuring coverage on a broad range of topics such as biomedical imaging, pattern recognition, and medical diagnosis, this book is ideally designed for medical practitioners, students, researchers, and others in the medical and engineering fields seeking current research on the use of images to enhance the accuracy of medical prognosis.

Molecular Surgical Pathology

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Author : Liang Cheng
language : en
Publisher: Springer Nature
Release Date : 2023-10-31

Molecular Surgical Pathology written by Liang Cheng and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-31 with Medical categories.

Since the first edition of this book in 2012, the field of molecular pathology has expanded exponentially. The advent of complete cancer genome sequencing, new diagnostic molecular tests, and biomarkers for targeted therapy and immunotherapy have demonstrated the importance of molecular tools both in patient care and in the practice of pathology. Furthermore, the development of many new molecular technologies has revolutionized the practice of modern pathology. The rapid growth of this field has led to an expansion of knowledge of molecular processes and many more clinical applications in our daily practice of surgical pathology. Thus, this updated second edition of Molecular Surgical Pathology aims to serve as the best available “quick reference” for pathologists, oncologists, geneticists, primary care physicians, and other medical professionals with an interest in this specialty. Molecular Surgical Pathology 2nd Edition focuses on the practical utility of molecular techniques and on molecular biomarkers for the practicing surgical pathologist. The emphasis is on the impact of molecular pathology for tumor classification, diagnosis and differential diagnosis, as well as its implications for patient management and personalized care. This concise overview of molecular surgical pathology and molecular classification of tumors of different organ sites will help not only practicing physicians, but also those in training, including residents and fellows in various disciplines.

Breast Pathology E Book

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Author : David J Dabbs
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-05-19

Breast Pathology E Book written by David J Dabbs and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-19 with Medical categories.

Written with useful practicality in mind, Breast Pathology, 3rd Edition, provides surgical pathologists with authoritative guidance on the selection and best use of proper diagnostic techniques when reporting on breast specimens. Dr. David J. Dabbs and a team of internationally acclaimed pathologists incorporate genomic and molecular information, gross and microscopic findings, radiologic and laboratory diagnosis, theranostics, and immunohistochemistry to cover every aspect of benign and malignant lesions of the breast, helping you minimize diagnostic variation and error in the sign-out room. - Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer. - Incorporates the latest classifications of breast pathology and molecular diagnosis. - Organizes each topical chapter around relevant genomic and molecular information, clinical presentation, gross and microscopic pathologic findings and diagnostic and molecular immunohistochemistry. - Maps immunohistochemistry for each entity according to diagnostic, theranostic, and genomic applications, with specific regard to disease entities in each chapter. - Discusses breast specimen handling in detail to assure proper sampling and processing for optimal molecular and immunohistochemistry resulting. - Supplies a convenient quick reference at the beginning of each chapter that includes all relevant diagnostic, theranostic, and genomic data for fast retrieval. - Features approximately 2,000 full-color pathological images that clearly depict clinical, radiological, molecular, immunohistochemical, and theranostic aspects of disease. - Includes biomarker guideline updates throughout. - Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays.

Targeting Protein Kinases For Cancer Therapy

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Author : David J. Matthews
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20

Targeting Protein Kinases For Cancer Therapy written by David J. Matthews and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Medical categories.

An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.

Molecular Diagnostics

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Author : George P. Patrinos
language : en
Publisher: Academic Press
Release Date : 2009-08-21

Molecular Diagnostics written by George P. Patrinos and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-21 with Science categories.

The 2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics and professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as academic institutions and hospital libraries. - Deals exclusively with the currently used molecular biology techniques to identify the underlying molecular defect of inherited diseases - Includes pharmacogenetics and pharmacogenomics relating to new cancer therapies - Provies a comprehensive guide through emerging concepts and demonstrates how the available mutation screening technology can be implemented in diagnostic laboratories and provide better healthcare

Index Medicus

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Author :
language : en
Publisher:
Release Date : 2004

Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medicine categories.

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Cumulated Index Medicus

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Author :
language : en
Publisher:
Release Date : 1994

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medicine categories.

Cancer Proteomics

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Author : Sayed S. Daoud
language : en
Publisher: Springer Science & Business Media
Release Date : 2008

Cancer Proteomics written by Sayed S. Daoud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.

This book covers current topics related to the use of proteomic strategies in cancer therapy as well as anticipated challenges that may arise from its application in daily practice. It details current technologies used in proteomics, examines the use proteomics in cell signaling, presents clinical applications of proteomics in cancer therapy, and looks at the role of the FDA in regulating the use of proteomics.

Macsween S Pathology Of The Liver E Book

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Author : Alastair D. Burt
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-05-22

Macsween S Pathology Of The Liver E Book written by Alastair D. Burt and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-22 with Medical categories.

Since its first publication more than 35 years ago, MacSween’s Pathology of the Liver, by Drs. Alastair D. Burt, Linda D. Ferrell, and Stefan G. Hübscher, has established itself as the definitive reference on liver pathology. The 7th Edition continues the tradition of excellence with more than 1,000 high-quality illustrations, coverage of the new and emerging diagnostic applications and techniques that pathologists must be familiar with, an up-to-date review of drug-induced injury, and much more. A must-have for every surgical pathologist, MacSween’s remains the most authoritative and comprehensive book in its field. Provides comprehensive, state-of-the-art coverage of all malignant and benign hepatobiliary disorders from an international "who’s who" in the field. Helps you quickly recognize the wide variety of liver appearances that result from infections, tumors, and tumor-like lesions, as well as organ damage caused by drugs and toxins. Features 1,000+ full-color illustrations that provide a complete visual guide to each tumor or tumor-like lesion and assist in the recognition and diagnosis of any tissue sample you’re likely to encounter. Incorporates relevant data from ancillary techniques (immunohistochemistry, cytogenetics, and molecular genetics), giving you the tools required to master the latest breakthroughs in diagnostic technology. Includes an updated chapter on mechanisms of liver disease, including coverage of regression and remodeling of disease and new information on next generation sequencing; an up-to-date review of drug-induced injury, including the effects of herbal and alternative medicines. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.