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Industrial Pharmaceutical Chemistry


Industrial Pharmaceutical Chemistry
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Industrial Pharmaceutical Chemistry


Industrial Pharmaceutical Chemistry
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Author : Hebah Abdel-Wahab
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2023-11-06

Industrial Pharmaceutical Chemistry written by Hebah Abdel-Wahab and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-06 with Technology & Engineering categories.


This book discusses the effects of prolonged hypoventilation, or a pulmonary condition on hypoxia, and hypercapnia, its effect on the formation of some joint diseases, and the types of natural medicine used in the treatment of each joint disease. You will also find methods used to calculate thermodynamic parameters. You can also learn optimized structures for these chemical compounds. The book includes a listing of the thermodynamic table for literature values for standard enthalpy of formation, and C-H and O-H Bond dissociation energizes energies for some chemical compounds; simple multi-fluorinated organic alcohols.



Industrial Pharmaceutical Biotechnology


Industrial Pharmaceutical Biotechnology
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Author : Heinrich Klefenz
language : en
Publisher: Wiley-VCH
Release Date : 2002-04-22

Industrial Pharmaceutical Biotechnology written by Heinrich Klefenz and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-22 with Medical categories.


This volume focuses on pharmaceutical biotechnology as a key area of life sciences. The complete range of concepts, processes and technologies of biotechnology is applied in modern industrial pharmaceutical research, development and production. The results of genome sequencing and studies of biological-genetic function are combined with chemical, micro-electronic and microsystem technology to produce medical devices and diagnostic biochips. A multitude of biologically active molecules is expanded by additional novel structures created with newly arranged gene clusters and bio-catalytic chemical processes. New organisational structures in the co-operation of institutes, companies and networks enable faster knowledge and product development and immediate application of the results of research and process development. This book is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.



Polymorphism In The Pharmaceutical Industry


Polymorphism In The Pharmaceutical Industry
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Author : Rolf Hilfiker
language : en
Publisher: John Wiley & Sons
Release Date : 2019-01-04

Polymorphism In The Pharmaceutical Industry written by Rolf Hilfiker and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-04 with Science categories.


"Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development" highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues. As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided. Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.



The Chemistry Of Process Development In Fine Chemical And Pharmaceutical Industry


The Chemistry Of Process Development In Fine Chemical And Pharmaceutical Industry
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Author : Someswara Rao
language : en
Publisher: John Wiley & Sons
Release Date : 2007-04-02

The Chemistry Of Process Development In Fine Chemical And Pharmaceutical Industry written by Someswara Rao and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-02 with Technology & Engineering categories.


This book brings together the chemical strategies used in the optimisation of organic reactions and processes, and highlights the practical and technological options available. This book offers: an encyclopedic treatment of organic chemistry from an industrial, process research and development, and manufacturing point of view plenty of examples to illustrate the scope and limitation of the strategies a comprehensive index organised by topic, reaction type, and reagent an extensive literature survey. This is an essential and comprehensive guide for experienced practitioners of chemical process research and development, fresh recruits to chemical industry R&D divisions, and academics who are interested in interacting with the chemical industry, optimising their synthetic strategies, and enriching the field of atom economy.



Essentials Of Pharmaceutical Chemistry


Essentials Of Pharmaceutical Chemistry
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Author : Donald Cairns
language : en
Publisher: Pharmaceutical Press
Release Date : 2012

Essentials Of Pharmaceutical Chemistry written by Donald Cairns and has been published by Pharmaceutical Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems



Research And Development In The Chemical And Pharmaceutical Industry


Research And Development In The Chemical And Pharmaceutical Industry
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Author : Peter Bamfield
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13

Research And Development In The Chemical And Pharmaceutical Industry written by Peter Bamfield and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Science categories.


A guide for younger R&D chemists as to how they can quickly evolve skills built around three factors -- people, knowledge and time. It covers the management of scientific personnel, management within a variety of R & D organizational structures, creating a climate of innovation, the management of projects including the time management and communication aspects of the job. As such, it teaches the vital managerial aspects of scientific jobs in industry, which are not taught at university, providing a deep and detailed insight into the intricacies of managing research. The text is divided neatly into four sections: * Harnessing the Human Resource * Organising for an Innovative Environment * Creativity and Innovation * Project Management of Innovation The author, Peter Bamfield, is now working as a consultant. Due to his long experience in the chemical industry, he was elected President of the Royal Society of Chemistry's Industrial Affairs Division, and thus has a profound first-hand view of staff, companies and organizations in and around the industry. This third edition has been revised and updated to take into account global developments and recent changes in regulatory affairs.



Research And Development Management In The Chemical And Pharmaceutical Industry


Research And Development Management In The Chemical And Pharmaceutical Industry
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Author : Peter Bamfield
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06

Research And Development Management In The Chemical And Pharmaceutical Industry written by Peter Bamfield and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.


Mastering management skills is hard to achieve by newcomers starting their careers in the chemical industry. The message coming from there is that good chemists swiftly have to become good managers if they are to survive and progress in today's competitive climate. This book is designed to help guide younger R & D chemists to ways in which they can quickly evolve skills which are built around three factors - people, knowledge and time. It covers the management of scientific personnel, management within a variety of R & D organisational structures, creating a climate of innovation, the management of projects including the time management and communication aspects of the job. The author, Peter Bamfield, is now working as a consultant. Due to his long experience in the chemical industry, he was elected President of the Royal Society of Chemistry's Industrial Affairs Division. This second edition of the book has been revised and updated to take recent global developments and restructuring in the chemical industry into account, as well as the rising importance of information technology in management.



Process Chemistry In The Pharmaceutical Industry


Process Chemistry In The Pharmaceutical Industry
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Author : Kumar Gadamasetti
language : en
Publisher: CRC Press
Release Date : 1999-05-06

Process Chemistry In The Pharmaceutical Industry written by Kumar Gadamasetti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-06 with Medical categories.


Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers—offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various specialties in the development of new drugs. Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industry is sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists; and upper-level undergraduate and graduate students in these disciplines.



Practical Process Research And Development


Practical Process Research And Development
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Author : Neal G. Anderson
language : en
Publisher: Academic Press
Release Date : 2012-05-23

Practical Process Research And Development written by Neal G. Anderson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-23 with Science categories.


Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights:• Reflects the current thinking in chemical process R&D for small molecules• Retains similar structure and orientation to the first edition. • Contains approx. 85% new material• Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up)• Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes)• Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes



Solid State Characterization Of Pharmaceuticals


Solid State Characterization Of Pharmaceuticals
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Author : Richard A. Storey
language : en
Publisher: John Wiley & Sons
Release Date : 2011-03-31

Solid State Characterization Of Pharmaceuticals written by Richard A. Storey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-31 with Science categories.


The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. The following topics are included: Physical properties and processes Thermodynamics Intellectual guidance X-ray diffraction Spectroscopy Microscopy Particle sizing Mechanical properties Vapour sorption Thermal analysis & Calorimetry Polymorph prediction Form selection