Indications For And Implementation Of Anticoagulant Therapy In Atrial Fibrillation
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Indications For And Implementation Of Anticoagulant Therapy In Atrial Fibrillation
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Author : Sics Editore
language : en
Publisher: SICS Editore
Release Date : 2014-10-01
Indications For And Implementation Of Anticoagulant Therapy In Atrial Fibrillation written by Sics Editore and has been published by SICS Editore this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-01 with Medical categories.
Anticoagulant therapy is the only form of treatment that unquestionably has been shown to improve the prognosis of patients with atrial fibrillation (AF).The most important aspect in clinical practice is to identify and treat patients who will benefit from long-term anticoagulant therapy. The choice between warfarin and the new class of anticoagulants (apixaban, dabigatran, rivaroxaban) should be made individually taking into account the benefits and risks of the drugs as well as the patient’s wishes.
Handbook Of Oral Anticoagulation
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Author : Gregory Lip
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-03
Handbook Of Oral Anticoagulation written by Gregory Lip and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-03 with Medical categories.
An overview of the new oral warfarin alternatives, an important new area in therapy for cardiovascular disease, provided by a leading expert. Presented in a concise format Authored by a well-known expert Provides a user-friendly overview of the most important clinical trials
Atrial Fibrillation
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Author :
language : en
Publisher:
Release Date : 2014
Atrial Fibrillation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Atrial fibrillation (AF) is a very common problem. In England alone, approximately 835,000 people have AF.321 Through its effects on rate and rhythm, it is a major cause of morbidity. Through increasing susceptibility to stroke, it is a major cause of both morbidity and mortality. Despite the fact that AF is a major population problem, it is not necessarily well managed. Anecdotally, people with AF often describe the inadequate explanations they have been given at the time of first diagnosis both concerning the nature of the problem and the treatment options which are open to them. This may partly reflect the fact that many doctors, particularly those working in primary care, do not feel confident in AF management. Anticoagulation is a case in point. The 2006 atrial fibrillation NICE Guideline laid down criteria for anticoagulation - yet amongst patients with known AF, only 55% of those fulfilling the 2006 criteria for anticoagulant therapy currently receive it. Research into the shortfall in anticoagulant uptake indicates that it cannot be adequately explained by either bleeding risk or co-morbidities. The attitude of healthcare professionals and the perceived risk of anticoagulation could also be major factors limiting uptake. The shortfall in the prescribing of anticoagulants to patients with AF was clearly seen in the Sentinel Stroke National Audit Programme of the Royal College of Physicians. Of 11,939 patients admitted with stroke to hospitals in England, Wales and Northern Ireland in the first 3 months of 2013, approximately one fifth were in AF on admission. Of these only 36% were receiving an anticoagulant. Yet 38% were on an antiplatelet drug as sole antithrombotic therapy and 26 % were on no antithrombotic treatment. The rate and rhythm management of AF is also often perceived to be difficult. In discussions informing the scope of this guideline, the classification of AF into paroxysmal, persistent and permanent was considered to be a barrier to implementation of rate and rhythm care. While this classification is a natural sub-division which does help to inform management, it is important that it should not obscure the common underlying principles of heart rate and rhythm care which apply to the generality of AF patients. This guideline seeks to address these issues. The question of how best to provide a patient with a focussed care package including patient information and treatment options is considered. Stroke prevention is considered in detail both in terms of treatment strategies, risk thresholds and risk scoring and options for treatment. Finally rate and rhythm management are considered, in as far as possible based on the totality of AF, rather than on individual sub-categories. In considering rate and rhythm management, it is emphasised that patient symptoms should be the driver to timely consideration of alternative escalating management options. No clinical guideline can ever be complete and the constraints of the guideline process have meant that we have needed to focus on a number of specific areas. The current guideline is a partial update of the 2006 guideline. The evidence relating to some sections of the 2006 guideline, most particularly AF diagnosis, has not been updated and the original recommendations have been incorporated unchanged. It is also the case that there has been very rapid progress in a number of areas relating to AF in recent years. This has been reflected in recent NICE technology appraisals on dronedarone, dabigatran, rivaroxaban and apixaban. The evidence and the recommendations relating to these drugs have not been reconsidered in the current guideline. The existing technology appraisal recommendations have been incorporated into the updated guideline. We have not sought to distinguish which aspects of care should take place in specific settings. We recognise that models of care vary greatly both locally and nationally and that in many places aspects of AF care which might hitherto have been regarded as most suited to secondary care are now being undertaken in primary care. It seems likely that this trend will continue. We have therefore tried to avoid imposing artificial boundaries. The target audience of the guideline is any healthcare professional working in any setting who is involved in caring for patients with AF.
Anticoagulation Therapy
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Author : Joe F. Lau
language : en
Publisher: Springer
Release Date : 2018-04-16
Anticoagulation Therapy written by Joe F. Lau and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-16 with Medical categories.
This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.
Cancer Associated Thrombosis
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Author : Alok A. Khorana
language : en
Publisher: CRC Press
Release Date : 2007-09-26
Cancer Associated Thrombosis written by Alok A. Khorana and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-26 with Medical categories.
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
Anticoagulant Drugs
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Author : Mojca Božič-Mijovski
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-08-29
Anticoagulant Drugs written by Mojca Božič-Mijovski and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-29 with Medical categories.
Anticoagulant drugs are among the most frequently prescribed drugs in everyday clinical practice. In the past decades, several new direct oral anticoagulants were developed that changed the anticoagulant therapy landscape considerably. This book provides an extensive overview of all the known anticoagulants that can be useful for studying different aspects of the haemostatic system or as a starting point for new drug development. It is also a valuable tool for clinicians providing a description of the mode of action and management of therapy for anticoagulant drugs used in everyday clinical practice in different clinical settings, including direct oral anticoagulants dabigatran, rivaroxaban, apixaban and edoxaban.
Inpatient Anticoagulation
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Author : Margaret C. Fang
language : en
Publisher: John Wiley & Sons
Release Date : 2011-10-07
Inpatient Anticoagulation written by Margaret C. Fang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-07 with Medical categories.
The first practical guide for hospitalists on the use of anticoagulants in hospitalized patients This edited volume provides a comprehensive overview of the vital topic of anticoagulation in the hospital setting. Designed specifically for use by hospital-based clinicians and associated hospital-based staff, this fully evidence-based book addresses the most commonly used anticoagulant agents, the latest advances in anticoagulation drugs, and primary indications for their use at therapeutic levels. This thorough, easy-to-use reference summarizes the most important guidelines and medical literature on anticoagulation. It features a careful review of the epidemiology and treatment of complications associated with anticoagulants. Unique topics include transition of care and practical strategies for developing and implementing quality improvement programs to enhance the administration and safety of anticoagulants. This concise resource also covers: Antiplatelet medications The treatment and prevention of venous thromboembolism in medical patients Venous thromboembolism prophylaxis in surgical patients Peri-operative management of oral anticoagulants and antiplatelet agents Prevention of cardioembolic stroke Antithrombotics for ischemic stroke Antithrombotic therapy for non-ST elevation acute coronary syndrome Hemorrhagic complications of anticoagulants in hospitalized patients Heparin-induced thrombocytopenia Hospitalists and other members of the patient care team will find that Inpatient Anticoagulation answers their questions with dependable and timely information.
Essentials Of Atrial Fibrillation
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Author : Yee Guan Yap
language : en
Publisher: Springer
Release Date : 2014-09-25
Essentials Of Atrial Fibrillation written by Yee Guan Yap and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-25 with Medical categories.
This handbook offers timely investigation of current pharmaceutical trends, clinical guidelines, novel treatments, and ongoing pipeline developments, including ground-breaking advances in the use of novel oral anticoagulants. Atrial fibrillation (AF) affects an estimated 1–2% of the population and is the most common cause of sustained cardiac arrhythmia. Critically, the number of patients developing AF is expected to double in the next five decades, leading to increased incidence of stroke, heart failure and other serious thromboembolic events.
Non Vitamin K Antagonist Oral Anticoagulants
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Author : Eduard Shantsila
language : en
Publisher: Springer
Release Date : 2015-12-21
Non Vitamin K Antagonist Oral Anticoagulants written by Eduard Shantsila and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-21 with Medical categories.
This book is an essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
Atrial Fibrillation And Percutaneous Coronary Intervention
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Author : Andrea Rubboli
language : en
Publisher: Springer
Release Date : 2016-11-30
Atrial Fibrillation And Percutaneous Coronary Intervention written by Andrea Rubboli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-30 with Medical categories.
This book considers paradigmatic clinical cases in order to cast light on key issues relating to elective or emergency stent implantation and the use of oral anticoagulation (OAC) in patients with atrial fibrillation. The topics addressed include the optimal periprocedural antithrombotic treatment (uninterrupted vs interrupted OAC, intraprocedural use of heparin and glycoprotein IIb/IIIa inhibitors, etc.), the most appropriate type of stent (bare metal vs drug eluting vs “bioactive”), the optimal regimen (e.g., triple therapy of OAC, aspirin, and clopidogrel vs the combination of OAC and a single antiplatelet agent), and the most suitable duration of the antithrombotic treatment prescribed at discharge (1 vs 6–12 months). The case-based management recommendations will be of wide practical value in the current health care context, where percutaneous coronary intervention is available even to patients with relevant co-morbidities, such as those warranting long-term OAC, and the indications for OAC are much broader than in the past. The book will appeal especially to clinical and interventional cardiologists, internal medicine specialists, hematologists, and family physicians and will also be of interest to cardiology and internal medicine residents and fellows.