In Vitro Toxicity Testing Of Environmental Agents
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In Vitro Toxicity Testing Of Environmental Agents
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Author : Alan R. Kolber
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08
In Vitro Toxicity Testing Of Environmental Agents written by Alan R. Kolber and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Science categories.
These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa tion and ideas on the current approaches (both scientific and po litical) for toxic assessment of environmental agents. The poten tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview of the various cellular, subcellular, organ, animal, and genetic systems which have been used to assess the health effects of environmental agents. The scientific principles behind short term assays and an evaluation of their applicability to health effects monitoring and analysis were investigated. Included among major topics were: (1) the biochemistry and pharmacology of selected environmental agents; (2) molecular mechanisms of car cinogenesis, mutagenesis, and transformation; (3) bacterial muta genesis and toxicity; (4) mammalian cell mutagenesis, toxicity, and transformation; (5) in vitro carcinogens and mutagens; (6) teratogenic and other developmental toxic effects; and (7) the development of short-term neuro-behavioral toxicity assays.
In Vitro Toxicity Testing Of Environmental Agents
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Author : Alan R. Kolber
language : en
Publisher: Springer
Release Date : 1983
In Vitro Toxicity Testing Of Environmental Agents written by Alan R. Kolber and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa tion and ideas on the current approaches (both scientific and po litical) for toxic assessment of environmental agents. The poten tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview of the various cellular, subcellular, organ, animal, and genetic systems which have been used to assess the health effects of environmental agents. The scientific principles behind short term assays and an evaluation of their applicability to health effects monitoring and analysis were investigated. Included among major topics were: (1) the biochemistry and pharmacology of selected environmental agents; (2) molecular mechanisms of car cinogenesis, mutagenesis, and transformation; (3) bacterial muta genesis and toxicity; (4) mammalian cell mutagenesis, toxicity, and transformation; (5) in vitro carcinogens and mutagens; (6) teratogenic and other developmental toxic effects; and (7) the development of short-term neuro-behavioral toxicity assays.
In Vitro Toxicity Testing Of Environmental Agents
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Author : Alan R. Kolber
language : en
Publisher: Springer
Release Date : 2011-11-05
In Vitro Toxicity Testing Of Environmental Agents written by Alan R. Kolber and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-05 with Science categories.
These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa tion and ideas on the current approaches (both scientific and po litical) for toxic assessment of environmental agents. The poten tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview of the various cellular, subcellular, organ, animal, and genetic systems which have been used to assess the health effects of environmental agents. The scientific principles behind short term assays and an evaluation of their applicability to health effects monitoring and analysis were investigated. Included among major topics were: (1) the biochemistry and pharmacology of selected environmental agents; (2) molecular mechanisms of car cinogenesis, mutagenesis, and transformation; (3) bacterial muta genesis and toxicity; (4) mammalian cell mutagenesis, toxicity, and transformation; (5) in vitro carcinogens and mutagens; (6) teratogenic and other developmental toxic effects; and (7) the development of short-term neuro-behavioral toxicity assays.
Toxicity Testing For Assessment Of Environmental Agents
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-05-07
Toxicity Testing For Assessment Of Environmental Agents written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-07 with Nature categories.
Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.
In Vitro Toxicity Testing Of Environmental Agents Current And Future Possibilities Part A Survey Of Test Systems Volume 5a
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Author : AR Kolber (Ed)
language : en
Publisher:
Release Date : 1983
In Vitro Toxicity Testing Of Environmental Agents Current And Future Possibilities Part A Survey Of Test Systems Volume 5a written by AR Kolber (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.
In Vitro Toxicology Second Edition
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Author : Shayne C. Gad
language : en
Publisher: CRC Press
Release Date : 2000-11-02
In Vitro Toxicology Second Edition written by Shayne C. Gad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-02 with Medical categories.
Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists a broad range of in vitro models for use in either identifying or understanding most forms of toxicity. The availability of in vitro models spans both the full range of endpoints (irritation, sensitization, lethality, mutagenicity, and devlopmental toxicity) and the full spectrum of target organ systems (skin, eye, heart, liver, kidney, nervous system, etc.). Chapters are devoted to each of these speciality areas from a perspective of presenting the principal models and their uses and limitations. Chapters that overview the principles involved in the general selection and use of models, and that address the issues of safety concerns and regulatory acceptance of these methods are also included.
In Vitro Toxicity Testing Of Environmental Agents Current Nd Future Possibilities Part B Development Of Risk Assessment Guidelines Volume 5
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Author : AR Kolber (Ed)
language : en
Publisher:
Release Date : 1983
In Vitro Toxicity Testing Of Environmental Agents Current Nd Future Possibilities Part B Development Of Risk Assessment Guidelines Volume 5 written by AR Kolber (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.
In Vitro Toxicity Testing Of Environmental Agents Current And Future Possibilities
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Author : Alan R. Kolber
language : en
Publisher: Springer
Release Date : 1983-01-01
In Vitro Toxicity Testing Of Environmental Agents Current And Future Possibilities written by Alan R. Kolber and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-01-01 with Science categories.
'MRI in Clinical Practice' provides an easily accessible source of reference material to supplement existing texts, distilling a wide breadth of theoretical and practical information into a pocket-sized manual. The book covers the basic Physics behind MRI, quality assurance, up-to-date safety guidelines and a useful gallery of image artefacts. Part of the book focuses on the specific areas of the body in which MRI is currently exploited, describing how MRI is performed in practice. As well as covering routine clinical techniques, the latest advanced methods (e.g. spectroscopy, fMRI, diffusion, high field MRI) are discussed and placed into the context of clinical application. Written from both a Physics and Radiological point-of-view, the book has a wide multidisciplinary appeal and is specifically targeted at MRI practitioners or trainees, as well as post-graduate students, physicists, radiographers and radiologists.
In Vitro Toxicity Testing Of Environmental Agents
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Author : Nato Advanced Research Institute on "In Vitro Toxicity ... (1979 : Monte Carlo, Monaco)
language : en
Publisher:
Release Date : 1983
In Vitro Toxicity Testing Of Environmental Agents written by Nato Advanced Research Institute on "In Vitro Toxicity ... (1979 : Monte Carlo, Monaco) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Environmental health categories.
In Vitro Toxicology
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Author : Alok Dhawan
language : en
Publisher: Academic Press
Release Date : 2017-11-13
In Vitro Toxicology written by Alok Dhawan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-13 with Science categories.
In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. - Discusses new techniques and protocols in a clear and concise manner - includes examinations of nanotoxicity, genotoxicity and carcinogenicity - Explains practical laboratory methods and the theories behind in vitro testing