In Vivo In Vitro
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In Vitro In Vivo Correlations
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Author : David B. Young
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08
In Vitro In Vivo Correlations written by David B. Young and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.
This book represents the invited presentations and some of the posters presented at the conference entitled "In Vitro-In Vivo Relationship (IVIVR) Workshop" held in Sep tember, 1996. The workshop was organized by the IVIVR Cooperative Working Group which has drawn together scientists from a number of organizations and institutions, both academic and industrial. In addition to Elan Corporation, which is a drug delivery com pany specializing in the development of ER (Extended Release) dosage forms, the IVIVR Cooperative Working Group consists of collaborators from the University of Maryland at Baltimore, University College Dublin, Trinity College Dublin, and the University of Not tingham in the UK. The principal collaborators are: Dr. Jackie Butler, Elan Corporation Prof. Owen Corrigan, Trinity College Dublin Dr. lain Cumming, Elan Corporation Dr. John Devane, Elan Corporation Dr. Adrian Dunne, University College Dublin Dr. Stuart Madden, Elan Corporation Dr. Colin Melia, University of Nottingham Mr. Tom O'Hara, Elan Corporation Dr. Deborah Piscitelli, University of Maryland at Baltimore Dr. Araz Raoof, Elan Corporation Mr. Paul Stark, Elan Corporation Dr. David Young, University of Maryland at Baltimore The purpose of the workshop was to discuss new concepts and methods in the devel opment of in vitro-in vivo relationships for ER products. The original idea went back ap proximately 15 months prior to the workshop itself. For some time, the principal collaborators had been working together on various aspects of dosage form development.
In Vitro And In Vivo Tools In Drug Delivery Research For Optimum Clinical Outcomes
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Author : Ambikanandan Misra
language : en
Publisher: CRC Press
Release Date : 2018-06-22
In Vitro And In Vivo Tools In Drug Delivery Research For Optimum Clinical Outcomes written by Ambikanandan Misra and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-22 with Medical categories.
This book covers the essentials of drug delivery research and provides a unique forum for scientific experimental methods that are exclusively focused by the in-vitro, ex-vivo, and in-vivo methodologies of drug delivery research and felicitates translational research. The book includes recent and novel approaches in evaluation methods of transdermal, nasal, ocular, oral and intraoral, gastro-retentive, colon-targeted, and brain-targeted drug delivery systems. Providing up to date and comprehensive information, this text is invaluable to students, teachers, scientists, and others employed in the field of drug delivery.
Cellular In Vitro Testing
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Author : John Haycock
language : en
Publisher: CRC Press
Release Date : 2014-08-27
Cellular In Vitro Testing written by John Haycock and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-27 with Medical categories.
Growing cells in 2D under static conditions has long been the gold standard of cell culture, despite this method not being representative of the complex in vivo environment. The use of animal models also has clear ethical and scientific limitations, and increasingly the 3Rs (replacement, refinement, reduction) in relation to animal models are being integrated into the modern-day scientific practice. Focusing on new 3D in vitro methods now available to researchers, this book brings together examples of leading-edge work being conducted internationally for improving in vitro cell culture methods, in particular the use of systems for enabling cell culture under laminar flow and the use of 3D scaffolds for providing cells with a structure which replicates the function of the extracellular matrix and encouraging interactions more akin to an in vivo environment.
Microbial Behaviour In Vivo And In Vitro
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Author :
language : en
Publisher:
Release Date : 1964
Microbial Behaviour In Vivo And In Vitro written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with categories.
Monoclonal Antibody Production
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1999-05-06
Monoclonal Antibody Production written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-06 with Medical categories.
The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.
Pharmaceutical Product Development
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Author : Chilukuri Dakshina Murthy
language : en
Publisher: CRC Press
Release Date : 2007-02-12
Pharmaceutical Product Development written by Chilukuri Dakshina Murthy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-12 with Medical categories.
During the last two decades, the pharmaceutical industry has been under pressure to reduce development costs and the time needed to bring drugs to market in order to maximize return on investment and bring treatments to patients sooner. To meet these ends, pharmaceutical scientists working in the differing areas of pharmacy, pharmaceutics, and phar
Avoiding Cancer One Day At A Time
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Author : Lynne Eldridge
language : en
Publisher: Avoiding Cancer Now
Release Date : 2006-12
Avoiding Cancer One Day At A Time written by Lynne Eldridge and has been published by Avoiding Cancer Now this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12 with Family & Relationships categories.
The mortality rate from cancer hasn't changed in 60 years despite the billions invested to find a cure. Avoiding Cancer One Day At A Time provides solid, practical advice for preventing cancer by avoiding carcinogens and implementing lifestyle/dietary practices that modify cancer causing factors. Combining their experience in family medicine and epidemiology with their passion for disease prevention, the authors provide the most up to date and effective advice for preventing cancer from developing in ourselves and our loved ones. Many ?how to? examples for preventing cancer by being environmentally aware, avoiding infections, living the proper lifestyle and getting the proper nutrition are provided. Chapter by chapter summaries and listings of the latest cancer prevention web sites are great references. Worksheets assist readers in implementing the advice in very tangible ways, and the recipe collection of cancer avoiding meals is a winner!
The Development Of B Cells In Vivo And In Vitro
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Author : Rebecca Alice Keenan
language : en
Publisher:
Release Date : 2007
The Development Of B Cells In Vivo And In Vitro written by Rebecca Alice Keenan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Pharmacokinetics
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Author : Leslie Z. Benet
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pharmacokinetics written by Leslie Z. Benet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Pharmaceutical Medicine
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Author : Adrian Kilcoyne
language : en
Publisher: OUP Oxford
Release Date : 2013-05-23
Pharmaceutical Medicine written by Adrian Kilcoyne and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-23 with Medical categories.
The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas of pharmaceutical medicine adjacent to your current role. For healthcare professionals already working in the field, this book offers a guiding hand in difficult situations as well as supplying rapid access to the latest recommendations and guidelines. Written by authors with experience in the industry and drug regulation, this comprehensive and authoritative guide provides a shoulder to lean on throughout your pharmaceutical career.